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Page 1
Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO.
Wingender G, Garbi N, Schumak B, Jüngerkes F, Endl E, von Bubnoff D, Steitz J, Striegler J, Moldenhauer G, Tüting T, Heit A, Huster KM, Takikawa O, Akira S, Busch DH, Wagner H, Hämmerling GJ, Knolle PA, Limmer A. Wingender G, et al. Among authors: knolle pa. Eur J Immunol. 2006 Jan;36(1):12-20. doi: 10.1002/eji.200535602. Eur J Immunol. 2006. PMID: 16323249 Free article.
Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity.
Kern M, Popov A, Scholz K, Schumak B, Djandji D, Limmer A, Eggle D, Sacher T, Zawatzky R, Holtappels R, Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA. Kern M, et al. Among authors: knolle pa. Gastroenterology. 2010 Jan;138(1):336-46. doi: 10.1053/j.gastro.2009.08.057. Epub 2009 Sep 6. Gastroenterology. 2010. PMID: 19737567
Bioluminescence imaging allows measuring CD8 T cell function in the liver.
Stabenow D, Frings M, Trück C, Gärtner K, Förster I, Kurts C, Tüting T, Odenthal M, Dienes HP, Cederbrant K, Protzer U, Knolle PA. Stabenow D, et al. Among authors: knolle pa. Hepatology. 2010 Apr;51(4):1430-7. doi: 10.1002/hep.23575. Hepatology. 2010. PMID: 20373369
Cross-priming in health and disease.
Kurts C, Robinson BW, Knolle PA. Kurts C, et al. Among authors: knolle pa. Nat Rev Immunol. 2010 Jun;10(6):403-14. doi: 10.1038/nri2780. Nat Rev Immunol. 2010. PMID: 20498667 Review.
Taking off the brakes: T cell immunity in the liver.
Kern M, Popov A, Kurts C, Schultze JL, Knolle PA. Kern M, et al. Among authors: knolle pa. Trends Immunol. 2010 Aug;31(8):311-7. doi: 10.1016/j.it.2010.06.001. Epub 2010 Jul 9. Trends Immunol. 2010. PMID: 20619740 Review.
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.
Beyer M, Thabet Y, Müller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld EA, Böttcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL. Beyer M, et al. Among authors: knolle pa. Nat Immunol. 2011 Aug 14;12(9):898-907. doi: 10.1038/ni.2084. Nat Immunol. 2011. PMID: 21841785 Free PMC article.
Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis.
Schwandt T, Schumak B, Gielen GH, Jüngerkes F, Schmidbauer P, Klocke K, Staratschek-Jox A, van Rooijen N, Kraal G, Ludwig-Portugall I, Franken L, Wehner S, Kalff JC, Weber O, Kirschning C, Coch C, Kalinke U, Wenzel J, Kurts C, Zawatzky R, Holzmann B, Layland L, Schultze JL, Burgdorf S, den Haan JM, Knolle PA, Limmer A. Schwandt T, et al. Among authors: knolle pa. EMBO J. 2012 Jan 4;31(1):201-13. doi: 10.1038/emboj.2011.380. Epub 2011 Oct 28. EMBO J. 2012. PMID: 22036947 Free PMC article.
CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells.
Poppensieker K, Otte DM, Schürmann B, Limmer A, Dresing P, Drews E, Schumak B, Klotz L, Raasch J, Mildner A, Waisman A, Scheu S, Knolle P, Förster I, Prinz M, Maier W, Zimmer A, Alferink J. Poppensieker K, et al. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3897-902. doi: 10.1073/pnas.1114153109. Epub 2012 Feb 21. Proc Natl Acad Sci U S A. 2012. PMID: 22355103 Free PMC article.
TNF-induced target cell killing by CTL activated through cross-presentation.
Wohlleber D, Kashkar H, Gärtner K, Frings MK, Odenthal M, Hegenbarth S, Börner C, Arnold B, Hämmerling G, Nieswandt B, van Rooijen N, Limmer A, Cederbrant K, Heikenwalder M, Pasparakis M, Protzer U, Dienes HP, Kurts C, Krönke M, Knolle PA. Wohlleber D, et al. Among authors: knolle pa. Cell Rep. 2012 Sep 27;2(3):478-87. doi: 10.1016/j.celrep.2012.08.001. Epub 2012 Aug 30. Cell Rep. 2012. PMID: 22939982 Free article.
Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity.
Böttcher JP, Schanz O, Wohlleber D, Abdullah Z, Debey-Pascher S, Staratschek-Jox A, Höchst B, Hegenbarth S, Grell J, Limmer A, Atreya I, Neurath MF, Busch DH, Schmitt E, van Endert P, Kolanus W, Kurts C, Schultze JL, Diehl L, Knolle PA. Böttcher JP, et al. Among authors: knolle pa. Cell Rep. 2013 Mar 28;3(3):779-95. doi: 10.1016/j.celrep.2013.02.008. Epub 2013 Mar 14. Cell Rep. 2013. PMID: 23499443 Free article.
Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.
Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA. Huang LR, et al. Among authors: knolle pa. Nat Immunol. 2013 Jun;14(6):574-83. doi: 10.1038/ni.2573. Epub 2013 Apr 14. Nat Immunol. 2013. PMID: 23584070
253 results