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Page 1
Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation.
Minniti CP, Sable C, Campbell A, Rana S, Ensing G, Dham N, Onyekwere O, Nouraie M, Kato GJ, Gladwin MT, Castro OL, Gordeuk VR. Minniti CP, et al. Among authors: gordeuk vr. Haematologica. 2009 Mar;94(3):340-7. doi: 10.3324/haematol.13812. Epub 2009 Feb 11. Haematologica. 2009. PMID: 19211639 Free PMC article. Clinical Trial.
Echocardiographic findings in patients with sickle cell disease.
Naoman SG, Nouraie M, Castro OL, Nwokolo C, Fadojutimi-Akinsiku M, Diaz S, Willie-Carnegie G, Andrews N, Gordeuk VR. Naoman SG, et al. Among authors: gordeuk vr. Ann Hematol. 2010 Jan;89(1):61-6. doi: 10.1007/s00277-009-0764-0. Epub 2009 Jun 2. Ann Hematol. 2010. PMID: 19488751
Prospective evaluation of haemoglobin oxygen saturation at rest and after exercise in paediatric sickle cell disease patients.
Campbell A, Minniti CP, Nouraie M, Arteta M, Rana S, Onyekwere O, Sable C, Ensing G, Dham N, Luchtman-Jones L, Kato GJ, Gladwin MT, Castro OL, Gordeuk VR. Campbell A, et al. Among authors: gordeuk vr. Br J Haematol. 2009 Nov;147(3):352-9. doi: 10.1111/j.1365-2141.2009.07854.x. Epub 2009 Aug 19. Br J Haematol. 2009. PMID: 19694721 Free PMC article.
Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease.
Gordeuk VR, Campbell A, Rana S, Nouraie M, Niu X, Minniti CP, Sable C, Darbari D, Dham N, Onyekwere O, Ammosova T, Nekhai S, Kato GJ, Gladwin MT, Castro OL. Gordeuk VR, et al. Blood. 2009 Nov 19;114(21):4639-44. doi: 10.1182/blood-2009-04-218040. Epub 2009 Sep 1. Blood. 2009. PMID: 19724057 Free PMC article.
NT-proBNP as a marker of cardiopulmonary status in sickle cell anaemia in Africa.
Aliyu ZY, Suleiman A, Attah E, Mamman AI, Babadoko A, Nouraie M, Mendelsohn L, Kato GJ, Gordeuk VR, Gladwin MT. Aliyu ZY, et al. Among authors: gordeuk vr. Br J Haematol. 2010 Jul;150(1):102-7. doi: 10.1111/j.1365-2141.2010.08195.x. Epub 2010 Apr 16. Br J Haematol. 2010. PMID: 20408845 Free PMC article.
Pulmonary hypertension and NO in sickle cell.
Gladwin MT, Barst RJ, Castro OL, Gordeuk VR, Hillery CA, Kato GJ, Kim-Shapiro DB, Machado R, Morris CR, Steinberg MH, Vichinsky EP. Gladwin MT, et al. Among authors: gordeuk vr. Blood. 2010 Aug 5;116(5):852-4. doi: 10.1182/blood-2010-04-282095. Blood. 2010. PMID: 20688967 Free PMC article. No abstract available.
Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow up in children and adolescents with sickle cell anemia.
Gordeuk VR, Minniti CP, Nouraie M, Campbell AD, Rana SR, Luchtman-Jones L, Sable C, Dham N, Ensing G, Prchal JT, Kato GJ, Gladwin MT, Castro OL. Gordeuk VR, et al. Haematologica. 2011 Jan;96(1):33-40. doi: 10.3324/haematol.2010.030767. Epub 2010 Sep 30. Haematologica. 2011. PMID: 20884713 Free PMC article.
Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial.
Gladwin MT, Kato GJ, Weiner D, Onyekwere OC, Dampier C, Hsu L, Hagar RW, Howard T, Nuss R, Okam MM, Tremonti CK, Berman B, Villella A, Krishnamurti L, Lanzkron S, Castro O, Gordeuk VR, Coles WA, Peters-Lawrence M, Nichols J, Hall MK, Hildesheim M, Blackwelder WC, Baldassarre J, Casella JF; DeNOVO Investigators. Gladwin MT, et al. Among authors: gordeuk vr. JAMA. 2011 Mar 2;305(9):893-902. doi: 10.1001/jama.2011.235. JAMA. 2011. PMID: 21364138 Free PMC article. Clinical Trial.
Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity.
Machado RF, Barst RJ, Yovetich NA, Hassell KL, Kato GJ, Gordeuk VR, Gibbs JS, Little JA, Schraufnagel DE, Krishnamurti L, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Onyekwere O, Castro OL, Sachdev V, Waclawiw MA, Woolson R, Goldsmith JC, Gladwin MT; walk-PHaSST Investigators and Patients. Machado RF, et al. Among authors: gordeuk vr. Blood. 2011 Jul 28;118(4):855-64. doi: 10.1182/blood-2010-09-306167. Epub 2011 Apr 28. Blood. 2011. PMID: 21527519 Free PMC article. Clinical Trial.
Predictors of osteoclast activity in patients with sickle cell disease.
Nouraie M, Cheng K, Niu X, Moore-King E, Fadojutimi-Akinsi MF, Minniti CP, Sable C, Rana S, Dham N, Campbell A, Ensing G, Kato GJ, Gladwin MT, Castro OL, Gordeuk VR. Nouraie M, et al. Among authors: gordeuk vr. Haematologica. 2011 Aug;96(8):1092-8. doi: 10.3324/haematol.2011.042499. Epub 2011 May 5. Haematologica. 2011. PMID: 21546502 Free PMC article.
Laboratory and echocardiography markers in sickle cell patients with leg ulcers.
Minniti CP, Taylor JG 6th, Hildesheim M, O'Neal P, Wilson J, Castro O, Gordeuk VR, Kato GJ. Minniti CP, et al. Among authors: gordeuk vr. Am J Hematol. 2011 Aug;86(8):705-8. doi: 10.1002/ajh.22065. Epub 2011 May 31. Am J Hematol. 2011. PMID: 21630312 Free PMC article. Clinical Trial.
Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom.
Sachdev V, Kato GJ, Gibbs JS, Barst RJ, Machado RF, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli EM, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JG 6th, Hannoush H, Goldsmith JC, Gladwin MT, Gordeuk VR; Walk-PHASST Investigators. Sachdev V, et al. Among authors: gordeuk vr. Circulation. 2011 Sep 27;124(13):1452-60. doi: 10.1161/CIRCULATIONAHA.111.032920. Epub 2011 Sep 6. Circulation. 2011. PMID: 21900080 Free PMC article. Clinical Trial.
Pulmonary artery pressure and iron deficiency in patients with upregulation of hypoxia sensing due to homozygous VHL(R200W) mutation (Chuvash polycythemia).
Sable CA, Aliyu ZY, Dham N, Nouraie M, Sachdev V, Sidenko S, Miasnikova GY, Polyakova LA, Sergueeva AI, Okhotin DJ, Bushuev V, Remaley AT, Niu X, Castro OL, Gladwin MT, Kato GJ, Prchal JT, Gordeuk VR. Sable CA, et al. Among authors: gordeuk vr. Haematologica. 2012 Feb;97(2):193-200. doi: 10.3324/haematol.2011.051839. Epub 2011 Oct 11. Haematologica. 2012. PMID: 21993671 Free PMC article.
Clinical trial implementation and recruitment: lessons learned from the early closure of a randomized clinical trial.
Peters-Lawrence MH, Bell MC, Hsu LL, Osunkwo I, Seaman P, Blackwood M, Guillaume E, Bellevue R, Krishnamurti L, Smith WR, Dampier CD, Minniti CP; Sickle Cell Disease Clinical Research Network (SCDCRN). Peters-Lawrence MH, et al. Contemp Clin Trials. 2012 Mar;33(2):291-7. doi: 10.1016/j.cct.2011.11.018. Epub 2011 Dec 2. Contemp Clin Trials. 2012. PMID: 22155024 Free PMC article. Clinical Trial.
Inpatient management of sickle cell pain: a 'snapshot' of current practice.
Miller ST, Kim HY, Weiner D, Wager CG, Gallagher D, Styles L, Dampier CD; Investigators of the Sickle Cell Disease Clinical Research Network (SCDCRN). Miller ST, et al. Am J Hematol. 2012 Mar;87(3):333-6. doi: 10.1002/ajh.22265. Epub 2012 Jan 9. Am J Hematol. 2012. PMID: 22231150 Free PMC article.
Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates.
Novelli EM, Kato GJ, Ragni MV, Zhang Y, Hildesheim ME, Nouraie M, Barge S, Meyer MP, Hassett AC, Gordeuk VR, Gladwin MT, Isenberg JS. Novelli EM, et al. Among authors: gordeuk vr. Am J Hematol. 2012 Mar;87(3):326-30. doi: 10.1002/ajh.22274. Epub 2012 Feb 8. Am J Hematol. 2012. PMID: 22318901 Free PMC article.
A novel molecular signature for elevated tricuspid regurgitation velocity in sickle cell disease.
Desai AA, Zhou T, Ahmad H, Zhang W, Mu W, Trevino S, Wade MS, Raghavachari N, Kato GJ, Peters-Lawrence MH, Thiruvoipati T, Turner K, Artz N, Huang Y, Patel AR, Yuan JX, Gordeuk VR, Lang RM, Garcia JG, Machado RF. Desai AA, et al. Among authors: gordeuk vr. Am J Respir Crit Care Med. 2012 Aug 15;186(4):359-68. doi: 10.1164/rccm.201201-0057OC. Epub 2012 Jun 7. Am J Respir Crit Care Med. 2012. PMID: 22679008 Free PMC article.
Cobalamin status in sickle cell disease.
Ajayi OI, Bwayo-Weaver S, Chirla S, Serlemitsos-Day M, Daniel M, Nouraie M, Edwards K, Castro O, Lombardo F, Gordeuk VR. Ajayi OI, et al. Among authors: gordeuk vr. Int J Lab Hematol. 2013 Feb;35(1):31-7. doi: 10.1111/j.1751-553X.2012.01457.x. Epub 2012 Jul 26. Int J Lab Hematol. 2013. PMID: 22830455 Free PMC article.
The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe.
Nouraie M, Lee JS, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss TB, Zeng Q, Kato GJ, Gibbs JS, Hildesheim ME, Sachdev V, Barst RJ, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Goldsmith JC, Gordeuk VR, Gladwin MT; Walk-PHASST Investigators and Patients. Nouraie M, et al. Among authors: gordeuk vr. Haematologica. 2013 Mar;98(3):464-72. doi: 10.3324/haematol.2012.068965. Epub 2012 Sep 14. Haematologica. 2013. PMID: 22983573 Free PMC article.
Genetic determinants of haemolysis in sickle cell anaemia.
Milton JN, Rooks H, Drasar E, McCabe EL, Baldwin CT, Melista E, Gordeuk VR, Nouraie M, Kato GR, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Rana S, Castro O, Zhang Y, Thein SL, Sebastiani P, Gladwin MT; Walk-PHAAST Investigators; Steinberg MH. Milton JN, et al. Among authors: gordeuk vr. Br J Haematol. 2013 Apr;161(2):270-8. doi: 10.1111/bjh.12245. Epub 2013 Feb 14. Br J Haematol. 2013. PMID: 23406172 Free PMC article. Clinical Trial.
Clinical correlates of acute pulmonary events in children and adolescents with sickle cell disease.
Paul R, Minniti CP, Nouraie M, Luchtman-Jones L, Campbell A, Rana S, Onyekwere O, Darbari DS, Ajayi O, Arteta M, Ensing G, Sable C, Dham N, Kato GJ, Gladwin MT, Castro OL, Gordeuk VR. Paul R, et al. Among authors: gordeuk vr. Eur J Haematol. 2013 Jul;91(1):62-8. doi: 10.1111/ejh.12118. Epub 2013 May 3. Eur J Haematol. 2013. PMID: 23560516 Free PMC article.
Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia.
Arteta M, Campbell A, Nouraie M, Rana S, Onyekwere OC, Ensing G, Sable C, Dham N, Darbari D, Luchtman-Jones L, Kato GJ, Gladwin MT, Castro OL, Minniti CP, Gordeuk VR. Arteta M, et al. Among authors: gordeuk vr. J Pediatr Hematol Oncol. 2014 Apr;36(3):185-9. doi: 10.1097/MPH.0000000000000011. J Pediatr Hematol Oncol. 2014. PMID: 24309610 Free PMC article.
An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease.
Klings ES, Machado RF, Barst RJ, Morris CR, Mubarak KK, Gordeuk VR, Kato GJ, Ataga KI, Gibbs JS, Castro O, Rosenzweig EB, Sood N, Hsu L, Wilson KC, Telen MJ, Decastro LM, Krishnamurti L, Steinberg MH, Badesch DB, Gladwin MT; American Thoracic Society Ad Hoc Committee on Pulmonary Hypertension of Sickle Cell Disease. Klings ES, et al. Among authors: gordeuk vr. Am J Respir Crit Care Med. 2014 Mar 15;189(6):727-40. doi: 10.1164/rccm.201401-0065ST. Am J Respir Crit Care Med. 2014. PMID: 24628312 Free PMC article.
Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom.
Gladwin MT, Barst RJ, Gibbs JS, Hildesheim M, Sachdev V, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Berman Rosenzweig E, Badesch DB, Lanzkron S, Castro OL, Taylor JG 6th, Goldsmith JC, Kato GJ, Gordeuk VR, Machado RF; walk-PHaSST Investigators and Patients. Gladwin MT, et al. Among authors: gordeuk vr. PLoS One. 2014 Jul 2;9(7):e99489. doi: 10.1371/journal.pone.0099489. eCollection 2014. PLoS One. 2014. PMID: 24988120 Free PMC article. Clinical Trial.
Reply: Practice guideline for pulmonary hypertension in sickle cell: direct evidence needed before universal adoption.
Klings ES, Machado RF, Morris CR, Gordeuk VR, Kato GJ, Ataga KI, Castro O, Hsu L, Telen MJ, Krishnamurti L, Steinberg MH, Gladwin MT; ATS Clinical Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension in Sickle Cell Disease Committee. Klings ES, et al. Among authors: gordeuk vr. Am J Respir Crit Care Med. 2014 Jul 15;190(2):238-40. doi: 10.1164/rccm.201404-0733LE. Am J Respir Crit Care Med. 2014. PMID: 25025360 Free PMC article. No abstract available.
The genetics of hemoglobin A2 regulation in sickle cell anemia.
Griffin PJ, Sebastiani P, Edward H, Baldwin CT, Gladwin MT, Gordeuk VR, Chui DH, Steinberg MH. Griffin PJ, et al. Among authors: gordeuk vr. Am J Hematol. 2014 Nov;89(11):1019-23. doi: 10.1002/ajh.23811. Epub 2014 Aug 4. Am J Hematol. 2014. PMID: 25042611 Free PMC article.
Iron, inflammation, and early death in adults with sickle cell disease.
van Beers EJ, Yang Y, Raghavachari N, Tian X, Allen DT, Nichols JS, Mendelsohn L, Nekhai S, Gordeuk VR, Taylor JG 6th, Kato GJ. van Beers EJ, et al. Among authors: gordeuk vr. Circ Res. 2015 Jan 16;116(2):298-306. doi: 10.1161/CIRCRESAHA.116.304577. Epub 2014 Nov 6. Circ Res. 2015. PMID: 25378535 Free PMC article. Clinical Trial.
Complications in children and adolescents with Chuvash polycythemia.
Sergueeva AI, Miasnikova GY, Polyakova LA, Nouraie M, Prchal JT, Gordeuk VR. Sergueeva AI, et al. Among authors: gordeuk vr. Blood. 2015 Jan 8;125(2):414-5. doi: 10.1182/blood-2014-10-604660. Blood. 2015. PMID: 25573974 Free PMC article. No abstract available.
Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.
Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR. Zhang X, et al. Among authors: gordeuk vr. Hum Genet. 2015 Aug;134(8):895-904. doi: 10.1007/s00439-015-1572-3. Epub 2015 May 30. Hum Genet. 2015. PMID: 26025476 Free PMC article.
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Saraf SL, Zhang X, Shah B, Kanias T, Gudehithlu KP, Kittles R, Machado RF, Arruda JA, Gladwin MT, Singh AK, Gordeuk VR. Saraf SL, et al. Among authors: gordeuk vr. Haematologica. 2015 Oct;100(10):1275-84. doi: 10.3324/haematol.2015.124875. Epub 2015 Jul 23. Haematologica. 2015. PMID: 26206798 Free PMC article.
Prospective study of thrombosis and thrombospondin-1 expression in Chuvash polycythemia.
Sergueeva A, Miasnikova G, Shah BN, Song J, Lisina E, Okhotin DJ, Nouraie M, Nekhai S, Ammosova T, Niu XM, Prchal JT, Zhang X, Gordeuk VR. Sergueeva A, et al. Among authors: gordeuk vr. Haematologica. 2017 May;102(5):e166-e169. doi: 10.3324/haematol.2016.158170. Epub 2017 Jan 19. Haematologica. 2017. PMID: 28104701 Free PMC article. No abstract available.
A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease.
Zhang X, Shah BN, Zhang W, Saraf SL, Miasnikova G, Sergueeva A, Ammosova T, Niu X, Nouraie M, Nekhai S, Castro O, Gladwin MT, Prchal JT, Garcia JG, Machado RF, Gordeuk VR. Zhang X, et al. Among authors: gordeuk vr. Hum Mol Genet. 2016 Oct 15;25(20):4601-4609. doi: 10.1093/hmg/ddw299. Hum Mol Genet. 2016. PMID: 28173069 Free PMC article.
Association of circulating transcriptomic profiles with mortality in sickle cell disease.
Desai AA, Lei Z, Bahroos N, Maienschein-Cline M, Saraf SL, Zhang X, Shah BN, Nouraie SM, Abbasi T, Patel AR, Lang RM, Lussier Y, Garcia JGN, Gordeuk VR, Machado RF. Desai AA, et al. Among authors: gordeuk vr. Blood. 2017 Jun 1;129(22):3009-3016. doi: 10.1182/blood-2016-11-752279. Epub 2017 Apr 3. Blood. 2017. PMID: 28373264 Free PMC article.
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