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Page 1
Design, Synthesis, and Pharmacological Evaluation of Potent Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor (GLP-1R).
Méndez M, Matter H, Defossa E, Kurz M, Lebreton S, Li Z, Lohmann M, Löhn M, Mors H, Podeschwa M, Rackelmann N, Riedel J, Safar P, Thorpe DS, Schäfer M, Weitz D, Breitschopf K. Méndez M, et al. Among authors: podeschwa m. J Med Chem. 2020 Mar 12;63(5):2292-2307. doi: 10.1021/acs.jmedchem.9b01071. Epub 2019 Oct 23. J Med Chem. 2020. PMID: 31596080
Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice.
Pflimlin E, Bielohuby M, Korn M, Breitschopf K, Löhn M, Wohlfart P, Konkar A, Podeschwa M, Bärenz F, Pfenninger A, Schwahn U, Opatz T, Reimann M, Petry S, Tennagels N. Pflimlin E, et al. Among authors: podeschwa m. Cell Metab. 2018 Aug 7;28(2):217-227.e13. doi: 10.1016/j.cmet.2018.05.028. Epub 2018 Jun 21. Cell Metab. 2018. PMID: 29937376 Free article.
Molecular basis for inhibiting human glucose transporters by exofacial inhibitors.
Wang N, Zhang S, Yuan Y, Xu H, Defossa E, Matter H, Besenius M, Derdau V, Dreyer M, Halland N, He KH, Petry S, Podeschwa M, Tennagels N, Jiang X, Yan N. Wang N, et al. Among authors: podeschwa m. Nat Commun. 2022 May 12;13(1):2632. doi: 10.1038/s41467-022-30326-3. Nat Commun. 2022. PMID: 35552392 Free PMC article.
Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway.
Zhang CS, Stratmann A, Block O, Brückner R, Podeschwa M, Altenbach HJ, Wehmeier UF, Piepersberg W. Zhang CS, et al. Among authors: podeschwa m. J Biol Chem. 2002 Jun 21;277(25):22853-62. doi: 10.1074/jbc.M202375200. Epub 2002 Apr 5. J Biol Chem. 2002. PMID: 11937512 Free article.