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CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, Yao D, Lee K, Kuo CJ, Jackson PK, Sweet-Cordero A, Kundaje A, Gentles AJ, Curtis C, Winslow MM, Bassik MC. Han K, et al. Among authors: dubreuil m. Nature. 2020 Apr;580(7801):136-141. doi: 10.1038/s41586-020-2099-x. Epub 2020 Mar 11. Nature. 2020. PMID: 32238925 Free PMC article.
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes.
Wainberg M, Kamber RA, Balsubramani A, Meyers RM, Sinnott-Armstrong N, Hornburg D, Jiang L, Chan J, Jian R, Gu M, Shcherbina A, Dubreuil MM, Spees K, Meuleman W, Snyder MP, Bassik MC, Kundaje A. Wainberg M, et al. Among authors: dubreuil mm. Nat Genet. 2021 May;53(5):638-649. doi: 10.1038/s41588-021-00840-z. Epub 2021 Apr 15. Nat Genet. 2021. PMID: 33859415 Free PMC article.
Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins.
Morgens DW, Chan C, Kane AJ, Weir NR, Li A, Dubreuil MM, Tsui CK, Hess GT, Lavertu A, Han K, Polyakov N, Zhou J, Handy EL, Alabi P, Dombroski A, Yao D, Altman RB, Sello JK, Denic V, Bassik MC. Morgens DW, et al. Among authors: dubreuil mm. Elife. 2019 Nov 1;8:e48434. doi: 10.7554/eLife.48434. Elife. 2019. PMID: 31674906 Free PMC article.
Centralized Interactive Phenomics Resource: an integrated online phenomics knowledgebase for health data users.
Honerlaw J, Ho YL, Fontin F, Murray M, Galloway A, Heise D, Connatser K, Davies L, Gosian J, Maripuri M, Russo J, Sangar R, Tanukonda V, Zielinski E, Dubreuil M, Zimolzak AJ, Panickan VA, Cheng SC, Whitbourne SB, Gagnon DR, Cai T, Liao KP, Ramoni RB, Gaziano JM, Muralidhar S, Cho K. Honerlaw J, et al. Among authors: dubreuil m. J Am Med Inform Assoc. 2024 Apr 19;31(5):1126-1134. doi: 10.1093/jamia/ocae042. J Am Med Inform Assoc. 2024. PMID: 38481028 Free PMC article.
151 results