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Modulation of anxiety through blockade of anandamide hydrolysis.
Kathuria S, Gaetani S, Fegley D, Valiño F, Duranti A, Tontini A, Mor M, Tarzia G, La Rana G, Calignano A, Giustino A, Tattoli M, Palmery M, Cuomo V, Piomelli D. Kathuria S, et al. Among authors: calignano a. Nat Med. 2003 Jan;9(1):76-81. doi: 10.1038/nm803. Epub 2002 Dec 2. Nat Med. 2003. PMID: 12461523
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice.
Russo R, Loverme J, La Rana G, Compton TR, Parrott J, Duranti A, Tontini A, Mor M, Tarzia G, Calignano A, Piomelli D. Russo R, et al. Among authors: calignano a. J Pharmacol Exp Ther. 2007 Jul;322(1):236-42. doi: 10.1124/jpet.107.119941. Epub 2007 Apr 5. J Pharmacol Exp Ther. 2007. PMID: 17412883
Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice.
D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Raso GM, Cuzzocrea S, Lo Verme J, Piomelli D, Meli R, Calignano A. D'Agostino G, et al. Among authors: calignano a. J Pharmacol Exp Ther. 2007 Sep;322(3):1137-43. doi: 10.1124/jpet.107.123265. Epub 2007 Jun 12. J Pharmacol Exp Ther. 2007. PMID: 17565008
Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism.
Clapper JR, Moreno-Sanz G, Russo R, Guijarro A, Vacondio F, Duranti A, Tontini A, Sanchini S, Sciolino NR, Spradley JM, Hohmann AG, Calignano A, Mor M, Tarzia G, Piomelli D. Clapper JR, et al. Among authors: calignano a. Nat Neurosci. 2010 Oct;13(10):1265-70. doi: 10.1038/nn.2632. Epub 2010 Sep 19. Nat Neurosci. 2010. PMID: 20852626 Free PMC article.
171 results