Mehellou Y - Search Results

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35 results

Results are displayed in a computed author sort order. Results by year timeline is unavailable

Page 1

Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses.

Kadri H, Taher TE, Xu Q, Sharif M, Ashby E, Bryan RT, Willcox BE, Mehellou Y. Kadri H, et al. Among authors: mehellou y. J Med Chem. 2020 Oct 8;63(19):11258-11270. doi: 10.1021/acs.jmedchem.0c01232. Epub 2020 Sep 29. J Med Chem. 2020. PMID: 32930595 Free PMC article.

Aryloxy Triester Phosphoramidates as Phosphoserine Prodrugs: A Proof of Concept Study.

Miccoli A, Dhiani BA, Thornton PJ, Lambourne OA, James E, Kadri H, Mehellou Y. Miccoli A, et al. Among authors: mehellou y. ChemMedChem. 2020 Apr 20;15(8):671-674. doi: 10.1002/cmdc.202000034. Epub 2020 Mar 26. ChemMedChem. 2020. PMID: 32162793

A two-pronged attack on antibiotic-resistant microbes.

Mehellou Y, Willcox BE. Mehellou Y, et al. Nature. 2021 Jan;589(7843):517-518. doi: 10.1038/d41586-020-03660-z. Nature. 2021. PMID: 33432214 No abstract available.

SPAK and OSR1 kinases bind and phosphorylate the β₂-Adrenergic receptor.

Elzwawi A, Grafton G, Barnes NM, Mehellou Y. Elzwawi A, et al. Among authors: mehellou y. Biochem Biophys Res Commun. 2020 Oct 29;532(1):88-93. doi: 10.1016/j.bbrc.2020.07.143. Epub 2020 Aug 20. Biochem Biophys Res Commun. 2020. PMID: 32828531

The Cul4-DDB1-WDR3/WDR6 Complex Binds SPAK and OSR1 Kinases in a Phosphorylation-Dependent Manner.

Dhiani BA, Mehellou Y. Dhiani BA, et al. Among authors: mehellou y. Chembiochem. 2020 Mar 2;21(5):638-643. doi: 10.1002/cbic.201900454. Epub 2019 Oct 15. Chembiochem. 2020. PMID: 31614064

Sequence specific assignment and determination of OSR1 C-terminal domain structure by NMR.

AlAmri MA, Jeeves M, Mehellou Y. AlAmri MA, et al. Among authors: mehellou y. Biochem Biophys Res Commun. 2019 Apr 30;512(2):338-343. doi: 10.1016/j.bbrc.2019.03.065. Epub 2019 Mar 17. Biochem Biophys Res Commun. 2019. PMID: 30894278

Phosphotyrosine prodrugs: design, synthesis and anti-STAT3 activity of ISS-610 aryloxy triester phosphoramidate prodrugs.

Miccoli A, Dhiani BA, Mehellou Y. Miccoli A, et al. Among authors: mehellou y. Medchemcomm. 2018 Nov 7;10(2):200-208. doi: 10.1039/c8md00244d. eCollection 2019 Feb 1. Medchemcomm. 2018. PMID: 30881608 Free PMC article.

The ProTide Prodrug Technology: Where Next?

Alanazi AS, James E, Mehellou Y. Alanazi AS, et al. Among authors: mehellou y. ACS Med Chem Lett. 2018 Dec 20;10(1):2-5. doi: 10.1021/acsmedchemlett.8b00586. eCollection 2019 Jan 10. ACS Med Chem Lett. 2018. PMID: 30655934 Free PMC article.

Chemical Strategies for Activating PINK1, a Protein Kinase Mutated in Parkinson's Disease.

Lambourne OA, Mehellou Y. Lambourne OA, et al. Among authors: mehellou y. Chembiochem. 2018 Dec 4;19(23):2433-2437. doi: 10.1002/cbic.201800497. Epub 2018 Nov 7. Chembiochem. 2018. PMID: 30248222

C-terminal phosphorylation of SPAK and OSR1 kinases promotes their binding and activation by the scaffolding protein MO25.

Mehellou Y, Alamri MA, Dhiani BA, Kadri H. Mehellou Y, et al. Biochem Biophys Res Commun. 2018 Sep 10;503(3):1868-1873. doi: 10.1016/j.bbrc.2018.07.128. Epub 2018 Jul 27. Biochem Biophys Res Commun. 2018. PMID: 30060950

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