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The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD.
Low ZS, Chua D, Cheng HS, Tee R, Tan WR, Ball C, Sahib NBE, Ng SS, Qu J, Liu Y, Hong H, Cai C, Rao NCL, Wee A, Muthiah MD, Bichler Z, Mickelson B, Kong MS, Tay VS, Yan Z, Chen J, Ng AS, Yip YS, Vos MIG, Tan NA, Lim DL, Lim DXE, Chittezhath M, Yaligar J, Verma SK, Poptani H, Guan XL, Velan SS, Ali Y, Li L, Tan NS, Wahli W. Low ZS, et al. Among authors: wee a. Adv Sci (Weinh). 2024 Sep;11(35):e2404326. doi: 10.1002/advs.202404326. Epub 2024 Jul 1. Adv Sci (Weinh). 2024. PMID: 38952069 Free PMC article.
Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials.
Lackner C, Gouw ASH, Avancini Ferreira Alves V, Arola J, Bedossa P, Behling C, Brunt EM, Burt A, Clouston A, Cummings O, Goodman ZD, Guido M, Guy C, Hubscher SG, Hytiroglou P, Kleiner D, Pai R, Paradis V, Park YN, Rastogi A, Schirmacher P, Wee A, Yano H, Yeh M, Avian A, Tiniakos DG. Lackner C, et al. Among authors: wee a. J Hepatol. 2025 Oct 8:S0168-8278(25)02501-2. doi: 10.1016/j.jhep.2025.09.019. Online ahead of print. J Hepatol. 2025. PMID: 41072805
Targeted inhibition of hepatic de novo ceramide synthesis ameliorates MASH.
Yu X, Huang C, Evers M, Liu J, Ting HJ, Zhang S, Chong SY, Tan MS, Wang S, Sayed N, Gao L, Muthiah MD, Soon GST, Wee A, Chow EK, Soh NJH, Pastorin G, Yu VC, Liu B, Dan YY, Torta F, Schiffelers R, Storm G, Wang JW. Yu X, et al. Among authors: wee a. Sci Adv. 2025 Sep 26;11(39):eadx2681. doi: 10.1126/sciadv.adx2681. Epub 2025 Sep 26. Sci Adv. 2025. PMID: 41004573 Free PMC article.
732 results