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23 results
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Sox2 modulation increases naïve pluripotency plasticity.
Tremble KC, Stirparo GG, Bates LE, Maskalenka K, Stuart HT, Jones K, Andersson-Rolf A, Radzisheuskaya A, Koo BK, Bertone P, Silva JCR. Tremble KC, et al. Among authors: stirparo gg. iScience. 2021 Feb 6;24(3):102153. doi: 10.1016/j.isci.2021.102153. eCollection 2021 Mar 19. iScience. 2021. PMID: 33665571 Free PMC article.
Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.
Stuart HT, Stirparo GG, Lohoff T, Bates LE, Kinoshita M, Lim CY, Sousa EJ, Maskalenka K, Radzisheuskaya A, Malcolm AA, Alves MRP, Lloyd RL, Nestorowa S, Humphreys P, Mansfield W, Reik W, Bertone P, Nichols J, Göttgens B, Silva JCR. Stuart HT, et al. Among authors: stirparo gg. Cell Stem Cell. 2019 Sep 5;25(3):388-406.e8. doi: 10.1016/j.stem.2019.07.009. Epub 2019 Aug 15. Cell Stem Cell. 2019. PMID: 31422912 Free PMC article.
OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms.
Stirparo GG, Kurowski A, Yanagida A, Bates LE, Strawbridge SE, Hladkou S, Stuart HT, Boroviak TE, Silva JCR, Nichols J. Stirparo GG, et al. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2008890118. doi: 10.1073/pnas.2008890118. Proc Natl Acad Sci U S A. 2021. PMID: 33452132 Free PMC article.
Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency.
Kinoshita M, Barber M, Mansfield W, Cui Y, Spindlow D, Stirparo GG, Dietmann S, Nichols J, Smith A. Kinoshita M, et al. Among authors: stirparo gg. Cell Stem Cell. 2021 Mar 4;28(3):453-471.e8. doi: 10.1016/j.stem.2020.11.005. Epub 2020 Dec 2. Cell Stem Cell. 2021. PMID: 33271069 Free PMC article.
Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency.
Bredenkamp N, Yang J, Clarke J, Stirparo GG, von Meyenn F, Dietmann S, Baker D, Drummond R, Ren Y, Li D, Wu C, Rostovskaya M, Eminli-Meissner S, Smith A, Guo G. Bredenkamp N, et al. Among authors: stirparo gg. Stem Cell Reports. 2019 Dec 10;13(6):1083-1098. doi: 10.1016/j.stemcr.2019.10.009. Epub 2019 Nov 7. Stem Cell Reports. 2019. PMID: 31708477 Free PMC article.
Metabolic control of DNA methylation in naive pluripotent cells.
Betto RM, Diamante L, Perrera V, Audano M, Rapelli S, Lauria A, Incarnato D, Arboit M, Pedretti S, Rigoni G, Guerineau V, Touboul D, Stirparo GG, Lohoff T, Boroviak T, Grumati P, Soriano ME, Nichols J, Mitro N, Oliviero S, Martello G. Betto RM, et al. Among authors: stirparo gg. Nat Genet. 2021 Feb;53(2):215-229. doi: 10.1038/s41588-020-00770-2. Epub 2021 Feb 1. Nat Genet. 2021. PMID: 33526924 Free PMC article.
Human naive epiblast cells possess unrestricted lineage potential.
Guo G, Stirparo GG, Strawbridge SE, Spindlow D, Yang J, Clarke J, Dattani A, Yanagida A, Li MA, Myers S, Özel BN, Nichols J, Smith A. Guo G, et al. Among authors: stirparo gg. Cell Stem Cell. 2021 Apr 3:S1934-5909(21)00076-X. doi: 10.1016/j.stem.2021.02.025. Online ahead of print. Cell Stem Cell. 2021. PMID: 33831366
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