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The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.
Hauenschild R, Tserovski L, Schmid K, Thüring K, Winz ML, Sharma S, Entian KD, Wacheul L, Lafontaine DL, Anderson J, Alfonzo J, Hildebrandt A, Jäschke A, Motorin Y, Helm M. Hauenschild R, et al. Among authors: hildebrandt a. Nucleic Acids Res. 2015 Nov 16;43(20):9950-64. doi: 10.1093/nar/gkv895. Epub 2015 Sep 13. Nucleic Acids Res. 2015. PMID: 26365242 Free PMC article.
Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes.
Werner S, Schmidt L, Marchand V, Kemmer T, Falschlunger C, Sednev MV, Bec G, Ennifar E, Höbartner C, Micura R, Motorin Y, Hildebrandt A, Helm M. Werner S, et al. Among authors: hildebrandt a. Nucleic Acids Res. 2020 Apr 17;48(7):3734-3746. doi: 10.1093/nar/gkaa113. Nucleic Acids Res. 2020. PMID: 32095818 Free PMC article.
CARE: context-aware sequencing read error correction.
Kallenborn F, Hildebrandt A, Schmidt B. Kallenborn F, et al. Among authors: hildebrandt a. Bioinformatics. 2021 May 17;37(7):889-895. doi: 10.1093/bioinformatics/btaa738. Bioinformatics. 2021. PMID: 32818262
The RMaP challenge of predicting RNA modifications by nanopore sequencing.
Spangenberg J, Mündnich S, Busch A, Pastore S, Wierczeiko A, Goettsch W, Dietrich V, Pryszcz LP, Cruciani S, Novoa EM, Joshi K, Perera R, Di Giorgio S, Arrubarrena P, Tellioglu I, Poon CL, Wan YK, Göke J, Hildebrandt A, Dieterich C, Helm M, Marz M, Gerber S, Alagna N. Spangenberg J, et al. Among authors: hildebrandt a. Commun Chem. 2025 Apr 12;8(1):115. doi: 10.1038/s42004-025-01507-0. Commun Chem. 2025. PMID: 40221591 Free PMC article.
CellLineNavigator: a workbench for cancer cell line analysis.
Krupp M, Itzel T, Maass T, Hildebrandt A, Galle PR, Teufel A. Krupp M, et al. Among authors: hildebrandt a. Nucleic Acids Res. 2013 Jan;41(Database issue):D942-8. doi: 10.1093/nar/gks1012. Epub 2012 Oct 31. Nucleic Acids Res. 2013. PMID: 23118487 Free PMC article.
468 results