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Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies.
Brindisi M, Senger J, Cavella C, Grillo A, Chemi G, Gemma S, Cucinella DM, Lamponi S, Sarno F, Iside C, Nebbioso A, Novellino E, Shaik TB, Romier C, Herp D, Jung M, Butini S, Campiani G, Altucci L, Brogi S. Brindisi M, et al. Among authors: sarno f. Eur J Med Chem. 2018 Sep 5;157:127-138. doi: 10.1016/j.ejmech.2018.07.069. Epub 2018 Jul 31. Eur J Med Chem. 2018. PMID: 30092367
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease.
De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A. De Simone A, et al. Among authors: sarno f. ACS Med Chem Lett. 2019 Feb 4;10(4):469-474. doi: 10.1021/acsmedchemlett.8b00507. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996781 Free PMC article.
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Zwergel C, Schnekenburger M, Sarno F, Battistelli C, Manara MC, Stazi G, Mazzone R, Fioravanti R, Gros C, Ausseil F, Florean C, Nebbioso A, Strippoli R, Ushijima T, Scotlandi K, Tripodi M, Arimondo PB, Altucci L, Diederich M, Mai A, Valente S. Zwergel C, et al. Among authors: sarno f. Clin Epigenetics. 2019 May 6;11(1):68. doi: 10.1186/s13148-019-0663-8. Clin Epigenetics. 2019. PMID: 31060628 Free PMC article.
Correction to "Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease".
De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A. De Simone A, et al. Among authors: sarno f. ACS Med Chem Lett. 2019 Aug 6;10(9):1357. doi: 10.1021/acsmedchemlett.9b00316. eCollection 2019 Sep 12. ACS Med Chem Lett. 2019. PMID: 31531210 Free PMC article.
62 results