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Characterization of a catalytically efficient acidic RNA-cleaving deoxyribozyme.
Kandadai SA, Li Y. Kandadai SA, et al. Among authors: li y. Nucleic Acids Res. 2006 Jan 3;33(22):7164-75. doi: 10.1093/nar/gki1013. Print 2005. Nucleic Acids Res. 2006. PMID: 16391005 Free PMC article.
We previously demonstrated--through the isolation of RNA-cleaving deoxyribozymes by in vitro selection that are catalytically active in highly acidic solutions--that DNA, despite its chemical simplicity, could perform catalysis under challenging chemical conditions [Liu,Z., Mei,S …
We previously demonstrated--through the isolation of RNA-cleaving deoxyribozymes by in vitro selection that are catalytically active in high …
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