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Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice.
Nasello C, Poppi LA, Wu J, Kowalski TF, Thackray JK, Wang R, Persaud A, Mahboob M, Lin S, Spaseska R, Johnson CK, Gordon D, Tissir F, Heiman GA, Tischfield JA, Bocarsly M, Tischfield MA. Nasello C, et al. Among authors: tischfield ma, tischfield ja. bioRxiv [Preprint]. 2023 Nov 28:2023.11.28.569034. doi: 10.1101/2023.11.28.569034. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2307156121. doi: 10.1073/pnas.2307156121. PMID: 38077033 Free PMC article. Updated. Preprint.
SIRT7 and p53 interaction in embryonic development and tumorigenesis.
Vazquez BN, Fernández-Duran I, Hernandez Y, Tarighi S, Thackray JK, Espinosa-Alcantud M, Kumari P, Ianni A, Cesaire L, Braun T, Esteller M, Tischfield J, Vaquero A, Serrano L. Vazquez BN, et al. Front Cell Dev Biol. 2024 Jan 3;11:1281730. doi: 10.3389/fcell.2023.1281730. eCollection 2023. Front Cell Dev Biol. 2024. PMID: 38234684 Free PMC article.
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5.
Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray JK, Ray C, Berenguer C, Kumari P, Bech JJ, Braun T, Ianni A, Tischfield JA, Serrano L, Esteller M, Sardina JL, De La Torre C, Sigvardsson M, Vazquez BN, Vaquero A. Gamez-Garcia A, et al. Among authors: tischfield ja. Nat Immunol. 2024 Dec;25(12):2308-2319. doi: 10.1038/s41590-024-01995-7. Epub 2024 Oct 18. Nat Immunol. 2024. PMID: 39424985 Free PMC article.
A Celsr3 Mutation Linked to Tourette Disorder Disrupts Cortical Dendritic Patterning and Striatal Cholinergic Interneuron Excitability.
Nasello C, Yilmaz GD, Poppi LA, Kowalski TF, Ho-Nguyen KT, Wu J, Matrongolo M, Thackray JK, Shi A, Carayannopoulos NL, Cheedalla N, McGinnis J, Chen J, Khondker A, Tissir F, Heiman GA, Tischfield JA, Tischfield MA. Nasello C, et al. Among authors: tischfield ja. Int J Mol Sci. 2025 Oct 23;26(21):10307. doi: 10.3390/ijms262110307. Int J Mol Sci. 2025. PMID: 41226347 Free PMC article.
Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder.
Green NC, Gao H, Chu X, Yuan Q, McGuire P, Lai D, Jiang G, Xuei X, Reiter JL, Stevens J, Sutherland GT, Goate AM, Pang ZP, Slesinger PA, Hart RP, Tischfield JA, Agrawal A, Wang Y, Duren Z, Edenberg HJ, Liu Y. Green NC, et al. Among authors: tischfield ja. Nat Commun. 2025 Oct 13;16(1):9070. doi: 10.1038/s41467-025-64136-0. Nat Commun. 2025. PMID: 41083468 Free PMC article.
Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders.
Strom NI, Halvorsen MW, Grove J, Ásbjörnsdóttir B, Luðvígsson P, Thorarensen Ó, de Schipper E, Bäckmann J, Andrén P, Tian C; PGC TS Working Group; 23andMe Research Team; Als TD, Nissen JB, Meier SM, Bybjerg-Grauholm J, Hougaard DM, Werge T, Børglum AD, Hinds DA, Rück C, Mataix-Cols D, Stefánsson H, Stefansson K, Crowley JJ, Mattheisen M. Strom NI, et al. Biol Psychiatry. 2025 Apr 1;97(7):743-752. doi: 10.1016/j.biopsych.2024.07.025. Epub 2024 Oct 9. Biol Psychiatry. 2025. PMID: 39389409 Free article.
Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.
Green N, Gao H, Chu X, Yuan Q, McGuire P, Lai D, Jiang G, Xuei X, Reiter JL, Stevens J, Sutherland GT, Goate AM, Pang ZP, Slesinger PA, Hart RP, Tischfield JA, Agrawal A, Wang Y, Duren Z, Edenberg HJ, Liu Y. Green N, et al. Among authors: tischfield ja. bioRxiv [Preprint]. 2024 Oct 31:2024.08.02.606355. doi: 10.1101/2024.08.02.606355. bioRxiv. 2024. Update in: Nat Commun. 2025 Oct 13;16(1):9070. doi: 10.1038/s41467-025-64136-0. PMID: 39149227 Free PMC article. Updated. Preprint.
Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice.
Nasello C, Poppi LA, Wu J, Kowalski TF, Thackray JK, Wang R, Persaud A, Mahboob M, Lin S, Spaseska R, Johnson CK, Gordon D, Tissir F, Heiman GA, Tischfield JA, Bocarsly M, Tischfield MA. Nasello C, et al. Among authors: tischfield ja. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2307156121. doi: 10.1073/pnas.2307156121. Epub 2024 Apr 29. Proc Natl Acad Sci U S A. 2024. PMID: 38683996 Free PMC article.
243 results