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Direct visualization of native GSDMD pores reveals lipid-driven stabilization during pyroptosis.
Kappelhoff S, Holtmannspötter M, Schaefer SL, Margheritis EG, Asik ÖD, Gehle N, Veit H, Danial JSH, Franzkoch R, Strauss S, Alvelid J, Koerfer A, Eggeling C, Psathaki OE, Jungmann R, Kurre R, Hummer G, Piehler J, Cosentino K. Kappelhoff S, et al. Among authors: cosentino k. Sci Adv. 2026 Jul 10;12(28):eaee4587. doi: 10.1126/sciadv.aee4587. Epub 2026 Jul 10. Sci Adv. 2026. PMID: 42430474 Free PMC article.
Towards a molecular and structural definition of cell death.
Arama E, Cosentino K, Czabotar PE, Gan B, Hartland E, Jiang X, Kagan JC, Nagata S, Schroder K, Sun L, Xu D, Yuan J. Arama E, et al. Among authors: cosentino k. Nat Struct Mol Biol. 2025 Oct;32(10):1854-1858. doi: 10.1038/s41594-025-01646-x. Nat Struct Mol Biol. 2025. PMID: 40968156 No abstract available.
New insights into Gasdermin D pore formation.
Kappelhoff S, Margheritis EG, Cosentino K. Kappelhoff S, et al. Among authors: cosentino k. Biochem Soc Trans. 2024 Apr 24;52(2):681-692. doi: 10.1042/BST20230549. Biochem Soc Trans. 2024. PMID: 38497302 Review.
38 results