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Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues.
Castillo-Armengol J, Barquissau V, Geller S, Ji H, Severi I, Venema W, Fenandez EA, Moret C, Huber K, Leal-Esteban LC, Nasrallah A, Martinez-Carreres L, Niederhäuser G, Seoane-Collazo P, Lagarrigue S, López M, Giordano A, Croizier S, Thorens B, Lopez-Mejia IC, Fajas L. Castillo-Armengol J, et al. EMBO Rep. 2020 Sep 3;21(9):e49807. doi: 10.15252/embr.201949807. Epub 2020 Jul 12. EMBO Rep. 2020. PMID: 32657019 Free PMC article.
Antagonistic functions of LMNA isoforms in energy expenditure and lifespan.
Lopez-Mejia IC, de Toledo M, Chavey C, Lapasset L, Cavelier P, Lopez-Herrera C, Chebli K, Fort P, Beranger G, Fajas L, Amri EZ, Casas F, Tazi J. Lopez-Mejia IC, et al. EMBO Rep. 2014 May;15(5):529-39. doi: 10.1002/embr.201338126. Epub 2014 Mar 17. EMBO Rep. 2014. PMID: 24639560 Free PMC article.
Cell cycle regulation of mitochondrial function.
Lopez-Mejia IC, Fajas L. Lopez-Mejia IC, et al. Curr Opin Cell Biol. 2015 Apr;33:19-25. doi: 10.1016/j.ceb.2014.10.006. Epub 2014 Nov 12. Curr Opin Cell Biol. 2015. PMID: 25463842 Review.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14. J Clin Invest. 2016. Retraction in: J Clin Invest. 2023 Mar 15;133(6):e170315. doi: 10.1172/JCI170315. PMID: 26657864 Free PMC article. Retracted.
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Mol Cell. 2017 Oct 19;68(2):336-349.e6. doi: 10.1016/j.molcel.2017.09.034. Mol Cell. 2017. PMID: 29053957 Free article.
Cdkn2a deficiency promotes adipose tissue browning.
Rabhi N, Hannou SA, Gromada X, Salas E, Yao X, Oger F, Carney C, Lopez-Mejia IC, Durand E, Rabearivelo I, Bonnefond A, Caron E, Fajas L, Dani C, Froguel P, Annicotte JS. Rabhi N, et al. Mol Metab. 2018 Feb;8:65-76. doi: 10.1016/j.molmet.2017.11.012. Epub 2017 Dec 1. Mol Metab. 2018. PMID: 29237539 Free PMC article.
39 results