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Monomeric site-specific nucleases for genome editing.
Kleinstiver BP, Wolfs JM, Kolaczyk T, Roberts AK, Hu SX, Edgell DR. Kleinstiver BP, et al. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8061-6. doi: 10.1073/pnas.1117984109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566637 Free PMC article.
Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.
Black JC, Atabakhsh E, Kim J, Biette KM, Van Rechem C, Ladd B, Burrowes PD, Donado C, Mattoo H, Kleinstiver BP, Song B, Andriani G, Joung JK, Iliopoulos O, Montagna C, Pillai S, Getz G, Whetstine JR. Black JC, et al. Among authors: kleinstiver bp. Genes Dev. 2015 May 15;29(10):1018-31. doi: 10.1101/gad.259796.115. Genes Dev. 2015. PMID: 25995187 Free PMC article.
Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Kleinstiver BP, Prew MS, Tsai SQ, Topkar VV, Nguyen NT, Zheng Z, Gonzales AP, Li Z, Peterson RT, Yeh JR, Aryee MJ, Joung JK. Kleinstiver BP, et al. Nature. 2015 Jul 23;523(7561):481-5. doi: 10.1038/nature14592. Epub 2015 Jun 22. Nature. 2015. PMID: 26098369 Free PMC article.
53 results