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Page 1
Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice.
Wen Z, Rajagopalan A, Flietner ED, Yun G, Chesi M, Furumo Q, Burns RT, Papadas A, Ranheim EA, Pagenkopf AC, Morrow ZT, Finn R, Zhou Y, Li S, You X, Jensen J, Yu M, Cicala A, Menting J, Mitsiades CS, Callander NS, Bergsagel PL, Wang D, Asimakopoulos F, Zhang J. Wen Z, et al. Among authors: flietner ed. Blood. 2021 Jan 7;137(1):61-74. doi: 10.1182/blood.2020007156. Blood. 2021. PMID: 32640012 Free PMC article.
Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation.
You X, Liu F, Binder M, Vedder A, Lasho T, Wen Z, Gao X, Flietner E, Rajagopalan A, Zhou Y, Finke C, Mangaonkar A, Liao R, Kong G, Ranheim EA, Droin N, Hunter AM, Nikolaev S, Balasis M, Abdel-Wahab O, Levine RL, Will B, Nadiminti KVG, Yang D, Geissler K, Solary E, Xu W, Padron E, Patnaik MM, Zhang J. You X, et al. Among authors: flietner e. Blood. 2022 Feb 17;139(7):1066-1079. doi: 10.1182/blood.2021012519. Blood. 2022. PMID: 34699595 Free PMC article.
Versican proteolysis predicts immune effector infiltration and post-transplant survival in myeloma.
Dhakal B, Pagenkopf A, Mushtaq MU, Cunningham AM, Flietner E, Morrow Z, Papadas A, Hope C, Leith C, Hematti P, Hari P, Callander NS, Asimakopoulos F. Dhakal B, et al. Among authors: flietner e. Leuk Lymphoma. 2019 Oct;60(10):2558-2562. doi: 10.1080/10428194.2019.1585836. Epub 2019 Mar 8. Leuk Lymphoma. 2019. PMID: 30845856 Free PMC article. No abstract available.
Ponatinib sensitizes myeloma cells to MEK inhibition in the high-risk VQ model.
Flietner E, Wen Z, Rajagopalan A, Jung O, Watkins L, Wiesner J, You X, Zhou Y, Sun Y, Kingstad-Bakke B, Callander NS, Rapraeger A, Suresh M, Asimakopoulos F, Zhang J. Flietner E, et al. Sci Rep. 2022 Jun 23;12(1):10616. doi: 10.1038/s41598-022-14114-z. Sci Rep. 2022. PMID: 35739276 Free PMC article.
Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment.
Papadas A, Deb G, Cicala A, Officer A, Hope C, Pagenkopf A, Flietner E, Morrow ZT, Emmerich P, Wiesner J, Arauz G, Bansal V, Esbona K, Capitini CM, Matkowskyj KA, Deming DA, Politi K, Abrams SI, Harismendy O, Asimakopoulos F. Papadas A, et al. Among authors: flietner e. Cell Rep. 2022 Aug 16;40(7):111201. doi: 10.1016/j.celrep.2022.111201. Cell Rep. 2022. PMID: 35977482 Free PMC article.