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Page 1
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells.
Wing PAC, Keeley TP, Zhuang X, Lee JY, Prange-Barczynska M, Tsukuda S, Morgan SB, Harding AC, Argles ILA, Kurlekar S, Noerenberg M, Thompson CP, Huang KA, Balfe P, Watashi K, Castello A, Hinks TSC, James W, Ratcliffe PJ, Davis I, Hodson EJ, Bishop T, McKeating JA. Wing PAC, et al. Among authors: harding ac. Cell Rep. 2021 Apr 20;35(3):109020. doi: 10.1016/j.celrep.2021.109020. Epub 2021 Apr 5. Cell Rep. 2021. PMID: 33852916 Free PMC article.
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H; Medawar Laboratory Team; Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A; OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group; Tan TK, Schimanski L, Huang KA, Rijal P; PITCH (Protective Immunity T cells in Health Care Worker) Study Group; C-MORE/PHOSP-C Group; Frater J, Goulder P, Conlon CP, Jeffery K, Dold C, Pollard AJ, Sigal A, de Oliveira T, Townsend AR, Klenerman P, Dunachie SJ, Barnes E, Carroll MW, James WS. Skelly DT, et al. Among authors: harding ac. Nat Commun. 2021 Aug 17;12(1):5061. doi: 10.1038/s41467-021-25167-5. Nat Commun. 2021. PMID: 34404775 Free PMC article.
Divergent trajectories of antiviral memory after SARS-CoV-2 infection.
Tomic A, Skelly DT, Ogbe A, O'Connor D, Pace M, Adland E, Alexander F, Ali M, Allott K, Azim Ansari M, Belij-Rammerstorfer S, Bibi S, Blackwell L, Brown A, Brown H, Cavell B, Clutterbuck EA, de Silva T, Eyre D, Lumley S, Flaxman A, Grist J, Hackstein CP, Halkerston R, Harding AC, Hill J, James T, Jay C, Johnson SA, Kronsteiner B, Lie Y, Linder A, Longet S, Marinou S, Matthews PC, Mellors J, Petropoulos C, Rongkard P, Sedik C, Silva-Reyes L, Smith H, Stockdale L, Taylor S, Thomas S, Tipoe T, Turtle L, Vieira VA, Wrin T; OPTIC Clinical Group; PITCH Study Group; C-MORE Group; Pollard AJ, Lambe T, Conlon CP, Jeffery K, Travis S, Goulder P, Frater J, Mentzer AJ, Stafford L, Carroll MW, James WS, Klenerman P, Barnes E, Dold C, Dunachie SJ. Tomic A, et al. Among authors: harding ac. Nat Commun. 2022 Mar 10;13(1):1251. doi: 10.1038/s41467-022-28898-1. Nat Commun. 2022. PMID: 35273178 Free PMC article.
T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study.
Angyal A, Longet S, Moore SC, Payne RP, Harding A, Tipton T, Rongkard P, Ali M, Hering LM, Meardon N, Austin J, Brown R, Skelly D, Gillson N, Dobson SL, Cross A, Sandhar G, Kilby JA, Tyerman JK, Nicols AR, Spegarova JS, Mehta H, Hornsby H, Whitham R, Conlon CP, Jeffery K, Goulder P, Frater J, Dold C, Pace M, Ogbe A, Brown H, Ansari MA, Adland E, Brown A, Chand M, Shields A, Matthews PC, Hopkins S, Hall V, James W, Rowland-Jones SL, Klenerman P, Dunachie S, Richter A, Duncan CJA, Barnes E, Carroll M, Turtle L, de Silva TI; PITCH Consortium. Angyal A, et al. Lancet Microbe. 2022 Jan;3(1):e21-e31. doi: 10.1016/S2666-5247(21)00275-5. Epub 2021 Nov 9. Lancet Microbe. 2022. PMID: 34778853 Free PMC article.
A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern.
Ertesvåg NU, Xiao J, Zhou F, Ljostveit S, Sandnes H, Lartey S, Sævik M, Hansen L, Madsen A, Mohn KGI, Fjelltveit E, Olofsson JS, Tan TK, Rijal P, Schimanski L, Øyen S, Brokstad KA, Dunachie S, Jämsén A, James WS, Harding AC, Harvala H, Nguyen D, Roberts D; PHE Virology group; Zambon M; Oxford collaborative group; Townsend A; Bergen COVID-19 Research Group; Langeland N, Cox RJ. Ertesvåg NU, et al. Among authors: harding ac. Commun Med (Lond). 2022 Apr 5;2:36. doi: 10.1038/s43856-022-00091-x. eCollection 2022. Commun Med (Lond). 2022. PMID: 35603265 Free PMC article.
Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection.
Hou MM, Harding AC, Barber NM, Kundu P, Bach FA, Salkeld J, Themistocleous Y, Greenwood NM, Cho JS, Barrett JR, Nugent FL, Rawlinson TA, Hodgson SH, Khozoee B, Mac Lochlainn DJ, Cowan RE, Poulton ID, Baker M, Kingham L, Mitton CH, Platt A, Lopez Ramon R, Ramos Lopez F, Thomas M, Skinner K, Quinkert D, Pipini D, Lias AM, Bardelli M, Edwards NJ, Donnellan FR, Biswas S, Rayner JC, Nielsen CM, Silk SE, Draper SJ, Nahrendorf W, Spence PJ, Minassian AM. Hou MM, et al. Among authors: harding ac. Nat Commun. 2025 Sep 25;16(1):8385. doi: 10.1038/s41467-025-63104-y. Nat Commun. 2025. PMID: 40998768 Free PMC article. Clinical Trial.
Plasmodium falciparum infection induces T cell tolerance that is associated with decreased disease severity upon re-infection.
Muñoz Sandoval D, Bach FA, Ivens A, Harding AC, Smith NL, Mazurczyk M, Themistocleous Y, Edwards NJ, Silk SE, Barrett JR, Cowan GJM, Napolitani G, Savill NJ, Draper SJ, Minassian AM, Nahrendorf W, Spence PJ. Muñoz Sandoval D, et al. Among authors: harding ac. J Exp Med. 2025 Jul 7;222(7):e20241667. doi: 10.1084/jem.20241667. Epub 2025 Apr 11. J Exp Med. 2025. PMID: 40214640 Free PMC article.
A systematic analysis of the human immune response to Plasmodium vivax.
Bach FA, Muñoz Sandoval D, Mazurczyk M, Themistocleous Y, Rawlinson TA, Harding AC, Kemp A, Silk SE, Barrett JR, Edwards NJ, Ivens A, Rayner JC, Minassian AM, Napolitani G, Draper SJ, Spence PJ. Bach FA, et al. Among authors: harding ac. J Clin Invest. 2023 Oct 16;133(20):e152463. doi: 10.1172/JCI152463. J Clin Invest. 2023. PMID: 37616070 Free PMC article.
12 results