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Sirtuin Inhibitors Are Broadly Antiviral against Arboviruses.
Hackett BA, Dittmar M, Segrist E, Pittenger N, To J, Griesman T, Gordesky-Gold B, Schultz DC, Cherry S. Hackett BA, et al. Among authors: schultz dc. mBio. 2019 Jul 9;10(4):e01446-19. doi: 10.1128/mBio.01446-19. mBio. 2019. PMID: 31289184 Free PMC article.
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2.
Dittmar M, Lee JS, Whig K, Segrist E, Li M, Kamalia B, Castellana L, Ayyanathan K, Cardenas-Diaz FL, Morrisey EE, Truitt R, Yang W, Jurado K, Samby K, Ramage H, Schultz DC, Cherry S. Dittmar M, et al. Among authors: schultz dc. Cell Rep. 2021 Apr 6;35(1):108959. doi: 10.1016/j.celrep.2021.108959. Epub 2021 Mar 23. Cell Rep. 2021. PMID: 33811811 Free PMC article.
Pharmacological activation of STING blocks SARS-CoV-2 infection.
Li M, Ferretti M, Ying B, Descamps H, Lee E, Dittmar M, Lee JS, Whig K, Kamalia B, Dohnalová L, Uhr G, Zarkoob H, Chen YC, Ramage H, Ferrer M, Lynch K, Schultz DC, Thaiss CA, Diamond MS, Cherry S. Li M, et al. Among authors: schultz dc. Sci Immunol. 2021 May 18;6(59):eabi9007. doi: 10.1126/sciimmunol.abi9007. Sci Immunol. 2021. PMID: 34010142 Free PMC article.
Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition.
Liu X, Verma A, Garcia G Jr, Ramage H, Lucas A, Myers RL, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. Liu X, et al. Among authors: schultz dc. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2113401118. doi: 10.1073/pnas.2113401118. Epub 2021 Sep 30. Proc Natl Acad Sci U S A. 2021. PMID: 34593624 Free PMC article.
Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2.
Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Ardanuy J, Taylor L, Lee JS, Li M, Lee E, Shoffler C, Petucci C, Constant S, Ferrer M, Thaiss CA, Frieman MB, Cherry S. Schultz DC, et al. Nature. 2022 Apr;604(7904):134-140. doi: 10.1038/s41586-022-04482-x. Epub 2022 Feb 7. Nature. 2022. PMID: 35130559 Free PMC article.
93 results