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Page 1
Transcriptomic, Specific Marker, and Pathway Analysis of Smooth Muscle Cell Foam Cells Compared to Macrophage Foam Cells in Human Atherosclerosis.
Allahverdian S, Mao Y, Xiang P, Blanchard V, Bölük A, Hart PA, Cheng P, Li DY, Worssam MD, Arasu UT, Taipale M, Kiema M, Laakkonen JP, Örd T, Kaikkonen MU, Miller CL, Quertermous T, Chan T, Francis GA. Allahverdian S, et al. Among authors: taipale m. bioRxiv [Preprint]. 2026 Jun 1:2026.05.27.728334. doi: 10.64898/2026.05.27.728334. bioRxiv. 2026. PMID: 42282821 Free PMC article. Preprint.
Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype.
Perry RN, Lenert G, Benavente ED, Bölük A, Hernandez R, Ma L, Barbera N, Watts K, Mendoza VD, Örd T, Taipale M, Sachs N, Pauli J, Mokry M, de Kleijn DPV, de Winther MPJ, Mayr M, Maegdefessel L, Reue K, Kaikkonen MU, Björkegren JLM, den Ruijter HM, Civelek M. Perry RN, et al. Among authors: taipale m. Circ Res. 2026 May 8;138(10):e326941. doi: 10.1161/CIRCRESAHA.125.326941. Epub 2026 Apr 15. Circ Res. 2026. PMID: 41983287 Free PMC article.
Toward a biopsy-free approach: cardiac magnetic resonance T1 mapping for detecting heart transplant rejection.
Taipale M, Pentikäinen M, Martelius L, Mutka A, Kytölä S, Kankainen M, Peltonen JI, Syrjälä S, Lahtiharju A, Lommi J, Jahnukainen T, Lemström K, Ojala T. Taipale M, et al. Eur Heart J Cardiovasc Imaging. 2026 Jun 1;27(6):1284-1286. doi: 10.1093/ehjci/jeag080. Eur Heart J Cardiovasc Imaging. 2026. PMID: 41886609 Free PMC article. No abstract available.
A scalable approach to resolving variants of uncertain significance.
Tejura M, Chen Y, McEwen AE, Stewart R, Sverchkov Y, Laval F, Woo I, Zeiberg D, Shen R, Fayer S, Stone J, Smith N, Casadei S, Wang ZR, Snyder MW, Capodanno BJ, Gupta P, Benazouz M, Jain S, Heidl S, Muffley L, Dong S, Hitz BC, Gabdank I, Lin K, Da EY, Best S, Grindstaff S, Reinhart D, Rodriguez-Salas L, Seid O, Vandi AJ, Wenman C, Wheelock MK, Pendyala S, Holmes D, Xu A, Hosokai A, Tixhon M, Reno C, Ewald JD, Spirohn-Fitzgerald K, Teelucksingh T, Hao T, Chen ZS, Haghighi M, Hamid AK, Miglietta EA, Weisbart E, Coppin G, Lambourne L, Gebbia M, Coté AG, van Loggerenberg W, Fawcett KM, Steiner RD, Johnsen JM, Stergachis AB, Iakoucheva LM, Singh S, Cimini BA, Roth FP, James RG; IGVF Coding Variants Focus Group; Vidal M, Taipale M, Carpenter AE, Calderwood MA, Craven M, Pejaver V, Rubin AF, Radivojac P, Fowler DM, Starita LM. Tejura M, et al. Among authors: taipale m. bioRxiv [Preprint]. 2026 Feb 23:2026.02.14.705848. doi: 10.64898/2026.02.14.705848. bioRxiv. 2026. PMID: 41727046 Free PMC article. Preprint.
Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways.
Pachano T, Leng H, Dugied G, Tribble T, Loubiere V, Rauh F, Lee Y, Schleiffer A, Young V, Weller B, Lyons EA, Hass MR, Kottayan LC, Weirauch MT, Fuxman Bass JI, Newton HJ, Ensminger AW, Braun PF, Schramek D, Stark A, Taipale M. Pachano T, et al. Among authors: taipale m. bioRxiv [Preprint]. 2025 Nov 17:2025.11.17.687821. doi: 10.1101/2025.11.17.687821. bioRxiv. 2025. PMID: 41332698 Free PMC article. Preprint.
Single-cell to pre-clinical evaluation of Trem2, Folr2, and Slc7a7 as macrophage-associated biomarkers for atherosclerosis.
Örd T, Palani S, Giroud Gerbetant J, Bodoy S, Lönnberg T, Niskanen H, Ravindran A, Holappa L, Chemaly M, Taipale M, Õunap K, Haikonen R, Talukdar H, Sukhavasi K, Liljenbäck H, Virta J, Ruotsalainen AK, Pierrot-Blanchet C, Miner MWG, Moisio O, Rajala N, Li XG, Low PS, Saraste A, Heinäniemi M, Ylä-Herttuala S, Björkegren JLM, Hedin U, Matic L, Yvan-Charvet L, Palacín M, Roivainen A, Kaikkonen MU. Örd T, et al. Among authors: taipale m. Cardiovasc Res. 2025 Dec 18;121(16):2503-2519. doi: 10.1093/cvr/cvaf210. Cardiovasc Res. 2025. PMID: 41206594 Free PMC article.
Comprehensively Testing the Function of Missense Variation in the STK11 Tumour Suppressor.
Zimmerman D, Cote A, van Loggerenberg W, Gebbia M, Kishore N, Weile J, Li R, Reno C, Marsh AP, Hernandez F, Shahagadkar P, Grove L, Meier SR, Wu HJ, Fenoglio S, Ahronian L, Teng T, Waters AJ, Seward D, Taipale M, Aronson M, Richardson ME, Adams DJ, Roth FP. Zimmerman D, et al. Among authors: taipale m. bioRxiv [Preprint]. 2025 Jul 18:2025.07.14.664734. doi: 10.1101/2025.07.14.664734. bioRxiv. 2025. PMID: 40791513 Free PMC article. Preprint.
Drug-Free Approach to Regulate Undruggable Proto-Oncogene MYC Using Biomimetic Porous Nanoparticles for Cancer Immunotherapy.
Happonen E, Dang Y, Wang J, Saarela S, Sivonen M, Zakir M, Laari MI, Constantinou Y, Tamarov K, Hakkarainen H, Montaser AB, Leinonen H, Küblbeck J, Örd T, Taipale M, Kaikkonen M, Liu R, Klefström J, Yu H, Xu Z, Lehto VP, Xu W. Happonen E, et al. Among authors: taipale m. ACS Appl Mater Interfaces. 2025 Aug 20;17(33):46521-46534. doi: 10.1021/acsami.5c05042. Epub 2025 Aug 11. ACS Appl Mater Interfaces. 2025. PMID: 40789210
123 results