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Circulating Human Metabolites Resulting from TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons from an Original Ex Vivo Clinical Trial.
Wauquier F, Boutin-Wittrant L, Krisa S, Valls J, Langhi C, Otero YF, Sirvent P, Peltier S, Bargetto M, Cazaubiel M, Sapone V, Bouchard-Mercier A, Roux V, Macian N, Pickering G, Wittrant Y. Wauquier F, et al. Among authors: otero yf. Nutrients. 2023 Apr 14;15(8):1903. doi: 10.3390/nu15081903. Nutrients. 2023. PMID: 37111121 Free PMC article.
Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption.
Langhi C, Vallier M, Otero YF, Maura M, Le Joubioux F, Groult H, Achour O, Pebriana RB, Giera M, Guigas B, Maugard T, Chassaing B, Peltier S, Bard JM, Sirvent P. Langhi C, et al. Among authors: otero yf. Nutrients. 2023 Dec 9;15(24):5056. doi: 10.3390/nu15245056. Nutrients. 2023. PMID: 38140315 Free PMC article.
A polyphenol-rich plant extract prevents hypercholesterolemia and modulates gut microbiota in western diet-fed mice.
Langhi C, Vallier M, Bron A, Otero YF, Maura M, Le Joubioux F, Blomberg N, Giera M, Guigas B, Maugard T, Chassaing B, Peltier S, Blanquet-Diot S, Bard JM, Sirvent P. Langhi C, et al. Among authors: otero yf. Front Cardiovasc Med. 2024 Jan 22;11:1342388. doi: 10.3389/fcvm.2024.1342388. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 38317864 Free PMC article.
TOTUM-63, a plant-based polyphenol-rich extract, improves glycaemic control in subjects with prediabetes or early stage newly-diagnosed type 2 diabetes in a randomized, double-blind, placebo-controlled trial.
Sirvent P, Chavanelle V, Otero YF, Bargetto M, Le Joubioux F, Boisseau N, Maugard T, Cazaubiel M, Pereira B, Guigas B, Hadjadj S, Peltier SL, Marette A, Bard JM. Sirvent P, et al. Among authors: otero yf. Diabetes Obes Metab. 2022 Dec;24(12):2331-2340. doi: 10.1111/dom.14817. Epub 2022 Aug 1. Diabetes Obes Metab. 2022. PMID: 35837981 Free PMC article. Clinical Trial.
Impact of TOTUM-63, a fibre and polyphenol rich plant-based composition, on gut and pancreatic hormone secretion in diet-induced obese mice.
Chavanelle V, Chanon S, Pinteur C, Loizon E, Vial G, Otero YF, Le Joubioux F, Maugard T, Peltier SL, Sirvent P, Morio B. Chavanelle V, et al. Among authors: otero yf. Nutr Metab Cardiovasc Dis. 2022 Jul;32(7):1797-1807. doi: 10.1016/j.numecd.2022.04.001. Epub 2022 Apr 22. Nutr Metab Cardiovasc Dis. 2022. PMID: 35618560
Editorial: New Insights Into Understanding and Managing NAFLD.
Escribano Ó, Francés DE, Otero YF, Egea J, González-Rodríguez Á. Escribano Ó, et al. Among authors: otero yf. Front Med (Lausanne). 2021 Nov 12;8:777740. doi: 10.3389/fmed.2021.777740. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34869497 Free PMC article. No abstract available.
The TOTUM-63 Supplement and High-Intensity Interval Training Combination Limits Weight Gain, Improves Glycemic Control, and Influences the Composition of Gut Mucosa-Associated Bacteria in Rats on a High Fat Diet.
Dupuit M, Chavanelle V, Chassaing B, Perriere F, Etienne M, Plissonneau C, Boscaro A, Barnich N, Pialoux V, Maugard T, Le Joubioux F, Peltier S, Sirvent P, Otero YF, Boisseau N. Dupuit M, et al. Among authors: otero yf. Nutrients. 2021 May 7;13(5):1569. doi: 10.3390/nu13051569. Nutrients. 2021. PMID: 34066988 Free PMC article.
29 results