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141 results

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Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity.
Tutas J, Tolve M, Özer-Yildiz E, Ickert L, Klein I, Silverman Q, Liebsch F, Dethloff F, Giavalisco P, Endepols H, Georgomanolis T, Neumaier B, Drzezga A, Schwarz G, Thorens B, Gatto G, Frezza C, Kononenko NL. Tutas J, et al. Among authors: giavalisco p. Nat Metab. 2025 Jan 15. doi: 10.1038/s42255-024-01196-4. Online ahead of print. Nat Metab. 2025. PMID: 39815080
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen NC, Papies J, Bajaj T, Emanuel J, Dethloff F, Chua RL, Trimpert J, Heinemann N, Niemeyer C, Weege F, Hönzke K, Aschman T, Heinz DE, Weckmann K, Ebert T, Zellner A, Lennarz M, Wyler E, Schroeder S, Richter A, Niemeyer D, Hoffmann K, Meyer TF, Heppner FL, Corman VM, Landthaler M, Hocke AC, Morkel M, Osterrieder N, Conrad C, Eils R, Radbruch H, Giavalisco P, Drosten C, Müller MA. Gassen NC, et al. Among authors: giavalisco p. Nat Commun. 2021 Jun 21;12(1):3818. doi: 10.1038/s41467-021-24007-w. Nat Commun. 2021. PMID: 34155207 Free PMC article.
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity.
Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T. Sprenger HG, et al. Among authors: giavalisco p. Nat Metab. 2021 May;3(5):636-650. doi: 10.1038/s42255-021-00385-9. Epub 2021 Apr 26. Nat Metab. 2021. PMID: 33903774 Free PMC article.
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity.
Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG. Jiang S, et al. Among authors: giavalisco p. Nat Metab. 2024 Jun;6(6):1024-1035. doi: 10.1038/s42255-024-01038-3. Epub 2024 Apr 30. Nat Metab. 2024. PMID: 38689023 Free PMC article.
GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function.
Timper K, Del Río-Martín A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, Horvath TL, Kloppenburg P, Backes H, Brüning JC. Timper K, et al. Among authors: giavalisco p. Cell Metab. 2020 Jun 2;31(6):1189-1205.e13. doi: 10.1016/j.cmet.2020.05.001. Epub 2020 May 19. Cell Metab. 2020. PMID: 32433922 Free PMC article.
Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling.
Gӧbel J, Engelhardt E, Pelzer P, Sakthivelu V, Jahn HM, Jevtic M, Folz-Donahue K, Kukat C, Schauss A, Frese CK, Giavalisco P, Ghanem A, Conzelmann KK, Motori E, Bergami M. Gӧbel J, et al. Among authors: giavalisco p. Cell Metab. 2020 Apr 7;31(4):791-808.e8. doi: 10.1016/j.cmet.2020.03.005. Epub 2020 Mar 26. Cell Metab. 2020. PMID: 32220306 Free PMC article.
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver.
Aich A, Boshnakovska A, Witte S, Gall T, Unthan-Fechner K, Yousefi R, Chowdhury A, Dahal D, Methi A, Kaufmann S, Silbern I, Prochazka J, Nichtova Z, Palkova M, Raishbrook M, Koubkova G, Sedlacek R, Tröder SE, Zevnik B, Riedel D, Michanski S, Möbius W, Ströbel P, Lüchtenborg C, Giavalisco P, Urlaub H, Fischer A, Brügger B, Jakobs S, Rehling P. Aich A, et al. Among authors: giavalisco p. Nat Commun. 2024 Aug 12;15(1):6914. doi: 10.1038/s41467-024-51109-y. Nat Commun. 2024. PMID: 39134548 Free PMC article.
141 results