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Endothelial to mesenchymal transition in kidney fibrosis.
Jacobs ME, de Vries DK, Engelse MA, Dumas SJ, Rabelink TJ. Jacobs ME, et al. Nephrol Dial Transplant. 2024 Apr 26;39(5):752-760. doi: 10.1093/ndt/gfad238. Nephrol Dial Transplant. 2024. PMID: 37968135 Review.
A cell-free nutrient-supplemented perfusate allows four-day ex vivo metabolic preservation of human kidneys.
de Haan MJA, Jacobs ME, Witjas FMR, de Graaf AMA, Sánchez-López E, Kostidis S, Giera M, Calderon Novoa F, Chu T, Selzner M, Maanaoui M, de Vries DK, Kers J, Alwayn IPJ, van Kooten C, Heijs B, Wang G, Engelse MA, Rabelink TJ. de Haan MJA, et al. Among authors: jacobs me. Nat Commun. 2024 May 13;15(1):3818. doi: 10.1038/s41467-024-47106-w. Nat Commun. 2024. PMID: 38740760 Free PMC article.
Preclinical lentiviral hematopoietic stem cell gene therapy corrects Pompe disease-related muscle and neurological manifestations.
Yoon JK, Schindler JW, Loperfido M, Baricordi C, DeAndrade MP, Jacobs ME, Treleaven C, Plasschaert RN, Yan A, Barese CN, Dogan Y, Chen VP, Fiorini C, Hull F, Barbarossa L, Unnisa Z, Ivanov D, Kutner RH, Guda S, Oborski C, Maiwald T, Michaud V, Rothe M, Schambach A, Pfeifer R, Mason C, Biasco L, van Til NP. Yoon JK, et al. Among authors: jacobs me. Mol Ther. 2024 Sep 17:S1525-0016(24)00606-3. doi: 10.1016/j.ymthe.2024.09.024. Online ahead of print. Mol Ther. 2024. PMID: 39295144
Screening chimeric GAA variants in preclinical study results in hematopoietic stem cell gene therapy candidate vectors for Pompe disease.
Dogan Y, Barese CN, Schindler JW, Yoon JK, Unnisa Z, Guda S, Jacobs ME, Oborski C, Maiwald T, Clarke DL, Schambach A, Pfeifer R, Harper C, Mason C, van Til NP. Dogan Y, et al. Among authors: jacobs me. Mol Ther Methods Clin Dev. 2022 Nov 3;27:464-487. doi: 10.1016/j.omtm.2022.10.017. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36419467 Free PMC article.
56 results