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ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging.
Snieckute G, Ryder L, Vind AC, Wu Z, Arendrup FS, Stoneley M, Chamois S, Martinez-Val A, Leleu M, Dreos R, Russell A, Gay DM, Genzor AV, Choi BS, Basse AL, Sass F, Dall M, Dollet LCM, Blasius M, Willis AE, Lund AH, Treebak JT, Olsen JV, Poulsen SS, Pownall ME, Jensen BAH, Clemmensen C, Gerhart-Hines Z, Gatfield D, Bekker-Jensen S. Snieckute G, et al. Among authors: chamois s. Science. 2023 Dec 8;382(6675):eadf3208. doi: 10.1126/science.adf3208. Epub 2023 Dec 8. Science. 2023. PMID: 38060659
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S. Snieckute G, et al. Among authors: chamois s. Cell Metab. 2022 Dec 6;34(12):2036-2046.e8. doi: 10.1016/j.cmet.2022.10.011. Epub 2022 Nov 15. Cell Metab. 2022. PMID: 36384144 Free PMC article.
Research priorities to improve the management of acute malnutrition in infants aged less than six months (MAMI).
Angood C, McGrath M, Mehta S, Mwangome M, Lung'aho M, Roberfroid D, Perry A, Wilkinson C, Israel AD, Bizouerne C, Haider R, Seal A, Berkley JA, Kerac M; MAMI Working Group Collaborators. Angood C, et al. PLoS Med. 2015 Apr 21;12(4):e1001812. doi: 10.1371/journal.pmed.1001812. eCollection 2015 Apr. PLoS Med. 2015. PMID: 25898252 Free PMC article.