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Page 1
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging.
Snieckute G, Ryder L, Vind AC, Wu Z, Arendrup FS, Stoneley M, Chamois S, Martinez-Val A, Leleu M, Dreos R, Russell A, Gay DM, Genzor AV, Choi BS, Basse AL, Sass F, Dall M, Dollet LCM, Blasius M, Willis AE, Lund AH, Treebak JT, Olsen JV, Poulsen SS, Pownall ME, Jensen BAH, Clemmensen C, Gerhart-Hines Z, Gatfield D, Bekker-Jensen S. Snieckute G, et al. Among authors: sass f. Science. 2023 Dec 8;382(6675):eadf3208. doi: 10.1126/science.adf3208. Epub 2023 Dec 8. Science. 2023. PMID: 38060659
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S. Snieckute G, et al. Among authors: sass f. Cell Metab. 2022 Dec 6;34(12):2036-2046.e8. doi: 10.1016/j.cmet.2022.10.011. Epub 2022 Nov 15. Cell Metab. 2022. PMID: 36384144 Free PMC article.
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions.
Lund J, Breum AW, Gil C, Falk S, Sass F, Isidor MS, Dmytriyeva O, Ranea-Robles P, Mathiesen CV, Basse AL, Johansen OS, Fadahunsi N, Lund C, Nicolaisen TS, Klein AB, Ma T, Emanuelli B, Kleinert M, Sørensen CM, Gerhart-Hines Z, Clemmensen C. Lund J, et al. Among authors: sass f. Nat Metab. 2023 Apr;5(4):677-698. doi: 10.1038/s42255-023-00780-4. Epub 2023 Apr 13. Nat Metab. 2023. PMID: 37055619
NK2R control of energy expenditure and feeding to treat metabolic diseases.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. Sass F, et al. Nature. 2024 Nov;635(8040):987-1000. doi: 10.1038/s41586-024-08207-0. Epub 2024 Nov 13. Nature. 2024. PMID: 39537932 Free PMC article.
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.
Schlein C, Fischer AW, Sass F, Worthmann A, Tödter K, Jaeckstein MY, Behrens J, Lynes MD, Kiebish MA, Narain NR, Bussberg V, Darkwah A, Jespersen NZ, Nielsen S, Scheele C, Schweizer M, Braren I, Bartelt A, Tseng YH, Heeren J, Scheja L. Schlein C, et al. Cell Rep. 2021 Jan 12;34(2):108624. doi: 10.1016/j.celrep.2020.108624. Cell Rep. 2021. PMID: 33440156 Free PMC article.
Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of interorganellar lipid cycling.
Karavaeva I, Basse AL, Trammell SAJ, Hussain MF, Markussen LK, Havelund JF, Isidor MS, Richter HJ, Chubanava S, Deleye Y, Kaiser Z, Shen Y, Neess D, Sass F, Finger F, Muntadas LA, Tandio D, Ma T, Sustarsic EG, Embring H, Kristensen CK, McIntyre RL, Martinez GJ, Husted AS, Emmett MJ, Kipp ZA, Frost M, Jedrychowski MP, van Weeghel M, Majd H, Zhuravleva E, McGarrah RW, Plucinska K, Midha MK, Prokesch A, Cohen P, Granneman JG, Seale P, Houtkooper RH, Hansen JB, Gygi SP, Schwartz TW, Gillum MP, Hinds TD Jr, Soccio RE, White PJ, Kunji ERS, Moritz T, Treebak JT, Mandrup S, Emanuelli B, Kazak L, Færgeman NJ, Lazar MA, Zachary Gerhart-Hines. Karavaeva I, et al. Among authors: sass f. bioRxiv [Preprint]. 2026 Jun 3:2026.05.30.724257. doi: 10.64898/2026.05.30.724257. bioRxiv. 2026. PMID: 42282667 Free PMC article. Preprint.
28 results