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Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice.
Tan MWY, Sng MK, Cheng HS, Low ZS, Leong BJJ, Chua D, Tan EHP, Chan JSK, Yip YS, Lee YH, Pal M, Wang X, Wahli W, Tan NS. Tan MWY, et al. Among authors: Wahli W. Cell Death Differ. 2020 Apr 20. doi: 10.1038/s41418-020-0535-y. Online ahead of print. Cell Death Differ. 2020. PMID: 32313198
Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity.
Régnier M, Polizzi A, Smati S, Lukowicz C, Fougerat A, Lippi Y, Fouché E, Lasserre F, Naylies C, Bétoulières C, Barquissau V, Mouisel E, Bertrand-Michel J, Batut A, Saati TA, Canlet C, Tremblay-Franco M, Ellero-Simatos S, Langin D, Postic C, Wahli W, Loiseau N, Guillou H, Montagner A. Régnier M, et al. Among authors: Wahli W. Sci Rep. 2020 Apr 16;10(1):6489. doi: 10.1038/s41598-020-63579-3. Sci Rep. 2020. PMID: 32300166 Free PMC article.
Collaborative Regulation of LRG1 by TGF-β1 and PPAR-β/δ Modulates Chronic Pressure Overload-Induced Cardiac Fibrosis.
Liu C, Lim ST, Teo MHY, Tan MSY, Kulkarni MD, Qiu B, Li A, Lal S, Dos Remedios CG, Tan NS, Wahli W, Ferenczi MA, Song W, Hong W, Wang X. Liu C, et al. Among authors: Wahli W. Circ Heart Fail. 2019 Dec;12(12):e005962. doi: 10.1161/CIRCHEARTFAILURE.119.005962. Epub 2019 Dec 13. Circ Heart Fail. 2019. PMID: 31830829
Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis.
Kirkby NS, Raouf J, Ahmetaj-Shala B, Liu B, Mazi SI, Edin ML, Chambers MG, Korotkova M, Wang X, Wahli W, Zeldin DC, Nüsing R, Zhou Y, Jakobsson PJ, Mitchell JA. Kirkby NS, et al. Among authors: Wahli W. Cardiovasc Res. 2019 Nov 5:cvz290. doi: 10.1093/cvr/cvz290. Online ahead of print. Cardiovasc Res. 2019. PMID: 31688905
Residual vascular risk in diabetes - Will the SPPARM alpha concept hold the key?
Fruchart JC, Santos RD, Yamashita S, Libby P; International Atherosclerosis Society/R3i Foundation Consensus Panel. Fruchart JC, et al. Diabetes Metab Syndr. 2019 Jul-Aug;13(4):2723-2725. doi: 10.1016/j.dsx.2019.05.034. Epub 2019 May 30. Diabetes Metab Syndr. 2019. PMID: 31405699 Review. No abstract available.
The gut microbiota influences skeletal muscle mass and function in mice.
Lahiri S, Kim H, Garcia-Perez I, Reza MM, Martin KA, Kundu P, Cox LM, Selkrig J, Posma JM, Zhang H, Padmanabhan P, Moret C, Gulyás B, Blaser MJ, Auwerx J, Holmes E, Nicholson J, Wahli W, Pettersson S. Lahiri S, et al. Among authors: Wahli W. Sci Transl Med. 2019 Jul 24;11(502):eaan5662. doi: 10.1126/scitranslmed.aan5662. Sci Transl Med. 2019. PMID: 31341063 Free article.
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