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52 results
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Vitamin D supplementation for sickle cell disease.
Soe HHK, Abas AB, Than NN, Ni H, Singh J, Said ARBM, Osunkwo I. Soe HHK, et al. Among authors: osunkwo i. Cochrane Database Syst Rev. 2020 May 28;5(5):CD010858. doi: 10.1002/14651858.CD010858.pub3. Cochrane Database Syst Rev. 2020. PMID: 32462740 Free PMC article.
Clinical trial implementation and recruitment: lessons learned from the early closure of a randomized clinical trial.
Peters-Lawrence MH, Bell MC, Hsu LL, Osunkwo I, Seaman P, Blackwood M, Guillaume E, Bellevue R, Krishnamurti L, Smith WR, Dampier CD, Minniti CP; Sickle Cell Disease Clinical Research Network (SCDCRN). Peters-Lawrence MH, et al. Contemp Clin Trials. 2012 Mar;33(2):291-7. doi: 10.1016/j.cct.2011.11.018. Epub 2011 Dec 2. Contemp Clin Trials. 2012. PMID: 22155024 Free PMC article. Clinical Trial.
A pilot study of tacrolimus and mycophenolate mofetil graft-versus-host disease prophylaxis in childhood and adolescent allogeneic stem cell transplant recipients.
Osunkwo I, Bessmertny O, Harrison L, Cheung YK, Van de Ven C, del Toro G, Garvin J, George D, Bradley MB, Wolownik K, Wischhover C, Levy J, Skerrett D, Cairo MS. Osunkwo I, et al. Biol Blood Marrow Transplant. 2004 Apr;10(4):246-58. doi: 10.1016/j.bbmt.2003.11.005. Biol Blood Marrow Transplant. 2004. PMID: 15077223 Clinical Trial.
Vitamin D supplementation for sickle cell disease.
Soe HH, Abas AB, Than NN, Ni H, Singh J, Said AR, Osunkwo I. Soe HH, et al. Among authors: osunkwo i. Cochrane Database Syst Rev. 2017 Jan 20;1(1):CD010858. doi: 10.1002/14651858.CD010858.pub2. Cochrane Database Syst Rev. 2017. PMID: 28105733 Free PMC article. Updated. Review.
High dose vitamin D therapy for chronic pain in children and adolescents with sickle cell disease: results of a randomized double blind pilot study.
Osunkwo I, Ziegler TR, Alvarez J, McCracken C, Cherry K, Osunkwo CE, Ofori-Acquah SF, Ghosh S, Ogunbobode A, Rhodes J, Eckman JR, Dampier C, Tangpricha V. Osunkwo I, et al. Br J Haematol. 2012 Oct;159(2):211-5. doi: 10.1111/bjh.12019. Epub 2012 Aug 28. Br J Haematol. 2012. PMID: 22924607 Free PMC article. Clinical Trial.
Optimizing the management of chronic pain in sickle cell disease.
Osunkwo I, O'Connor HF, Saah E. Osunkwo I, et al. Hematology Am Soc Hematol Educ Program. 2020 Dec 4;2020(1):562-569. doi: 10.1182/hematology.2020000143. Hematology Am Soc Hematol Educ Program. 2020. PMID: 33275672 Free PMC article. Review.
Chronic kidney disease and albuminuria in children with sickle cell disease.
McPherson Yee M, Jabbar SF, Osunkwo I, Clement L, Lane PA, Eckman JR, Guasch A. McPherson Yee M, et al. Among authors: osunkwo i. Clin J Am Soc Nephrol. 2011 Nov;6(11):2628-33. doi: 10.2215/CJN.01600211. Epub 2011 Sep 22. Clin J Am Soc Nephrol. 2011. PMID: 21940843 Free PMC article.
Treatment for osteoporosis in people with ß-thalassaemia.
Bhardwaj A, Swe KM, Sinha NK, Osunkwo I. Bhardwaj A, et al. Among authors: osunkwo i. Cochrane Database Syst Rev. 2016 Mar 10;3:CD010429. doi: 10.1002/14651858.CD010429.pub2. Cochrane Database Syst Rev. 2016. PMID: 26964506 Review.
A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R, Tran LT, Razon RL, Stark CW, Neumayr LD, Vichinsky EP; Investigators of the Phase 3 Trial of l-Glutamine in Sickle Cell Disease. Niihara Y, et al. Among authors: osunkwo i. N Engl J Med. 2018 Jul 19;379(3):226-235. doi: 10.1056/NEJMoa1715971. N Engl J Med. 2018. PMID: 30021096 Clinical Trial.
American Society of Hematology 2019 guidelines for sickle cell disease: cardiopulmonary and kidney disease.
Liem RI, Lanzkron S, D Coates T, DeCastro L, Desai AA, Ataga KI, Cohen RT, Haynes J, Osunkwo I, Lebensburger JD, Lash JP, Wun T, Verhovsek M, Ontala E, Blaylark R, Alahdab F, Katabi A, Mustafa RA. Liem RI, et al. Among authors: osunkwo i. Blood Adv. 2019 Dec 10;3(23):3867-3897. doi: 10.1182/bloodadvances.2019000916. Blood Adv. 2019. PMID: 31794601 Free PMC article.
Building access to care in adult sickle cell disease: defining models of care, essential components, and economic aspects.
Kanter J, Smith WR, Desai PC, Treadwell M, Andemariam B, Little J, Nugent D, Claster S, Manwani DG, Baker J, Strouse JJ, Osunkwo I, Stewart RW, King A, Shook LM, Roberts JD, Lanzkron S. Kanter J, et al. Among authors: osunkwo i. Blood Adv. 2020 Aug 25;4(16):3804-3813. doi: 10.1182/bloodadvances.2020001743. Blood Adv. 2020. PMID: 32785684 Free PMC article.
Impact of sickle cell disease on patients' daily lives, symptoms reported, and disease management strategies: Results from the international Sickle Cell World Assessment Survey (SWAY).
Osunkwo I, Andemariam B, Minniti CP, Inusa BPD, El Rassi F, Francis-Gibson B, Nero A, Trimnell C, Abboud MR, Arlet JB, Colombatti R, de Montalembert M, Jain S, Jastaniah W, Nur E, Pita M, DeBonnett L, Ramscar N, Bailey T, Rajkovic-Hooley O, James J. Osunkwo I, et al. Am J Hematol. 2021 Apr 1;96(4):404-417. doi: 10.1002/ajh.26063. Epub 2021 Feb 25. Am J Hematol. 2021. PMID: 33264445 Free PMC article.
Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: a phase III analgesic trial for hospitalized sickle cell patients with painful episodes.
Dampier CD, Smith WR, Kim HY, Wager CG, Bell MC, Minniti CP, Keefer J, Hsu L, Krishnamurti L, Mack AK, McClish D, McKinlay SM, Miller ST, Osunkwo I, Seaman P, Telen MJ, Weiner DL; Investigators of the Sickle Cell Disease Clinical Research Network (SCDCRN). Dampier CD, et al. Am J Hematol. 2011 Dec;86(12):E70-3. doi: 10.1002/ajh.22176. Epub 2011 Sep 22. Am J Hematol. 2011. PMID: 21953763 Free PMC article. Clinical Trial.
IMPROVE trial: a randomized controlled trial of patient-controlled analgesia for sickle cell painful episodes: rationale, design challenges, initial experience, and recommendations for future studies.
Dampier CD, Smith WR, Wager CG, Kim HY, Bell MC, Miller ST, Weiner DL, Minniti CP, Krishnamurti L, Ataga KI, Eckman JR, Hsu LL, McClish D, McKinlay SM, Molokie R, Osunkwo I, Smith-Whitley K, Telen MJ; Sickle Cell Disease Clinical Research Network (SCDCRN). Dampier CD, et al. Clin Trials. 2013 Apr;10(2):319-31. doi: 10.1177/1740774513475850. Clin Trials. 2013. PMID: 23539110 Free PMC article. Clinical Trial.
Microarchitectural and mechanical characterization of the sickle bone.
Green M, Akinsami I, Lin A, Banton S, Ghosh S, Chen B, Platt M, Osunkwo I, Ofori-Acquah S, Guldberg R, Barabino G. Green M, et al. J Mech Behav Biomed Mater. 2015 Aug;48:220-228. doi: 10.1016/j.jmbbm.2015.04.019. Epub 2015 Apr 24. J Mech Behav Biomed Mater. 2015. PMID: 25957113 Free PMC article.
Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and stroke.
Dowling MM, Quinn CT, Ramaciotti C, Kanter J, Osunkwo I, Inusa B, Iyer R, Kwiatkowski JL, Johnson C, Rhodes M, Owen W, Strouse JJ, Panepinto JA, Neumayr L, Sarnaik S, Plumb PA, Dlamini N, Kirkham F, Hynan LS; PFAST Investigators. Dowling MM, et al. Among authors: osunkwo i. Br J Haematol. 2017 Jan;176(2):300-308. doi: 10.1111/bjh.14391. Epub 2016 Oct 21. Br J Haematol. 2017. PMID: 27766637 Free PMC article.
Vitamin D deficiency and chronic pain in sickle cell disease.
Osunkwo I, Hodgman EI, Cherry K, Dampier C, Eckman J, Ziegler TR, Ofori-Acquah S, Tangpricha V. Osunkwo I, et al. Br J Haematol. 2011 May;153(4):538-40. doi: 10.1111/j.1365-2141.2010.08458.x. Epub 2011 Jan 31. Br J Haematol. 2011. PMID: 21275953 No abstract available.
International and Interdisciplinary Identification of Health Care Transition Outcomes.
Fair C, Cuttance J, Sharma N, Maslow G, Wiener L, Betz C, Porter J, McLaughlin S, Gilleland-Marchak J, Renwick A, Naranjo D, Jan S, Javalkar K, Ferris M; International and Interdisciplinary Health Care Transition Research Consortium. Fair C, et al. JAMA Pediatr. 2016 Mar;170(3):205-11. doi: 10.1001/jamapediatrics.2015.3168. JAMA Pediatr. 2016. PMID: 26619178 Free PMC article.
Therapeutic phlebotomy is safe in children with sickle cell anaemia and can be effective treatment for transfusional iron overload.
Aygun B, Mortier NA, Kesler K, Lockhart A, Schultz WH, Cohen AR, Alvarez O, Rogers ZR, Kwiatkowski JL, Miller ST, Sylvestre P, Iyer R, Lane PA, Ware RE; Stroke With Transfusions Changing to Hydroxyurea (SWiTCH) Trial Investigators. Aygun B, et al. Br J Haematol. 2015 Apr;169(2):262-6. doi: 10.1111/bjh.13280. Epub 2015 Jan 22. Br J Haematol. 2015. PMID: 25612463 Free PMC article. Clinical Trial.
Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial.
Helton KJ, Adams RJ, Kesler KL, Lockhart A, Aygun B, Driscoll C, Heeney MM, Jackson SM, Krishnamurti L, Miller ST, Sarnaik SA, Schultz WH, Ware RE; SWiTCH Investigators. Helton KJ, et al. Blood. 2014 Aug 7;124(6):891-8. doi: 10.1182/blood-2013-12-545186. Epub 2014 Jun 9. Blood. 2014. PMID: 24914136 Free PMC article. Clinical Trial.
Pain and other non-neurological adverse events in children with sickle cell anemia and previous stroke who received hydroxyurea and phlebotomy or chronic transfusions and chelation: results from the SWiTCH clinical trial.
Alvarez O, Yovetich NA, Scott JP, Owen W, Miller ST, Schultz W, Lockhart A, Aygun B, Flanagan J, Bonner M, Mueller BU, Ware RE; Investigators of the Stroke With Transfusions Changing to Hydroxyurea Clinical Trial (SWiTCH). Alvarez O, et al. Am J Hematol. 2013 Nov;88(11):932-8. doi: 10.1002/ajh.23547. Epub 2013 Aug 30. Am J Hematol. 2013. PMID: 23861242 Free PMC article. Clinical Trial.
Stroke With Transfusions Changing to Hydroxyurea (SWiTCH).
Ware RE, Helms RW; SWiTCH Investigators. Ware RE, et al. Blood. 2012 Apr 26;119(17):3925-32. doi: 10.1182/blood-2011-11-392340. Epub 2012 Feb 7. Blood. 2012. PMID: 22318199 Free PMC article. Clinical Trial.
Effect of hydroxyurea treatment on renal function parameters: results from the multi-center placebo-controlled BABY HUG clinical trial for infants with sickle cell anemia.
Alvarez O, Miller ST, Wang WC, Luo Z, McCarville MB, Schwartz GJ, Thompson B, Howard T, Iyer RV, Rana SR, Rogers ZR, Sarnaik SA, Thornburg CD, Ware RE; BABY HUG Investigators. Alvarez O, et al. Pediatr Blood Cancer. 2012 Oct;59(4):668-74. doi: 10.1002/pbc.24100. Epub 2012 Jan 31. Pediatr Blood Cancer. 2012. PMID: 22294512 Free PMC article. Clinical Trial.
Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG).
Wang WC, Ware RE, Miller ST, Iyer RV, Casella JF, Minniti CP, Rana S, Thornburg CD, Rogers ZR, Kalpatthi RV, Barredo JC, Brown RC, Sarnaik SA, Howard TH, Wynn LW, Kutlar A, Armstrong FD, Files BA, Goldsmith JC, Waclawiw MA, Huang X, Thompson BW; BABY HUG investigators. Wang WC, et al. Lancet. 2011 May 14;377(9778):1663-72. doi: 10.1016/S0140-6736(11)60355-3. Lancet. 2011. PMID: 21571150 Free PMC article. Clinical Trial.
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