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Page 1
CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer.
Ziegler DV, Parashar K, Leal-Esteban L, López-Alcalá J, Castro W, Zanou N, Martinez-Carreres L, Huber K, Berney XP, Malagón MM, Roger C, Berger MA, Gouriou Y, Paone G, Gallart-Ayala H, Sflomos G, Ronchi C, Ivanisevic J, Brisken C, Rieusset J, Irving M, Fajas L. Ziegler DV, et al. Among authors: leal esteban l. Nat Commun. 2025 Jan 9;16(1):541. doi: 10.1038/s41467-024-55605-z. Nat Commun. 2025. PMID: 39788939 Free PMC article.
Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues.
Castillo-Armengol J, Barquissau V, Geller S, Ji H, Severi I, Venema W, Fenandez EA, Moret C, Huber K, Leal-Esteban LC, Nasrallah A, Martinez-Carreres L, Niederhäuser G, Seoane-Collazo P, Lagarrigue S, López M, Giordano A, Croizier S, Thorens B, Lopez-Mejia IC, Fajas L. Castillo-Armengol J, et al. Among authors: leal esteban lc. EMBO Rep. 2020 Sep 3;21(9):e49807. doi: 10.15252/embr.201949807. Epub 2020 Jul 12. EMBO Rep. 2020. PMID: 32657019 Free PMC article.
Cell cycle regulators in cancer cell metabolism.
Leal-Esteban LC, Fajas L. Leal-Esteban LC, et al. Biochim Biophys Acta Mol Basis Dis. 2020 May 1;1866(5):165715. doi: 10.1016/j.bbadis.2020.165715. Epub 2020 Feb 5. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32035102 Free article. Review.
CDK4 Regulates Lysosomal Function and mTORC1 Activation to Promote Cancer Cell Survival.
Martínez-Carreres L, Puyal J, Leal-Esteban LC, Orpinell M, Castillo-Armengol J, Giralt A, Dergai O, Moret C, Barquissau V, Nasrallah A, Pabois A, Zhang L, Romero P, Lopez-Mejia IC, Fajas L. Martínez-Carreres L, et al. Among authors: leal esteban lc. Cancer Res. 2019 Oct 15;79(20):5245-5259. doi: 10.1158/0008-5472.CAN-19-0708. Epub 2019 Aug 8. Cancer Res. 2019. PMID: 31395606 Free PMC article.
Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA.
Rothé B, Leal-Esteban L, Bernet F, Urfer S, Doerr N, Weimbs T, Iwaszkiewicz J, Constam DB. Rothé B, et al. Among authors: leal esteban l. Mol Cell Biol. 2015 Oct;35(19):3339-53. doi: 10.1128/MCB.00341-15. Epub 2015 Jul 27. Mol Cell Biol. 2015. PMID: 26217012 Free PMC article.
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