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123 results

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Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade.
Woess K, Macho-Maschler S, Van Ingen Schenau DS, Butler M, Lassnig C, Valcanover D, Poelzl A, Meissl K, Maurer B, Brandstoetter T, Vogl C, Koren A, Kubicek S, Orlova A, Moriggl R, Strobl B, Sexl V, Van Leeuwen FN, Kuiper RP, Mueller M. Woess K, et al. Among authors: strobl b. Haematologica. 2023 Apr 1;108(4):993-1005. doi: 10.3324/haematol.2021.279848. Haematologica. 2023. PMID: 35021603 Free PMC article.
TYK2: An Upstream Kinase of STATs in Cancer.
Wöss K, Simonović N, Strobl B, Macho-Maschler S, Müller M. Wöss K, et al. Among authors: strobl b. Cancers (Basel). 2019 Nov 5;11(11):1728. doi: 10.3390/cancers11111728. Cancers (Basel). 2019. PMID: 31694222 Free PMC article. Review.
TYK2 licenses non-canonical inflammasome activation during endotoxemia.
Poelzl A, Lassnig C, Tangermann S, Hromadová D, Reichart U, Gawish R, Mueller K, Moriggl R, Linkermann A, Glösmann M, Kenner L, Mueller M, Strobl B. Poelzl A, et al. Among authors: strobl b. Cell Death Differ. 2021 Feb;28(2):748-763. doi: 10.1038/s41418-020-00621-x. Epub 2020 Sep 14. Cell Death Differ. 2021. PMID: 32929218 Free PMC article.
In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity.
Prchal-Murphy M, Witalisz-Siepracka A, Bednarik KT, Putz EM, Gotthardt D, Meissl K, Sexl V, Müller M, Strobl B. Prchal-Murphy M, et al. Among authors: strobl b. Oncoimmunology. 2015 May 26;4(11):e1047579. doi: 10.1080/2162402X.2015.1047579. eCollection 2015 Nov. Oncoimmunology. 2015. PMID: 26451322 Free PMC article.
The good and the bad faces of STAT1 in solid tumours.
Meissl K, Macho-Maschler S, Müller M, Strobl B. Meissl K, et al. Among authors: strobl b. Cytokine. 2017 Jan;89:12-20. doi: 10.1016/j.cyto.2015.11.011. Epub 2015 Nov 26. Cytokine. 2017. PMID: 26631912 Free article. Review.
TYK2 in Tumor Immunosurveillance.
Karjalainen A, Shoebridge S, Krunic M, Simonović N, Tebb G, Macho-Maschler S, Strobl B, Müller M. Karjalainen A, et al. Among authors: strobl b. Cancers (Basel). 2020 Jan 8;12(1):150. doi: 10.3390/cancers12010150. Cancers (Basel). 2020. PMID: 31936322 Free PMC article. Review.
STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity.
Meissl K, Simonović N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, Puga A, Vogl C, Poelzl A, Bosmann M, Dohnal A, Sexl V, Müller M, Strobl B. Meissl K, et al. Among authors: strobl b. Front Immunol. 2020 Sep 11;11:2189. doi: 10.3389/fimmu.2020.02189. eCollection 2020. Front Immunol. 2020. PMID: 33042133 Free PMC article.
123 results