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Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues.
Castillo-Armengol J, Barquissau V, Geller S, Ji H, Severi I, Venema W, Fenandez EA, Moret C, Huber K, Leal-Esteban LC, Nasrallah A, Martinez-Carreres L, Niederhäuser G, Seoane-Collazo P, Lagarrigue S, López M, Giordano A, Croizier S, Thorens B, Lopez-Mejia IC, Fajas L. Castillo-Armengol J, et al. EMBO Rep. 2020 Sep 3;21(9):e49807. doi: 10.15252/embr.201949807. Epub 2020 Jul 12. EMBO Rep. 2020. PMID: 32657019 Free PMC article.
CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer.
Ziegler DV, Parashar K, Leal-Esteban L, López-Alcalá J, Castro W, Zanou N, Martinez-Carreres L, Huber K, Berney XP, Malagón MM, Roger C, Berger MA, Gouriou Y, Paone G, Gallart-Ayala H, Sflomos G, Ronchi C, Ivanisevic J, Brisken C, Rieusset J, Irving M, Fajas L. Ziegler DV, et al. Nat Commun. 2025 Jan 9;16(1):541. doi: 10.1038/s41467-024-55605-z. Nat Commun. 2025. PMID: 39788939 Free PMC article.
Precision Oncology in Northern Germany - Integrating Multi-Omics and AI to Support Evidence-Based Molecular Tumor Boards.
Vorwerk J, Leypoldt L, Schwandt J, Kohler J, Nimmagadda SC, Ahmed H, Patnana PK, Hönemann H, Helbing T, Feierabend S, Dazert E, Oelschläger L, Beder T, Bastian L, Sommer F, Zech H, Kriegs M, Dauth A, Ailani D, Albers-Leischner C, Christopeit M, Heckl S, Busch H, Habig S, Ückert F, Fliedner SMJ, Gebauer N, von Bubnoff N, Khandanpour C, Huber K. Vorwerk J, et al. Among authors: huber k. Oncol Res Treat. 2026 Jul 16:1-23. doi: 10.1159/000553462. Online ahead of print. Oncol Res Treat. 2026. PMID: 42461906 Review.
Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.
Lu J, Rao SR, Knowles H, Zhan H, Gamez B, Qin M, Platt E, Frost LR, Allen TJ, Marshall G, Huber KVM, Bauer LG, Vendrell I, O'Brien DP, Kessler B, Horne A, Reid IR, Bountra C, Kirkland JL, Khosla S, Ebetino FH, Roldan E, Russell RGG, Edwards JR. Lu J, et al. Among authors: huber kvm. Signal Transduct Target Ther. 2026 Jul 15;11(1):277. doi: 10.1038/s41392-026-02799-x. Signal Transduct Target Ther. 2026. PMID: 42448670 Free PMC article.
2,218 results