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Severe COVID-19 is associated with hyperactivation of the alternative complement pathway.
Boussier J, Yatim N, Marchal A, Hadjadj J, Charbit B, El Sissy C, Carlier N, Pène F, Mouthon L, Tharaux PL, Bergeron A, Smadja DM, Rieux-Laucat F, Duffy D, Kernéis S, Frémeaux-Bacchi V, Terrier B. Boussier J, et al. J Allergy Clin Immunol. 2022 Feb;149(2):550-556.e2. doi: 10.1016/j.jaci.2021.11.004. Epub 2021 Nov 17. J Allergy Clin Immunol. 2022. PMID: 34800432 Free PMC article.
Complement C5 inhibition in patients with COVID-19 - a promising target?
Peffault de Latour R, Bergeron A, Lengline E, Dupont T, Marchal A, Galicier L, de Castro N, Bondeelle L, Darmon M, Dupin C, Dumas G, Leguen P, Madelaine I, Chevret S, Molina JM, Azoulay E, Fremeaux-Bacchi V, Core Group. Peffault de Latour R, et al. Haematologica. 2020 Dec 1;105(12):2847-2850. doi: 10.3324/haematol.2020.260117. Haematologica. 2020. PMID: 33256385 Free PMC article. No abstract available.
Eculizumab and drug-induced haemolytic-uraemic syndrome.
Faguer S, Huart A, Frémeaux-Bacchi V, Ribes D, Chauveau D. Faguer S, et al. Clin Kidney J. 2013 Oct;6(5):484-5. doi: 10.1093/ckj/sft078. Epub 2013 Sep 5. Clin Kidney J. 2013. PMID: 26120441 Free PMC article.
Insights from the use in clinical practice of eculizumab in adult patients with atypical hemolytic uremic syndrome affecting the native kidneys: an analysis of 19 cases.
Fakhouri F, Delmas Y, Provot F, Barbet C, Karras A, Makdassi R, Courivaud C, Rifard K, Servais A, Allard C, Besson V, Cousin M, Châtelet V, Goujon JM, Coindre JP, Laurent G, Loirat C, Frémeaux-Bacchi V. Fakhouri F, et al. Am J Kidney Dis. 2014 Jan;63(1):40-8. doi: 10.1053/j.ajkd.2013.07.011. Epub 2013 Sep 8. Am J Kidney Dis. 2014. PMID: 24021908
362 results