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YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.
Fan PD, Narzisi G, Jayaprakash AD, Venturini E, Robine N, Smibert P, Germer S, Yu HA, Jordan EJ, Paik PK, Janjigian YY, Chaft JE, Wang L, Jungbluth AA, Middha S, Spraggon L, Qiao H, Lovly CM, Kris MG, Riely GJ, Politi K, Varmus H, Ladanyi M. Fan PD, et al. Among authors: varmus h. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E6030-E6038. doi: 10.1073/pnas.1717782115. Epub 2018 Jun 6. Proc Natl Acad Sci U S A. 2018. PMID: 29875142 Free PMC article.
The new era in cancer research.
Varmus H. Varmus H. Science. 2006 May 26;312(5777):1162-5. doi: 10.1126/science.1126758. Science. 2006. PMID: 16728627
The transformation of oncology.
Varmus H. Varmus H. Science. 2016 Apr 8;352(6282):123. doi: 10.1126/science.aaf7301. Science. 2016. PMID: 27124426 No abstract available.
Insurance for broad genomic tests in oncology.
Eisenberg R, Varmus H. Eisenberg R, et al. Among authors: varmus h. Science. 2017 Dec 1;358(6367):1133-1134. doi: 10.1126/science.aao6708. Science. 2017. PMID: 29191895 No abstract available.
A Prize for Cancer Prevention.
Varmus H. Varmus H. Cell. 2017 Sep 21;171(1):14-17. doi: 10.1016/j.cell.2017.08.020. Epub 2017 Sep 6. Cell. 2017. PMID: 28888324 Free article.
Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.
de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, Varmus H, Bernards R, Smit EF, Politi K, Downward J. de Bruin EC, et al. Among authors: varmus h. Cancer Discov. 2014 May;4(5):606-19. doi: 10.1158/2159-8290.CD-13-0741. Epub 2014 Feb 17. Cancer Discov. 2014. PMID: 24535670 Free PMC article.
444 results