Picard D - Search Results

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483 results

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Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life.

Bhattacharya K, Maiti S, Zahoran S, Weidenauer L, Hany D, Wider D, Bernasconi L, Quadroni M, Collart M, Picard D. Bhattacharya K, et al. Among authors: picard d. Nat Commun. 2022 Oct 21;13(1):6271. doi: 10.1038/s41467-022-33916-3. Nat Commun. 2022. PMID: 36270993 Free PMC article.

The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities.

Wider D, Péli-Gulli MP, Briand PA, Tatu U, Picard D. Wider D, et al. Among authors: picard d. Mol Biochem Parasitol. 2009 Apr;164(2):147-52. doi: 10.1016/j.molbiopara.2008.12.011. Mol Biochem Parasitol. 2009. PMID: 19320098 Free article.

Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapy.

Fierro-Monti I, Echeverria P, Racle J, Hernandez C, Picard D, Quadroni M. Fierro-Monti I, et al. Among authors: picard d. PLoS One. 2013 Nov 27;8(11):e80425. doi: 10.1371/journal.pone.0080425. eCollection 2013. PLoS One. 2013. PMID: 24312219 Free PMC article.

LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP.

Bennesch MA, Segala G, Wider D, Picard D. Bennesch MA, et al. Among authors: picard d. Nucleic Acids Res. 2016 Oct 14;44(18):8655-8670. doi: 10.1093/nar/gkw522. Epub 2016 Jun 20. Nucleic Acids Res. 2016. PMID: 27325688 Free PMC article.

Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry.

Wider D, Picard D. Wider D, et al. Among authors: picard d. PLoS One. 2017 Dec 8;12(12):e0189403. doi: 10.1371/journal.pone.0189403. eCollection 2017. PLoS One. 2017. PMID: 29220385 Free PMC article.

Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes.

Bhattacharya K, Bernasconi L, Picard D. Bhattacharya K, et al. Among authors: picard d. Sci Rep. 2018 Feb 12;8(1):2801. doi: 10.1038/s41598-018-21210-6. Sci Rep. 2018. PMID: 29434293 Free PMC article.

The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity.

Echeverria PC, Bhattacharya K, Joshi A, Wang T, Picard D. Echeverria PC, et al. Among authors: picard d. PLoS One. 2019 Feb 6;14(2):e0208287. doi: 10.1371/journal.pone.0208287. eCollection 2019. PLoS One. 2019. PMID: 30726209 Free PMC article.

Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling.

Segala G, Bennesch MA, Ghahhari NM, Pandey DP, Echeverria PC, Karch F, Maeda RK, Picard D. Segala G, et al. Among authors: picard d. Nat Commun. 2019 Apr 23;10(1):1833. doi: 10.1038/s41467-019-09800-y. Nat Commun. 2019. PMID: 31015428 Free PMC article.

The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis.

Joshi A, Dai L, Liu Y, Lee J, Ghahhari NM, Segala G, Beebe K, Jenkins LM, Lyons GC, Bernasconi L, Tsai FTF, Agard DA, Neckers L, Picard D. Joshi A, et al. Among authors: picard d. BMC Biol. 2020 Jan 27;18(1):10. doi: 10.1186/s12915-020-0740-7. BMC Biol. 2020. PMID: 31987035 Free PMC article.

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

Bhattacharya K, Weidenauer L, Luengo TM, Pieters EC, Echeverría PC, Bernasconi L, Wider D, Sadian Y, Koopman MB, Villemin M, Bauer C, Rüdiger SGD, Quadroni M, Picard D. Bhattacharya K, et al. Among authors: picard d. Nat Commun. 2020 Nov 25;11(1):5975. doi: 10.1038/s41467-020-19783-w. Nat Commun. 2020. PMID: 33239621 Free PMC article.

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