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Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC.
Swartzel JC, Bond MJ, Pintado-Urbanc AP, Daftary M, Krone MW, Douglas T, Carder EJ, Zimmer JT, Maeda T, Simon MD, Crews CM. Swartzel JC, et al. Among authors: douglas t. ACS Chem Biol. 2022 Jul 15;17(7):1789-1798. doi: 10.1021/acschembio.2c00145. Epub 2022 Jun 24. ACS Chem Biol. 2022. PMID: 35749470 Free PMC article.
Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma.
Zhang J, Ong W, Rasnitsyn A, Gonzalez RD, Lopez Gutierrez R, Balin P, Saadeldin A, Wu X, Vladoiu MC, Santa-Maria Lopez V, Gonzalez-Salinas F, Yadav N, Mohanakrishnan D, Boosi Narayana Rao K, Mooli RGR, Najem H, Pacheco S, Kharas K, Richman C, Przelicki D, Wang EY, Su H, Curry RN, Yang R, Kameda-Smith MM, Livingston B, Scott D, Luo Z, Xia M, Abeysundara N, Erickson AW, Mankahla N, Hu LZ, Pan C, Suarez R, Huang N, Wu Y, Wang H, Douglas T, Pallota J, Hébert S, Ng K, Mantione K, Whetstone H, Maan H, Lakkis H, Lee J, Ramakrishnan SK, Pei Y, Tang Y, Lin FY, Aldave G, Gallo M, Friedlander RM, Notta F, Donovan LK, Chintagumpala M, Wang B, Li Y, De Carvalho DD, Zhang Z, Mao Y, Hua W, Eberhart C, Lucas CG, Venneti S, Sorensen PH, Delaidelli A, Li H, Zhou W, Kirk J, Tang DG, Jiang T, Liu H, Lathia JD, Suzuki H, Rich JN, Stein LD, Jabado N, Ramaswamy V, Lu QR, Heimberger AB, Daniels C, Michealraj KA, Kleinman CL, Taylor MD. Zhang J, et al. Among authors: douglas t. Nature. 2026 Apr;652(8110):763-773. doi: 10.1038/s41586-026-10264-6. Epub 2026 Mar 25. Nature. 2026. PMID: 41882358 Free PMC article.
Heparin-incorporated whey protein isolate-derived hydrogels with an intended dual function as snakebite wound dressings and drug delivery systems inhibit spitting cobra venom-induced cytotoxicity.
Gray MJ, Baines DK, De Castro G, Cobb T, Tyrrell LA, Hyam SJ, Smith AM, Casewell NR, Allinson SL, Douglas TEL, Hall SR. Gray MJ, et al. Among authors: douglas tel. Toxicon. 2026 Jun 1;275:109061. doi: 10.1016/j.toxicon.2026.109061. Epub 2026 Mar 10. Toxicon. 2026. PMID: 41819408
819 results