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Nucleoside Phosphate and Phosphonate Prodrug Clinical Candidates.
Thornton PJ, Kadri H, Miccoli A, Mehellou Y. Thornton PJ, et al. Among authors: mehellou y. J Med Chem. 2016 Dec 8;59(23):10400-10410. doi: 10.1021/acs.jmedchem.6b00523. Epub 2016 Sep 8. J Med Chem. 2016. PMID: 27559756 Review.
Kinetin Riboside and Its ProTides Activate the Parkinson's Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization.
Osgerby L, Lai YC, Thornton PJ, Amalfitano J, Le Duff CS, Jabeen I, Kadri H, Miccoli A, Tucker JHR, Muqit MMK, Mehellou Y. Osgerby L, et al. Among authors: mehellou y. J Med Chem. 2017 Apr 27;60(8):3518-3524. doi: 10.1021/acs.jmedchem.6b01897. Epub 2017 Mar 28. J Med Chem. 2017. PMID: 28323427 Free PMC article.
BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain.
Salim M, Knowles TJ, Baker AT, Davey MS, Jeeves M, Sridhar P, Wilkie J, Willcox CR, Kadri H, Taher TE, Vantourout P, Hayday A, Mehellou Y, Mohammed F, Willcox BE. Salim M, et al. Among authors: mehellou y. ACS Chem Biol. 2017 Oct 20;12(10):2631-2643. doi: 10.1021/acschembio.7b00694. Epub 2017 Sep 14. ACS Chem Biol. 2017. PMID: 28862425 Free PMC article.
WNK Signaling Inhibitors as Potential Antihypertensive Drugs.
AlAmri MA, Kadri H, Dhiani BA, Mahmood S, Elzwawi A, Mehellou Y. AlAmri MA, et al. Among authors: mehellou y. ChemMedChem. 2017 Oct 20;12(20):1677-1686. doi: 10.1002/cmdc.201700425. Epub 2017 Sep 26. ChemMedChem. 2017. PMID: 28881465 Review.
40 results