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28 results
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Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito.
Garrood WT, Kranjc N, Petri K, Kim DY, Guo JA, Hammond AM, Morianou I, Pattanayak V, Joung JK, Crisanti A, Simoni A. Garrood WT, et al. Among authors: guo ja. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2004838117. doi: 10.1073/pnas.2004838117. Epub 2021 Apr 30. Proc Natl Acad Sci U S A. 2021. PMID: 34050017 Free PMC article.
Precise DNA cleavage using CRISPR-SpRYgests.
Christie KA, Guo JA, Silverstein RA, Doll RM, Mabuchi M, Stutzman HE, Lin J, Ma L, Walton RT, Pinello L, Robb GB, Kleinstiver BP. Christie KA, et al. Among authors: guo ja. Nat Biotechnol. 2022 Oct 6. doi: 10.1038/s41587-022-01492-y. Online ahead of print. Nat Biotechnol. 2022. PMID: 36203014
Genomic alterations predictive of poor clinical outcomes in pan-cancer.
Seldon CS, Meiyappan K, Hoffman H, Guo JA, Goel N, Hwang WL, Nguyen PL, Mahal BA, Alshalalfa M. Seldon CS, et al. Among authors: guo ja. Oncotarget. 2022 Sep 28;13:1069-1077. doi: 10.18632/oncotarget.28276. eCollection 2022. Oncotarget. 2022. PMID: 36187555 Free PMC article.
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.
Hwang WL, Jagadeesh KA, Guo JA, Hoffman HI, Yadollahpour P, Reeves JW, Mohan R, Drokhlyansky E, Van Wittenberghe N, Ashenberg O, Farhi SL, Schapiro D, Divakar P, Miller E, Zollinger DR, Eng G, Schenkel JM, Su J, Shiau C, Yu P, Freed-Pastor WA, Abbondanza D, Mehta A, Gould J, Lambden C, Porter CBM, Tsankov A, Dionne D, Waldman J, Cuoco MS, Nguyen L, Delorey T, Phillips D, Barth JL, Kem M, Rodrigues C, Ciprani D, Roldan J, Zelga P, Jorgji V, Chen JH, Ely Z, Zhao D, Fuhrman K, Fropf R, Beechem JM, Loeffler JS, Ryan DP, Weekes CD, Ferrone CR, Qadan M, Aryee MJ, Jain RK, Neuberg DS, Wo JY, Hong TS, Xavier R, Aguirre AJ, Rozenblatt-Rosen O, Mino-Kenudson M, Castillo CF, Liss AS, Ting DT, Jacks T, Regev A. Hwang WL, et al. Among authors: guo ja. Nat Genet. 2022 Aug;54(8):1178-1191. doi: 10.1038/s41588-022-01134-8. Epub 2022 Jul 28. Nat Genet. 2022. PMID: 35902743
DNA repair and immune checkpoint blockade response.
Guo JA, Alshalalfa M, Kim DY, Hoffman HI, Shiau C, Su J, Hwang WL, Mahal BA. Guo JA, et al. Cancer Genet. 2022 Jun;264-265:1-4. doi: 10.1016/j.cancergen.2022.02.007. Epub 2022 Feb 24. Cancer Genet. 2022. PMID: 35245846
Racial Differences in Genomic Profiles of Breast Cancer.
Goel N, Kim DY, Guo JA, Zhao D, Mahal BA, Alshalalfa M. Goel N, et al. Among authors: guo ja. JAMA Netw Open. 2022 Mar 1;5(3):e220573. doi: 10.1001/jamanetworkopen.2022.0573. JAMA Netw Open. 2022. PMID: 35230441 Free PMC article.
28 results