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Page 1
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk.
Powell SK, O'Shea C, Townsley K, Prytkova I, Dobrindt K, Elahi R, Iskhakova M, Lambert T, Valada A, Liao W, Ho SM, Slesinger PA, Huckins LM, Akbarian S, Brennand KJ. Powell SK, et al. Among authors: prytkova i. Mol Psychiatry. 2023 May;28(5):1970-1982. doi: 10.1038/s41380-021-01273-0. Epub 2021 Sep 7. Mol Psychiatry. 2023. PMID: 34493831 Free PMC article.
Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons.
Popova D, Gameiro-Ros I, Youssef MM, Zalamea P, Morris AD, Prytkova I, Jadali A, Kwan KY, Kamarajan C, Salvatore JE, Xuei X, Chorlian DB, Porjesz B, Kuperman S, Dick DM, Goate A, Edenberg HJ, Tischfield JA, Pang ZP, Slesinger PA, Hart RP. Popova D, et al. Among authors: prytkova i. Mol Psychiatry. 2023 Feb;28(2):746-758. doi: 10.1038/s41380-022-01818-x. Epub 2022 Oct 7. Mol Psychiatry. 2023. PMID: 36207584 Free PMC article.
5. Collaborative Study on the Genetics of Alcoholism: Functional genomics.
Gameiro-Ros I, Popova D, Prytkova I, Pang ZP, Liu Y, Dick D, Bucholz KK, Agrawal A, Porjesz B, Goate AM, Xuei X, Kamarajan C; COGA Collaborators; Tischfield JA, Edenberg HJ, Slesinger PA, Hart RP. Gameiro-Ros I, et al. Among authors: prytkova i. Genes Brain Behav. 2023 Oct;22(5):e12855. doi: 10.1111/gbb.12855. Epub 2023 Aug 2. Genes Brain Behav. 2023. PMID: 37533187 Free PMC article. Review.
Phenotypic complexities of rare heterozygous neurexin-1 deletions.
Fernando MB, Fan Y, Zhang Y, Tokolyi A, Murphy AN, Kammourh S, Deans PJM, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Williams SE, Flaherty EK, Prytkova IA, Cao L, Knowles DA, Fang G, Slesinger PA, Brennand KJ. Fernando MB, et al. Among authors: prytkova ia. Nature. 2025 Apr 9. doi: 10.1038/s41586-025-08864-9. Online ahead of print. Nature. 2025. PMID: 40205044
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Knight KM, Krumm BE, Kapolka NJ, Ludlam WG, Cui M, Mani S, Prytkova I, Obarow EG, Lefevre TJ, Wei W, Ma N, Huang XP, Fay JF, Vaidehi N, Smrcka AV, Slesinger PA, Logothetis DE, Martemyanov KA, Roth BL, Dohlman HG. Knight KM, et al. Among authors: prytkova i. Nat Commun. 2024 Aug 5;15(1):6643. doi: 10.1038/s41467-024-50964-z. Nat Commun. 2024. PMID: 39103320 Free PMC article.
Phenotypic complexities of rare heterozygous neurexin-1 deletions.
Fernando MB, Fan Y, Zhang Y, Tokolyi A, Murphy AN, Kammourh S, Michael Deans PJ, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Williams S, Flaherty EK, Prytkova IA, Cao L, Knowles DA, Fang G, Slesinger PA, Brennand KJ. Fernando MB, et al. Among authors: prytkova ia. bioRxiv [Preprint]. 2024 Nov 1:2023.10.28.564543. doi: 10.1101/2023.10.28.564543. bioRxiv. 2024. Update in: Nature. 2025 Apr 9. doi: 10.1038/s41586-025-08864-9. PMID: 37961635 Free PMC article. Updated. Preprint.
Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons.
Prytkova I, Liu Y, Fernando M, Gameiro-Ros I, Popova D, Kamarajan C, Xuei X, Chorlian DB, Edenberg HJ, Tischfield JA, Porjesz B, Pang ZP, Hart RP, Goate A, Slesinger PA. Prytkova I, et al. bioRxiv [Preprint]. 2024 Jan 13:2023.03.22.533236. doi: 10.1101/2023.03.22.533236. bioRxiv. 2024. Update in: J Neurosci. 2024 Apr 17;44(16):e0918232024. doi: 10.1523/JNEUROSCI.0918-23.2024. PMID: 36993693 Free PMC article. Updated. Preprint.
12 results