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Brain-Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease.
Sela M, Poley M, Mora-Raimundo P, Kagan S, Avital A, Kaduri M, Chen G, Adir O, Rozencweig A, Weiss Y, Sade O, Leichtmann-Bardoogo Y, Simchi L, Aga-Mizrachi S, Bell B, Yeretz-Peretz Y, Or AZ, Choudhary A, Rosh I, Cordeiro D, Cohen-Adiv S, Berdichevsky Y, Odeh A, Shklover J, Shainsky-Roitman J, Schroeder JE, Hershkovitz D, Hasson P, Ashkenazi A, Stern S, Laviv T, Ben-Zvi A, Avital A, Ashery U, Maoz BM, Schroeder A. Sela M, et al. Adv Mater. 2023 Dec;35(51):e2304654. doi: 10.1002/adma.202304654. Epub 2023 Oct 27. Adv Mater. 2023. PMID: 37753928 Free PMC article.
Polymersomes with splenic avidity target red pulp myeloid cells for cancer immunotherapy.
Wauters AC, Scheerstra JF, van Leent MMT, Teunissen AJP, Priem B, Beldman TJ, Rother N, Duivenvoorden R, Prévot G, Munitz J, Toner YC, Deckers J, van Elsas Y, Mora-Raimundo P, Chen G, Nauta SA, Verschuur AVD, Griffioen AW, Schrijver DP, Anbergen T, Li Y, Wu H, Mason AF, van Stevendaal MHME, Kluza E, Post RAJ, Joosten LAB, Netea MG, Calcagno C, Fayad ZA, van der Meel R, Schroeder A, Abdelmohsen LKEA, Mulder WJM, van Hest JCM. Wauters AC, et al. Nat Nanotechnol. 2024 Nov;19(11):1735-1744. doi: 10.1038/s41565-024-01727-w. Epub 2024 Jul 31. Nat Nanotechnol. 2024. PMID: 39085390 Free PMC article.
Shank3 mutation impairs glutamate signaling and myelination in ASD mouse model and human iPSC-derived OPCs.
Fischer I, Shohat S, Leichtmann-Bardoogo Y, Nayak R, Wiener G, Rosh I, Shemen A, Tripathi U, Rokach M, Bar E, Hussein Y, Castro AC, Chen G, Soffer A, Schokoroy-Trangle S, Elad-Sfadia G, Assaf Y, Schroeder A, Monteiro P, Stern S, Maoz BM, Barak B. Fischer I, et al. Sci Adv. 2024 Oct 11;10(41):eadl4573. doi: 10.1126/sciadv.adl4573. Epub 2024 Oct 11. Sci Adv. 2024. PMID: 39392881 Free PMC article.
AI-Validated Brain Targeted mRNA Lipid Nanoparticles with Neuronal Tropism.
Sela M, Chen G, Kadosh H, Kagan T, Nicola R, Turutov S, Richtman Y, Zhige L, Albalak Menasherov MR, Kagan S, Schroeder T, Mora-Raimundo P, Kablan R, Egorov E, Odeh A, Abu-Raiya T, Ionita I, Freilich I, Kaneti G, Knani I, Arav Y, Leichtmann-Bardoogo Y, Tadmor K, Shklover J, Patriarchi T, Danino D, Hasson P, Ashery U, Zeisel A, Maoz BM, Laviv T, Radinsky K, Schroeder A. Sela M, et al. ACS Nano. 2025 Oct 21;19(41):36106-36128. doi: 10.1021/acsnano.4c15013. Epub 2025 Sep 16. ACS Nano. 2025. PMID: 40957853 Free PMC article.
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