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Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19.
Fullard JF, Lee HC, Voloudakis G, Suo S, Javidfar B, Shao Z, Peter C, Zhang W, Jiang S, Corvelo A, Wargnier H, Woodoff-Leith E, Purohit DP, Ahuja S, Tsankova NM, Jette N, Hoffman GE, Akbarian S, Fowkes M, Crary JF, Yuan GC, Roussos P. Fullard JF, et al. Among authors: zhang w. Genome Med. 2021 Jul 19;13(1):118. doi: 10.1186/s13073-021-00933-8. Genome Med. 2021. PMID: 34281603 Free PMC article.
Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression.
Hauberg ME, Zhang W, Giambartolomei C, Franzén O, Morris DL, Vyse TJ, Ruusalepp A; CommonMind Consortium; Sklar P, Schadt EE, Björkegren JLM, Roussos P. Hauberg ME, et al. Among authors: zhang w. Am J Hum Genet. 2017 Jun 1;100(6):885-894. doi: 10.1016/j.ajhg.2017.04.016. Epub 2017 May 25. Am J Hum Genet. 2017. PMID: 28552197 Free PMC article.
Functional annotation of rare structural variation in the human brain.
Han L, Zhao X, Benton ML, Perumal T, Collins RL, Hoffman GE, Johnson JS, Sloofman L, Wang HZ, Stone MR; CommonMind Consortium; Brennand KJ, Brand H, Sieberts SK, Marenco S, Peters MA, Lipska BK, Roussos P, Capra JA, Talkowski M, Ruderfer DM. Han L, et al. Nat Commun. 2020 Jun 12;11(1):2990. doi: 10.1038/s41467-020-16736-1. Nat Commun. 2020. PMID: 32533064 Free PMC article.
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostafavi S; CommonMind Consortium (CMC); The AMP-AD Consortium; Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM. Sieberts SK, et al. Sci Data. 2020 Oct 12;7(1):340. doi: 10.1038/s41597-020-00642-8. Sci Data. 2020. PMID: 33046718 Free PMC article.
IL10RB as a key regulator of COVID-19 host susceptibility and severity.
Voloudakis G, Hoffman G, Venkatesh S, Lee KM, Dobrindt K, Vicari JM, Zhang W, Beckmann ND, Jiang S, Hoagland D, Bian J, Gao L, Corvelo A, Cho K, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Lynch JA, Fullard JF, Roussos P. Voloudakis G, et al. Among authors: zhang w. medRxiv [Preprint]. 2021 Jun 2:2021.05.31.21254851. doi: 10.1101/2021.05.31.21254851. medRxiv. 2021. Update in: NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. PMID: 34100031 Free PMC article. Updated. Preprint.
A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.
Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Fullard JF, Roussos P. Voloudakis G, et al. Among authors: zhang w. NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. NPJ Genom Med. 2022. PMID: 36064543 Free PMC article.
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