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9 results
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Charting cellular identity during human in vitro β-cell differentiation.
Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA. Veres A, et al. Among authors: Kenty JH. Nature. 2019 May;569(7756):368-373. doi: 10.1038/s41586-019-1168-5. Epub 2019 May 8. Nature. 2019. PMID: 31068696 Free PMC article.
YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells.
Rosado-Olivieri EA, Anderson K, Kenty JH, Melton DA. Rosado-Olivieri EA, et al. Among authors: Kenty JH. Nat Commun. 2019 Apr 1;10(1):1464. doi: 10.1038/s41467-019-09404-6. Nat Commun. 2019. PMID: 30931946 Free PMC article.
Generation of hypoimmunogenic human pluripotent stem cells.
Han X, Wang M, Duan S, Franco PJ, Kenty JH, Hedrick P, Xia Y, Allen A, Ferreira LMR, Strominger JL, Melton DA, Meissner TB, Cowan CA. Han X, et al. Among authors: Kenty JH. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10441-10446. doi: 10.1073/pnas.1902566116. Epub 2019 Apr 30. Proc Natl Acad Sci U S A. 2019. PMID: 31040209 Free PMC article.
Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human β Cells.
Rosado-Olivieri EA, Aigha II, Kenty JH, Melton DA. Rosado-Olivieri EA, et al. Among authors: Kenty JH. Cell Metab. 2020 Feb 4;31(2):327-338.e6. doi: 10.1016/j.cmet.2019.12.009. Epub 2020 Jan 9. Cell Metab. 2020. PMID: 31928884
Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis.
Davis JC, Alves TC, Helman A, Chen JC, Kenty JH, Cardone RL, Liu DR, Kibbey RG, Melton DA. Davis JC, et al. Among authors: Kenty JH. Cell Rep. 2020 May 12;31(6):107623. doi: 10.1016/j.celrep.2020.107623. Cell Rep. 2020. PMID: 32402282 Free article.
A method for the generation of human stem cell-derived alpha cells.
Peterson QP, Veres A, Chen L, Slama MQ, Kenty JHR, Hassoun S, Brown MR, Dou H, Duffy CD, Zhou Q, Matveyenko AV, Tyrberg B, Sörhede-Winzell M, Rorsman P, Melton DA. Peterson QP, et al. Among authors: Kenty JHR. Nat Commun. 2020 May 7;11(1):2241. doi: 10.1038/s41467-020-16049-3. Nat Commun. 2020. PMID: 32382023 Free PMC article.
Circadian Entrainment Triggers Maturation of Human In Vitro Islets.
Alvarez-Dominguez JR, Donaghey J, Rasouli N, Kenty JHR, Helman A, Charlton J, Straubhaar JR, Meissner A, Melton DA. Alvarez-Dominguez JR, et al. Among authors: Kenty JHR. Cell Stem Cell. 2020 Jan 2;26(1):108-122.e10. doi: 10.1016/j.stem.2019.11.011. Epub 2019 Dec 12. Cell Stem Cell. 2020. PMID: 31839570
Synchronized stimulation and continuous insulin sensing in a microfluidic human Islet on a Chip designed for scalable manufacturing.
Glieberman AL, Pope BD, Zimmerman JF, Liu Q, Ferrier JP, Kenty JHR, Schrell AM, Mukhitov N, Shores KL, Tepole AB, Melton DA, Roper MG, Parker KK. Glieberman AL, et al. Among authors: Kenty JHR. Lab Chip. 2019 Sep 10;19(18):2993-3010. doi: 10.1039/c9lc00253g. Lab Chip. 2019. PMID: 31464325
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