Mescher MF - Search Results

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145 results

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Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells.

Curtsinger JM, Schmidt CS, Mondino A, Lins DC, Kedl RM, Jenkins MK, Mescher MF. Curtsinger JM, et al. Among authors: mescher mf. J Immunol. 1999 Mar 15;162(6):3256-62. J Immunol. 1999. PMID: 10092777

The roles of IL-12 in providing a third signal for clonal expansion of naive CD8 T cells.

Valenzuela J, Schmidt C, Mescher M. Valenzuela J, et al. J Immunol. 2002 Dec 15;169(12):6842-9. doi: 10.4049/jimmunol.169.12.6842. J Immunol. 2002. PMID: 12471116

Peptide antigen priming of naive, but not memory, CD8 T cells requires a third signal that can be provided by IL-12.

Schmidt CS, Mescher MF. Schmidt CS, et al. Among authors: mescher mf. J Immunol. 2002 Jun 1;168(11):5521-9. doi: 10.4049/jimmunol.168.11.5521. J Immunol. 2002. PMID: 12023347

The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo.

Harmala LA, Ingulli EG, Curtsinger JM, Lucido MM, Schmidt CS, Weigel BJ, Blazar BR, Mescher MF, Pennell CA. Harmala LA, et al. Among authors: mescher mf. J Immunol. 2002 Nov 15;169(10):5622-9. doi: 10.4049/jimmunol.169.10.5622. J Immunol. 2002. PMID: 12421941

Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function.

Curtsinger JM, Lins DC, Mescher MF. Curtsinger JM, et al. Among authors: mescher mf. J Exp Med. 2003 May 5;197(9):1141-51. doi: 10.1084/jem.20021910. J Exp Med. 2003. PMID: 12732656 Free PMC article.

CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine.

Curtsinger JM, Johnson CM, Mescher MF. Curtsinger JM, et al. Among authors: mescher mf. J Immunol. 2003 Nov 15;171(10):5165-71. doi: 10.4049/jimmunol.171.10.5165. J Immunol. 2003. PMID: 14607916

Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation.

Curtsinger JM, Valenzuela JO, Agarwal P, Lins D, Mescher MF. Curtsinger JM, et al. Among authors: mescher mf. J Immunol. 2005 Apr 15;174(8):4465-9. doi: 10.4049/jimmunol.174.8.4465. J Immunol. 2005. PMID: 15814665

CD4 T cell-dependent conditioning of dendritic cells to produce IL-12 results in CD8-mediated graft rejection and avoidance of tolerance.

Filatenkov AA, Jacovetty EL, Fischer UB, Curtsinger JM, Mescher MF, Ingulli E. Filatenkov AA, et al. Among authors: mescher mf. J Immunol. 2005 Jun 1;174(11):6909-17. doi: 10.4049/jimmunol.174.11.6909. J Immunol. 2005. PMID: 15905533

Signal 3 tolerant CD8 T cells degranulate in response to antigen but lack granzyme B to mediate cytolysis.

Curtsinger JM, Lins DC, Johnson CM, Mescher MF. Curtsinger JM, et al. Among authors: mescher mf. J Immunol. 2005 Oct 1;175(7):4392-9. doi: 10.4049/jimmunol.175.7.4392. J Immunol. 2005. PMID: 16177080

Molecular basis for checkpoints in the CD8 T cell response: tolerance versus activation.

Mescher MF, Agarwal P, Casey KA, Hammerbeck CD, Xiao Z, Curtsinger JM. Mescher MF, et al. Semin Immunol. 2007 Jun;19(3):153-61. doi: 10.1016/j.smim.2007.02.007. Epub 2007 Mar 26. Semin Immunol. 2007. PMID: 17382557 Free PMC article. Review.

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