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Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19.
Liu H, Iketani S, Zask A, Khanizeman N, Bednarova E, Forouhar F, Fowler B, Hong SJ, Mohri H, Nair MS, Huang Y, Tay NES, Lee S, Karan C, Resnick SJ, Quinn C, Li W, Shion H, Xia X, Daniels JD, Bartolo-Cruz M, Farina M, Rajbhandari P, Jurtschenko C, Lauber MA, McDonald T, Stokes ME, Hurst BL, Rovis T, Chavez A, Ho DD, Stockwell BR. Liu H, et al. Among authors: farina m. Nat Commun. 2022 Apr 7;13(1):1891. doi: 10.1038/s41467-022-29413-2. Nat Commun. 2022. PMID: 35393402 Free PMC article.
Novel Probucol Analogue, 4,4'-Diselanediylbis (2,6-Di-tert-Butylphenol), Prevents Oxidative Glutamate Neurotoxicity In Vitro and Confers Neuroprotection in a Rodent Model of Ischemic Stroke.
Jacques MT, de Souza V, Barbosa FAR, Faria Santos Canto R, Lopes SC, Prediger RD, Braga AL, Aschner M, Farina M. Jacques MT, et al. Among authors: farina m. ACS Chem Neurosci. 2023 Aug 16;14(16):2857-2867. doi: 10.1021/acschemneuro.3c00138. Epub 2023 Jul 27. ACS Chem Neurosci. 2023. PMID: 37499207
Low toxicity of diphenyl diselenide in rabbits: a long-term study.
de Bem AF, de Lima Portella R, Farina M, Perottoni J, Paixão MW, Nogueira CW, Teixeira Rocha JB. de Bem AF, et al. Among authors: farina m. Basic Clin Pharmacol Toxicol. 2007 Jul;101(1):47-55. doi: 10.1111/j.1742-7843.2007.00073.x. Basic Clin Pharmacol Toxicol. 2007. PMID: 17577316 Free article.
920 results