Vaughn LS - Search Results

1

Toll-like Receptor (TLR)-induced Rasgef1b expression in macrophages is regulated by NF-κB through its proximal promoter.

Leão FB, Vaughn LS, Bhatt D, Liao W, Maloney D, Carvalho BC, Oliveira L, Ghosh S, Silva AM. Leão FB, et al. Among authors: vaughn ls. Int J Biochem Cell Biol. 2020 Oct;127:105840. doi: 10.1016/j.biocel.2020.105840. Epub 2020 Aug 28. Int J Biochem Cell Biol. 2020. PMID: 32866686 Free article.

2

A truncated PACT protein resulting from a frameshift mutation reported in movement disorder DYT16 triggers caspase activation and apoptosis.

Burnett SB, Vaughn LS, Strom JM, Francois A, Patel RC. Burnett SB, et al. Among authors: vaughn ls. J Cell Biochem. 2019 Nov;120(11):19004-19018. doi: 10.1002/jcb.29223. Epub 2019 Jun 27. J Cell Biochem. 2019. PMID: 31246344 Free PMC article.

3

Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT.

Vaughn LS, Bragg DC, Sharma N, Camargos S, Cardoso F, Patel RC. Vaughn LS, et al. J Biol Chem. 2015 Sep 11;290(37):22543-57. doi: 10.1074/jbc.M115.669408. Epub 2015 Jul 31. J Biol Chem. 2015. PMID: 26231208 Free PMC article.

4

Dystonia 16 (DYT16) mutations in PACT cause dysregulated PKR activation and eIF2α signaling leading to a compromised stress response.

Burnett SB, Vaughn LS, Sharma N, Kulkarni R, Patel RC. Burnett SB, et al. Among authors: vaughn ls. Neurobiol Dis. 2020 Dec;146:105135. doi: 10.1016/j.nbd.2020.105135. Epub 2020 Oct 10. Neurobiol Dis. 2020. PMID: 33049316 Free PMC article.

5

DYT-PRKRA Mutation P222L Enhances PACT's Stimulatory Activity on Type I Interferon Induction.

Vaughn LS, Frederick K, Burnett SB, Sharma N, Bragg DC, Camargos S, Cardoso F, Patel RC. Vaughn LS, et al. Biomolecules. 2022 May 17;12(5):713. doi: 10.3390/biom12050713. Biomolecules. 2022. PMID: 35625640 Free PMC article.

6

Inhibition of PKR protects against tunicamycin-induced apoptosis in neuroblastoma cells.

Vaughn LS, Snee B, Patel RC. Vaughn LS, et al. Gene. 2014 Feb 15;536(1):90-6. doi: 10.1016/j.gene.2013.11.074. Epub 2013 Dec 14. Gene. 2014. PMID: 24334130

7

Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling.

Vaughn LS, Chukwurah E, Patel RC. Vaughn LS, et al. Biochem J. 2021 Feb 12;478(3):493-510. doi: 10.1042/BCJ20200987. Biochem J. 2021. PMID: 33459340 Free PMC article.

8

Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs.

Patel P, Buchanan CN, Zdradzinski MD, Sahoo PK, Kar AN, Lee SJ, Vaughn LS, Urisman A, Oses-Prieto J, Dell'Orco M, Cassidy DE, Costa ID, Miller S, Thames E, Smith TP, Burlingame AL, Perrone-Bizzozero N, Twiss JL. Patel P, et al. Among authors: vaughn ls. Nucleic Acids Res. 2022 Jun 10;50(10):5772-5792. doi: 10.1093/nar/gkac337. Nucleic Acids Res. 2022. PMID: 35556128 Free PMC article.

9

KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization.

Olguin SL, Patel P, Buchanan CN, Dell'Orco M, Gardiner AS, Cole R, Vaughn LS, Sundararajan A, Mudge J, Allan AM, Ortinski P, Brigman JL, Twiss JL, Perrone-Bizzozero NI. Olguin SL, et al. Among authors: vaughn ls. Commun Biol. 2022 Jul 7;5(1):672. doi: 10.1038/s42003-022-03594-4. Commun Biol. 2022. PMID: 35798971 Free PMC article.

10

Acetylation of Axonal G3BP1 through ELP3 Accelerates Axon Regeneration.

Costa ID, Michenfelder E, Siciliano S, Tapita A, Buchanan CN, Vaughn LS, Lee J, Oses-Prieto J, Ma C, Thames E, Samra N, Ben-Dor S, Haffner-Krausz R, McElveen M, Smith TP, Nawar N, Manaswiyoungkul P, Gunning PT, Fainzilber M, Burlingame AL, Zhu H, Perlson E, Sahoo PK, Twiss JL. Costa ID, et al. Among authors: vaughn ls. bioRxiv [Preprint]. 2025 Oct 30:2025.10.28.685144. doi: 10.1101/2025.10.28.685144. bioRxiv. 2025. PMID: 41279176 Free PMC article. Preprint.

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