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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1953 2
1954 1
1956 1
1959 2
1965 2
1966 1
1968 2
1969 1
1972 1
1973 1
1974 1
1975 3
1976 5
1977 4
1978 11
1979 3
1980 4
1981 1
1982 2
1983 2
1985 1
1986 4
1987 2
1988 5
1989 1
1990 6
1991 4
1992 6
1993 6
1994 5
1995 3
1996 4
1997 1
1998 1
1999 2
2000 6
2001 3
2002 7
2003 14
2004 14
2005 8
2006 8
2007 18
2008 11
2009 24
2010 22
2011 30
2012 38
2013 45
2014 73
2015 66
2016 67
2017 47
2018 55
2019 66
2020 29
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Article type
Publication date

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693 results
Results by year
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Page 1
A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.
Napolitano G, Di Malta C, Esposito A, de Araujo MEG, Pece S, Bertalot G, Matarese M, Benedetti V, Zampelli A, Stasyk T, Siciliano D, Venuta A, Cesana M, Vilardo C, Nusco E, Monfregola J, Calcagnì A, Di Fiore PP, Huber LA, Ballabio A. Napolitano G, et al. Among authors: Esposito A. Nature. 2020 Jul 1. doi: 10.1038/s41586-020-2444-0. Online ahead of print. Nature. 2020. PMID: 32612235
Our findings identify a mechanism that enables differential phosphorylation of mTORC1 substrates, the dysregulation of which leads to kidney cysts and cancer....
Our findings identify a mechanism that enables differential phosphorylation of mTORC1 substrates, the dysregulation of which leads to kidney …
Noninvasive diffusion magnetic resonance imaging of brain tumour cell size for the early detection of therapeutic response.
Roberts TA, Hyare H, Agliardi G, Hipwell B, d'Esposito A, Ianus A, Breen-Norris JO, Ramasawmy R, Taylor V, Atkinson D, Punwani S, Lythgoe MF, Siow B, Brandner S, Rees J, Panagiotaki E, Alexander DC, Walker-Samuel S. Roberts TA, et al. Among authors: d'Esposito A. Sci Rep. 2020 Jun 8;10(1):9223. doi: 10.1038/s41598-020-65956-4. Sci Rep. 2020. PMID: 32514049 Free PMC article.
Cancer cells differ in size from those of their host tissue and are known to change in size during the processes of cell death. ...
Cancer cells differ in size from those of their host tissue and are known to change in size during the processes of cell death. ...
Pharmacological management of male breast cancer.
Duso BA, Trapani D, Marra A, D'Amico P, Guerini Rocco E, Fusco N, Mazzarella L, Criscitiello C, Esposito A, Curigliano G. Duso BA, et al. Among authors: Esposito A. Expert Opin Pharmacother. 2020 Jun 4:1-12. doi: 10.1080/14656566.2020.1763305. Online ahead of print. Expert Opin Pharmacother. 2020. PMID: 32496137
INTRODUCTION: Despite its rarity, male breast cancer shows a steadily rising incidence. Given the absence of ad hoc prospective randomized clinical trials, treatment strategies are based on extrapolation from female breast cancer recommendations or solely on populat …
INTRODUCTION: Despite its rarity, male breast cancer shows a steadily rising incidence. Given the absence of ad hoc prospective rando …
Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer.
Chopra N, Tovey H, Pearson A, Cutts R, Toms C, Proszek P, Hubank M, Dowsett M, Dodson A, Daley F, Kriplani D, Gevensleben H, Davies HR, Degasperi A, Roylance R, Chan S, Tutt A, Skene A, Evans A, Bliss JM, Nik-Zainal S, Turner NC. Chopra N, et al. Among authors: Nik-Zainal S. Nat Commun. 2020 May 29;11(1):2662. doi: 10.1038/s41467-020-16142-7. Nat Commun. 2020. PMID: 32471999 Free PMC article.
Triple negative breast cancer (TNBC) encompasses molecularly different subgroups, with a subgroup harboring evidence of defective homologous recombination (HR) DNA repair. ...
Triple negative breast cancer (TNBC) encompasses molecularly different subgroups, with a subgroup harboring evidence of defective hom …
Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth.
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, Kar G, Vento-Tormo R, Hagai T, Chen X, Haniffa MA, Shields JD, Teichmann SA. Davidson S, et al. Among authors: Shields JD. Cell Rep. 2020 May 19;31(7):107628. doi: 10.1016/j.celrep.2020.107628. Cell Rep. 2020. PMID: 32433953 Free PMC article.
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.
Colom B, Alcolea MP, Piedrafita G, Hall MWJ, Wabik A, Dentro SC, Fowler JC, Herms A, King C, Ong SH, Sood RK, Gerstung M, Martincorena I, Hall BA, Jones PH. Colom B, et al. Among authors: Hall MWJ, Hall BA, Jones PH. Nat Genet. 2020 Jun;52(6):604-614. doi: 10.1038/s41588-020-0624-3. Epub 2020 May 18. Nat Genet. 2020. PMID: 32424351
Despite their relevance for understanding aging and cancer, the processes that underpin mutational selection in normal tissues remain poorly understood. ...
Despite their relevance for understanding aging and cancer, the processes that underpin mutational selection in normal tissues remain …
Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation.
Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MH, Caldwell ST, Logan A, Pala L, Hartley RC, Frezza C, Saeb-Parsy K, Murphy MP. Martin JL, et al. Among authors: Frezza C. Nat Metab. 2019 Sep 30;1:966-974. doi: 10.1038/s42255-019-0115-y. Nat Metab. 2019. PMID: 32395697 Free PMC article.
Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions.
Thompson O, von Meyenn F, Hewitt Z, Alexander J, Wood A, Weightman R, Gregory S, Krueger F, Andrews S, Barbaric I, Gokhale PJ, Moore HD, Reik W, Milo M, Nik-Zainal S, Yusa K, Andrews PW. Thompson O, et al. Among authors: Nik-Zainal S. Nat Commun. 2020 Mar 23;11(1):1528. doi: 10.1038/s41467-020-15271-3. Nat Commun. 2020. PMID: 32251294 Free PMC article.
Melanoma immunotherapy: strategies to overcome pharmacological resistance.
Trojaniello C, Vitale MG, Scarpato L, Esposito A, Ascierto PA. Trojaniello C, et al. Among authors: Esposito A. Expert Rev Anticancer Ther. 2020 Apr;20(4):289-304. doi: 10.1080/14737140.2020.1745634. Epub 2020 Apr 6. Expert Rev Anticancer Ther. 2020. PMID: 32195606
693 results
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