Warfield KL - Search Results

1

UV-4B potently inhibits replication of multiple SARS-CoV-2 strains in clinically relevant human cell lines.

Franco EJ, Warfield KL, Brown AN. Franco EJ, et al. Among authors: warfield kl. Front Biosci (Landmark Ed). 2022 Jan 5;27(1):3. doi: 10.31083/j.fbl2701003. Front Biosci (Landmark Ed). 2022. PMID: 35090308 Free article.

2

Making pain visible: an audit and review of documentation to improve the use of pain assessment by implementing pain as the fifth vital sign.

Purser L, Warfield K, Richardson C. Purser L, et al. Pain Manag Nurs. 2014 Mar;15(1):137-42. doi: 10.1016/j.pmn.2012.07.007. Epub 2012 Sep 8. Pain Manag Nurs. 2014. PMID: 24602432

3

Lack of selective resistance of influenza A virus in presence of host-targeted antiviral, UV-4B.

Warfield KL, Schaaf KR, DeWald LE, Spurgers KB, Wang W, Stavale E, Mendenhall M, Shilts MH, Stockwell TB, Barnard DL, Ramstedt U, Das SR. Warfield KL, et al. Sci Rep. 2019 May 16;9(1):7484. doi: 10.1038/s41598-019-43030-y. Sci Rep. 2019. PMID: 31097731 Free PMC article.

4

Randomized single oral dose phase 1 study of safety, tolerability, and pharmacokinetics of Iminosugar UV-4 Hydrochloride (UV-4B) in healthy subjects.

Callahan M, Treston AM, Lin G, Smith M, Kaufman B, Khaliq M, Evans DeWald L, Spurgers K, Warfield KL, Lowe P, Duchars M, Sampath A, Ramstedt U. Callahan M, et al. Among authors: warfield kl. PLoS Negl Trop Dis. 2022 Aug 8;16(8):e0010636. doi: 10.1371/journal.pntd.0010636. eCollection 2022 Aug. PLoS Negl Trop Dis. 2022. PMID: 35939501 Free PMC article. Clinical Trial.

5

Reproductive and developmental toxicology studies of iminosugar UV-4.

Shearer J, Wolfe G, Khaliq M, Kaufman B, Sampath A, Warfield KL, Ramstedt U, Treston A. Shearer J, et al. Among authors: warfield kl. Reprod Toxicol. 2022 Dec;114:9-21. doi: 10.1016/j.reprotox.2022.09.007. Epub 2022 Oct 4. Reprod Toxicol. 2022. PMID: 36206921 Free article.

6

N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity.

Karade SS, Hill ML, Kiappes JL, Manne R, Aakula B, Zitzmann N, Warfield KL, Treston AM, Mariuzza RA. Karade SS, et al. Among authors: warfield kl. J Med Chem. 2021 Dec 23;64(24):18010-18024. doi: 10.1021/acs.jmedchem.1c01377. Epub 2021 Dec 6. J Med Chem. 2021. PMID: 34870992

7

The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice.

Warfield KL, Barnard DL, Enterlein SG, Smee DF, Khaliq M, Sampath A, Callahan MV, Ramstedt U, Day CW. Warfield KL, et al. Viruses. 2016 Mar 7;8(3):71. doi: 10.3390/v8030071. Viruses. 2016. PMID: 27072420 Free PMC article.

8

Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections.

Warfield KL, Alonzi DS, Hill JC, Caputo AT, Roversi P, Kiappes JL, Sheets N, Duchars M, Dwek RA, Biggins J, Barnard D, Shresta S, Treston AM, Zitzmann N. Warfield KL, et al. J Med Chem. 2020 Apr 23;63(8):4205-4214. doi: 10.1021/acs.jmedchem.0c00067. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32227946

9

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo.

Warfield KL, Warren TK, Qiu X, Wells J, Mire CE, Geisbert JB, Stuthman KS, Garza NL, Van Tongeren SA, Shurtleff AC, Agans KN, Wong G, Callahan MV, Geisbert TW, Klose B, Ramstedt U, Treston AM. Warfield KL, et al. Antiviral Res. 2017 Feb;138:22-31. doi: 10.1016/j.antiviral.2016.11.019. Epub 2016 Nov 28. Antiviral Res. 2017. PMID: 27908828

10

Differential Genome Replication of a Unique Single-Amino-Acid Mutation in the Adenovirus-4 Component of the Live Oral Adenovirus Type 4 and Type 7 Vaccine.

Collins ND, Beaty S, Wallace E, Li Y, Sanborn M, Yang Y, Adhikari A, Shabram P, Warfield K, Karasavvas N, Kuschner RA, Hang J. Collins ND, et al. Vaccines (Basel). 2023 Jun 25;11(7):1144. doi: 10.3390/vaccines11071144. Vaccines (Basel). 2023. PMID: 37514960 Free PMC article.

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