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Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.
Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE. Ferdaoussi M, et al. Among authors: kibbey rg. J Clin Invest. 2015 Oct 1;125(10):3847-60. doi: 10.1172/JCI82498. Epub 2015 Sep 21. J Clin Invest. 2015. PMID: 26389676 Free PMC article.
Glutamate is a positive autocrine signal for glucagon release.
Cabrera O, Jacques-Silva MC, Speier S, Yang SN, Köhler M, Fachado A, Vieira E, Zierath JR, Kibbey R, Berman DM, Kenyon NS, Ricordi C, Caicedo A, Berggren PO. Cabrera O, et al. Cell Metab. 2008 Jun;7(6):545-54. doi: 10.1016/j.cmet.2008.03.004. Cell Metab. 2008. PMID: 18522835 Free PMC article.
Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis.
Ouyang X, Han SN, Zhang JY, Dioletis E, Nemeth BT, Pacher P, Feng D, Bataller R, Cabezas J, Stärkel P, Caballeria J, LePine Pongratz R, Cai SY, Schnabl B, Hoque R, Chen Y, Yang WH, Garcia-Martinez I, Wang FS, Gao B, Torok NJ, Kibbey RG, Mehal WZ. Ouyang X, et al. Among authors: kibbey rg. Cell Metab. 2018 May 1;27(5):1156. doi: 10.1016/j.cmet.2018.04.007. Cell Metab. 2018. PMID: 29719229 No abstract available.
Effect of aging on muscle mitochondrial substrate utilization in humans.
Petersen KF, Morino K, Alves TC, Kibbey RG, Dufour S, Sono S, Yoo PS, Cline GW, Shulman GI. Petersen KF, et al. Among authors: kibbey rg. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11330-4. doi: 10.1073/pnas.1514844112. Epub 2015 Aug 24. Proc Natl Acad Sci U S A. 2015. PMID: 26305973 Free PMC article.
Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.
Alves TC, Pongratz RL, Zhao X, Yarborough O, Sereda S, Shirihai O, Cline GW, Mason G, Kibbey RG. Alves TC, et al. Among authors: kibbey rg. Cell Metab. 2015 Nov 3;22(5):936-47. doi: 10.1016/j.cmet.2015.08.021. Epub 2015 Sep 24. Cell Metab. 2015. PMID: 26411341 Free PMC article.
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