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Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.
Rugel A, Tarpley RS, Lopez A, Menard T, Guzman MA, Taylor AB, Cao X, Kovalskyy D, Chevalier FD, Anderson TJC, Hart PJ, LoVerde PT, McHardy SF. Rugel A, et al. Among authors: kovalskyy d. ACS Med Chem Lett. 2018 Sep 14;9(10):967-973. doi: 10.1021/acsmedchemlett.8b00257. eCollection 2018 Oct 11. ACS Med Chem Lett. 2018. PMID: 30344901 Free PMC article.
An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.
Guzman MA, Rugel AR, Tarpley RS, Alwan SN, Chevalier FD, Kovalskyy DP, Cao X, Holloway SP, Anderson TJC, Taylor AB, McHardy SF, LoVerde PT. Guzman MA, et al. Among authors: kovalskyy dp. PLoS Negl Trop Dis. 2020 Aug 18;14(8):e0008517. doi: 10.1371/journal.pntd.0008517. eCollection 2020 Aug. PLoS Negl Trop Dis. 2020. PMID: 32810153 Free PMC article.
Inhibition of heat-induced protein aggregation by zirconium phthalocyanines.
Chernii S, Losytskyy M, Tretyakova I, Kharchuk M, Vakarov S, Kovalskyy D, Gerasymchyk Y, Pekhnyo V, Chernii V, Kovalska V. Chernii S, et al. Among authors: kovalskyy d. Proteins. 2023 Jul;91(7):890-903. doi: 10.1002/prot.26475. Epub 2023 Feb 13. Proteins. 2023. PMID: 36732896
Targeting Tat-TAR RNA Interaction for HIV-1 Inhibition.
Alanazi A, Ivanov A, Kumari N, Lin X, Wang S, Kovalskyy D, Nekhai S. Alanazi A, et al. Among authors: kovalskyy d. Viruses. 2021 Oct 6;13(10):2004. doi: 10.3390/v13102004. Viruses. 2021. PMID: 34696435 Free PMC article.
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem N, Roske Y, Kovalskyy D, Platonov MO, Balinskyi O, Kreuchwig A, Saupe J, Fang L, Diehl A, Schmieder P, Krause G, Rademann J, Heinemann U, Birchmeier W, Oschkinat H. Kamdem N, et al. Among authors: kovalskyy d. Magn Reson (Gott). 2021 Jun 2;2(1):355-374. doi: 10.5194/mr-2-355-2021. eCollection 2021. Magn Reson (Gott). 2021. PMID: 37904770 Free PMC article.
Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo.
Leblanc R, Kashyap R, Barral K, Egea-Jimenez AL, Kovalskyy D, Feracci M, Garcia M, Derviaux C, Betzi S, Ghossoub R, Platonov M, Roche P, Morelli X, Hoffer L, Zimmermann P. Leblanc R, et al. Among authors: kovalskyy d. J Extracell Vesicles. 2020 Dec;10(2):e12039. doi: 10.1002/jev2.12039. Epub 2020 Dec 15. J Extracell Vesicles. 2020. PMID: 33343836 Free PMC article.
Novel mTORC1 Inhibitors Kill Glioblastoma Stem Cells.
Sandoval JA, Tomilov A, Datta S, Allen S, O'Donnell R, Sears T, Woolard K, Kovalskyy D, Angelastro JM, Cortopassi G. Sandoval JA, et al. Among authors: kovalskyy d. Pharmaceuticals (Basel). 2020 Nov 24;13(12):419. doi: 10.3390/ph13120419. Pharmaceuticals (Basel). 2020. PMID: 33255358 Free PMC article.
Structural basis of RNA cap modification by SARS-CoV-2.
Viswanathan T, Arya S, Chan SH, Qi S, Dai N, Misra A, Park JG, Oladunni F, Kovalskyy D, Hromas RA, Martinez-Sobrido L, Gupta YK. Viswanathan T, et al. Among authors: kovalskyy d. Nat Commun. 2020 Jul 24;11(1):3718. doi: 10.1038/s41467-020-17496-8. Nat Commun. 2020. PMID: 32709886 Free PMC article.
28 results