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XPRESSO: Rapid genetic engineering of human pluripotent stem cells for durable overexpression using a modular anti-silencing vector.
Wexler Y, Grinstein H, Huber I, Glatstein S, Ghiringhelli M, Edri O, Landesberg M, Shiff D, Arbel G, Rosh I, Choudhary A, Stern S, Gepstein L. Wexler Y, et al. Among authors: rosh i. Stem Cell Reports. 2025 Oct 14;20(10):102603. doi: 10.1016/j.stemcr.2025.102603. Epub 2025 Aug 21. Stem Cell Reports. 2025. PMID: 40845851 Free PMC article.
Shank3 mutation impairs glutamate signaling and myelination in ASD mouse model and human iPSC-derived OPCs.
Fischer I, Shohat S, Leichtmann-Bardoogo Y, Nayak R, Wiener G, Rosh I, Shemen A, Tripathi U, Rokach M, Bar E, Hussein Y, Castro AC, Chen G, Soffer A, Schokoroy-Trangle S, Elad-Sfadia G, Assaf Y, Schroeder A, Monteiro P, Stern S, Maoz BM, Barak B. Fischer I, et al. Among authors: rosh i. Sci Adv. 2024 Oct 11;10(41):eadl4573. doi: 10.1126/sciadv.adl4573. Epub 2024 Oct 11. Sci Adv. 2024. PMID: 39392881 Free PMC article.
Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission.
Stern S, Zhang L, Wang M, Wright R, Rosh I, Hussein Y, Stern T, Choudhary A, Tripathi U, Reed P, Sadis H, Nayak R, Shemen A, Agarwal K, Cordeiro D, Peles D, Hang Y, Mendes APD, Baul TD, Roth JG, Coorapati S, Boks MP, McCombie WR, Hulshoff Pol H, Brennand KJ, Réthelyi JM, Kahn RS, Marchetto MC, Gage FH. Stern S, et al. Among authors: rosh i. Mol Psychiatry. 2024 Oct;29(10):3208-3222. doi: 10.1038/s41380-024-02561-1. Epub 2024 May 4. Mol Psychiatry. 2024. PMID: 38704507 Free PMC article.
NGLY1 mutations cause protein aggregation in human neurons.
Manole A, Wong T, Rhee A, Novak S, Chin SM, Tsimring K, Paucar A, Williams A, Newmeyer TF, Schafer ST, Rosh I, Kaushik S, Hoffman R, Chen S, Wang G, Snyder M, Cuervo AM, Andrade L, Manor U, Lee K, Jones JR, Stern S, Marchetto MC, Gage FH. Manole A, et al. Among authors: rosh i. Cell Rep. 2023 Dec 26;42(12):113466. doi: 10.1016/j.celrep.2023.113466. Epub 2023 Nov 30. Cell Rep. 2023. PMID: 38039131 Free PMC article.
Brain-Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease.
Sela M, Poley M, Mora-Raimundo P, Kagan S, Avital A, Kaduri M, Chen G, Adir O, Rozencweig A, Weiss Y, Sade O, Leichtmann-Bardoogo Y, Simchi L, Aga-Mizrachi S, Bell B, Yeretz-Peretz Y, Or AZ, Choudhary A, Rosh I, Cordeiro D, Cohen-Adiv S, Berdichevsky Y, Odeh A, Shklover J, Shainsky-Roitman J, Schroeder JE, Hershkovitz D, Hasson P, Ashkenazi A, Stern S, Laviv T, Ben-Zvi A, Avital A, Ashery U, Maoz BM, Schroeder A. Sela M, et al. Among authors: rosh i. Adv Mater. 2023 Dec;35(51):e2304654. doi: 10.1002/adma.202304654. Epub 2023 Oct 27. Adv Mater. 2023. PMID: 37753928 Free PMC article.
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