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15,376 results

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Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.
Li JH, Brenner LN, Kaur V, Figueroa K, Schroeder P, Huerta-Chagoya A; MAGIC Investigators; Diabetes Prevention Program (DPP) Research Group; Udler MS, Leong A, Mercader JM, Florez JC. Li JH, et al. Diabetologia. 2023 Jul;66(7):1260-1272. doi: 10.1007/s00125-023-05922-7. Epub 2023 May 26. Diabetologia. 2023. PMID: 37233759
LAT1 enables T cell activation under inflammatory conditions.
Ogbechi J, Wright HL, Balint S, Topping LM, Kristina Z, Huang YS, Pantazi E, Swart M, Windell D, Marin E, Wempe MF, Endou H, Thomas AM, Filer A, Stone TW, Clarke AJ, Dustin ML, Williams RO. Ogbechi J, et al. Among authors: williams ro. J Autoimmun. 2023 May 23;138:103031. doi: 10.1016/j.jaut.2023.103031. Online ahead of print. J Autoimmun. 2023. PMID: 37229811
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Gong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B. Gong GQ, et al. Among authors: williams rl. Nature. 2023 Jun;618(7963):159-168. doi: 10.1038/s41586-023-05972-2. Epub 2023 May 24. Nature. 2023. PMID: 37225977
A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.
de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts A, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Woods LCS, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MMR, Williams RW, Li JZ, Chen H. de Jong TV, et al. Among authors: williams rw. bioRxiv. 2023 Apr 14:2023.04.13.536694. doi: 10.1101/2023.04.13.536694. Preprint. bioRxiv. 2023. PMID: 37214860 Free PMC article.
A Datasheet for the INSIGHT Birmingham, Solihull, and Black Country Diabetic Retinopathy Screening Dataset.
Kale AU, Mills A, Guggenheim E, Gee D, Bodza S, Anumakonda A, Doal R, Williams R, Gallier S, Lee WH, Galsworthy P, Benning M, Fanning H, Keane PA, Denniston AK, Mollan SP. Kale AU, et al. Among authors: williams r. Ophthalmol Sci. 2023 Feb 26;3(3):100293. doi: 10.1016/j.xops.2023.100293. eCollection 2023 Sep. Ophthalmol Sci. 2023. PMID: 37193316 Free PMC article.
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes.
McAllan L, Baranasic D, Villicaña S, Brown S, Zhang W, Lehne B, Adamo M, Jenkinson A, Elkalaawy M, Mohammadi B, Hashemi M, Fernandes N, Lambie N, Williams R, Christiansen C, Yang Y, Zudina L, Lagou V, Tan S, Castillo-Fernandez J, King JWD, Soong R, Elliott P, Scott J, Prokopenko I, Cebola I, Loh M, Lenhard B, Batterham RL, Bell JT, Chambers JC, Kooner JS, Scott WR. McAllan L, et al. Among authors: williams r. Nat Commun. 2023 May 15;14(1):2784. doi: 10.1038/s41467-023-38439-z. Nat Commun. 2023. PMID: 37188674 Free PMC article.
Integrating Tobacco Use Assessment and Treatment in the Oncology Setting: Quality Improvement Results from the Georgetown Lombardi Smoking Treatment and Recovery Program.
Taylor KL, Webster MA, Philips JG, Whealan JM, Lobo T, Davis KM, Breece CJ, Wheeley JR, Childs JE, Le AQ, Williams RM, Veytsman IG, Kim C. Taylor KL, et al. Among authors: williams rm. Curr Oncol. 2023 Mar 28;30(4):3755-3775. doi: 10.3390/curroncol30040285. Curr Oncol. 2023. PMID: 37185398 Free PMC article.
The Impact of Pre-Operative Anaemia on One Year Amputation Free Survival and Re-Admissions in Patients Undergoing Vascular Surgery for Peripheral Arterial Disease: a National Vascular Registry Study.
Birmpili P, Cromwell DA, Li Q, Johal AS, Atkins E, Waton S, Pherwani AD, Williams R, Richards T, Nandhra S. Birmpili P, et al. Among authors: williams r. Eur J Vasc Endovasc Surg. 2023 May 9:S1078-5884(23)00364-7. doi: 10.1016/j.ejvs.2023.05.003. Online ahead of print. Eur J Vasc Endovasc Surg. 2023. PMID: 37169135 Free article.
Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery.
Edwards MR, Forbes G, Walker N, Morton DG, Mythen MG, Murray D, Anderson I, Mihaylova B, Thomson A, Taylor M, Hollyman M, Phillips R, Young K, Kahan BC, Pearse RM, Grocott MPW; FLO-ELA investigators. Edwards MR, et al. Trials. 2023 May 6;24(1):313. doi: 10.1186/s13063-023-07275-3. Trials. 2023. PMID: 37149623 Free PMC article.
Injury prevention strategies at the 2019 FIFA Women's World Cup display a multifactorial approach and highlight subjective wellness measurements.
Saltzman EB, Levin JM, Dagher AB, Messer M, Kimball R, Lohnes J, Mandelbaum BR, Williams RJ 3rd, Amendola A, Chiampas G, Lau BC. Saltzman EB, et al. Among authors: williams rj 3rd. J ISAKOS. 2023 May 4:S2059-7754(23)00473-X. doi: 10.1016/j.jisako.2023.04.007. Online ahead of print. J ISAKOS. 2023. PMID: 37146689 Free article.
Updated APSA Guidelines for the Management of Blunt Liver and Spleen Injuries.
Williams RF, Grewal H, Jamshidi R, Naik-Mathuria B, Price M, Russell RT, Vogel A, Notrica DM, Stylianos S, Petty J. Williams RF, et al. J Pediatr Surg. 2023 Mar 23:S0022-3468(23)00225-7. doi: 10.1016/j.jpedsurg.2023.03.012. Online ahead of print. J Pediatr Surg. 2023. PMID: 37117078 Review.
A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome.
Walker R, Mahmood K, Joo JE, Clendenning M, Georgeson P, Como J, Joseland S, Preston SG, Antill Y, Austin R, Boussioutas A, Bowman M, Burke J, Campbell A, Daneshvar S, Edwards E, Gleeson M, Goodwin A, Harris MT, Henderson A, Higgins M, Hopper JL, Hutchinson RA, Ip E, Isbister J, Kasem K, Marfan H, Milnes D, Ng A, Nichols C, O'Connell S, Pachter N, Pope BJ, Poplawski N, Ragunathan A, Smyth C, Spigelman A, Storey K, Susman R, Taylor JA, Warwick L, Wilding M, Williams R, Win AK, Walsh MD, Macrae FA, Jenkins MA, Rosty C, Winship IM, Buchanan DD; Family Cancer Clinics of Australia. Walker R, et al. Among authors: williams r. J Transl Med. 2023 Apr 26;21(1):282. doi: 10.1186/s12967-023-04143-1. J Transl Med. 2023. PMID: 37101184 Free PMC article.
Risk for Infection in Humans after Exposure to Birds Infected with Highly Pathogenic Avian Influenza A(H5N1) Virus, United States, 2022.
Kniss K, Sumner KM, Tastad KJ, Lewis NM, Jansen L, Julian D, Reh M, Carlson E, Williams R, Koirala S, Buss B, Donahue M, Palm J, Kollmann L, Holzbauer S, Levine MZ, Davis T, Barnes JR, Flannery B, Brammer L, Fry A. Kniss K, et al. Among authors: williams r. Emerg Infect Dis. 2023 Jun;29(6):1215-1219. doi: 10.3201/eid2906.230103. Epub 2023 Apr 24. Emerg Infect Dis. 2023. PMID: 37095080 Free PMC article.
L-DOPA increases slow-wave sleep duration and selectively modulates memory persistence in older adults.
Isotalus HK, Carr WJ, Blackman J, Averill GG, Radtke O, Selwood J, Williams R, Ford E, McCullagh L, McErlane J, O'Donnell C, Durant C, Bartsch U, Jones MW, Muñoz-Neira C, Wearn AR, Grogan JP, Coulthard EJ. Isotalus HK, et al. Among authors: williams r. Front Behav Neurosci. 2023 Apr 5;17:1096720. doi: 10.3389/fnbeh.2023.1096720. eCollection 2023. Front Behav Neurosci. 2023. PMID: 37091594 Free PMC article.
First Measurement of Λ Electroproduction off Nuclei in the Current and Target Fragmentation Regions.
Chetry T, El Fassi L, Brooks WK, Dupré R, El Alaoui A, Hafidi K, Achenbach P, Adhikari KP, Akbar Z, Armstrong WR, Arratia M, Atac H, Avakian H, Baashen L, Baltzell NA, Barion L, Bashkanov M, Battaglieri M, Bedlinskiy I, Benkel B, Benmokhtar F, Bianconi A, Biselli AS, Bondi M, Booth WA, Bossù F, Boiarinov S, Brinkmann KT, Briscoe WJ, Bulumulla D, Burkert VD, Carman DS, Carvajal JC, Celentano A, Chatagnon P, Chesnokov V, Ciullo G, Cole PL, Contalbrigo M, Costantini G, D'Angelo A, Dashyan N, De Vita R, Defurne M, Deur A, Diehl S, Djalali C, Egiyan H, Elouadrhiri L, Eugenio P, Fegan S, Filippi A, Gavalian G, Ghandilyan Y, Gilfoyle GP, Glazier DI, Golubenko AA, Gosta G, Gothe RW, Griffioen KA, Guidal M, Guo L, Hakobyan H, Hattawy M, Hayward TB, Heddle D, Hobart A, Holtrop M, Ilieva Y, Ireland DG, Isupov EL, Jenkins D, Jo HS, Kabir ML, Khanal A, Khandaker M, Kim A, Kim W, Klein FJ, Kripko A, Kubarovsky V, Lagerquist V, Lanza L, Leali M, Lee S, Lenisa P, Li X, Livingston K, MacGregor IJD, Marchand D, Mascagna V, McKinnon B, McLauchlin C, Meziani ZE, Migliorati S, Mineeva T, Mirazita M, Mokeev V, Munoz Camacho C, Nadel-Turonski P, Neupane K, Niccolai S, Nicol M, Niculescu G, Osipenko M, O… See abstract for full author list ➔ Chetry T, et al. Among authors: williams r. Phys Rev Lett. 2023 Apr 7;130(14):142301. doi: 10.1103/PhysRevLett.130.142301. Phys Rev Lett. 2023. PMID: 37084423
Energy budget diagnosis of changing climate feedback.
Cael BB, Bloch-Johnson J, Ceppi P, Fredriksen HB, Goodwin P, Gregory JM, Smith CJ, Williams RG. Cael BB, et al. Sci Adv. 2023 Apr 21;9(16):eadf9302. doi: 10.1126/sciadv.adf9302. Epub 2023 Apr 21. Sci Adv. 2023. PMID: 37083537 Free PMC article.
Mixed-methods feasibility study to inform a randomised controlled trial of proton pump inhibitors to reduce strictures following neonatal surgery for oesophageal atresia.
Mitchell TK, Hall NJ, Yardley I, Cole C, Hardy P, King A, Murray D, Nuthall E, Roehr C, Stanbury K, Williams R, Pearce J, Woolfall K. Mitchell TK, et al. Among authors: williams r. BMJ Open. 2023 Apr 20;13(4):e066070. doi: 10.1136/bmjopen-2022-066070. BMJ Open. 2023. PMID: 37080617 Free PMC article.
Crystalloid Volume is Associated with Short Term Morbidity in Children with Severe Traumatic Brain Injury: An Eastern Association for the Surgery of Trauma Multicenter Trial Post-Hoc Analysis.
MacArthur TA, Vogel AM, Glasgow AE, Moody S, Kotagal M, Williams RF, Kayton ML, Alberto EC, Burd RS, Schroeppel TJ, Baerg JE, Munoz A, Rothstein WB, Boomer LA, Campion EM, Robinson C, Nygaard RM, Richardson CJ, Garcia DI, Streck CJ, Gaffley M, Petty JK, Ryan M, Pandya S, Russell RT, Yorkgitis BK, Mull J, Pence J, Santore MT, Klinkner DB, Safford SD, Trevilian T, Jensen AR, Mooney DP, Ketha B, Dassinger MS 3rd, Goldenberg-Sandau A, Falcone RA, Polites SF. MacArthur TA, et al. Among authors: williams rf. J Trauma Acute Care Surg. 2023 Apr 19. doi: 10.1097/TA.0000000000004013. Online ahead of print. J Trauma Acute Care Surg. 2023. PMID: 37072882
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