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Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice.
Wen Z, Rajagopalan A, Flietner ED, Yun G, Chesi M, Furumo Q, Burns RT, Papadas A, Ranheim EA, Pagenkopf AC, Morrow ZT, Finn R, Zhou Y, Li S, You X, Jensen J, Yu M, Cicala A, Menting J, Mitsiades CS, Callander NS, Bergsagel PL, Wang D, Asimakopoulos F, Zhang J. Wen Z, et al. Among authors: zhou y. Blood. 2021 Jan 7;137(1):61-74. doi: 10.1182/blood.2020007156. Blood. 2021. PMID: 32640012 Free PMC article.
Kras is Required for Adult Hematopoiesis.
Damnernsawad A, Kong G, Wen Z, Liu Y, Rajagopalan A, You X, Wang J, Zhou Y, Ranheim EA, Luo HR, Chang Q, Zhang J. Damnernsawad A, et al. Among authors: zhou y. Stem Cells. 2016 Jul;34(7):1859-71. doi: 10.1002/stem.2355. Epub 2016 Mar 28. Stem Cells. 2016. PMID: 26972179 Free PMC article.
p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia.
Zhang J, Kong G, Rajagopalan A, Lu L, Song J, Hussaini M, Zhang X, Ranheim EA, Liu Y, Wang J, Gao X, Chang YI, Johnson KD, Zhou Y, Yang D, Bhatnagar B, Lucas DM, Bresnick EH, Zhong X, Padron E, Zhang J. Zhang J, et al. Among authors: zhou y. Blood. 2017 Jan 19;129(3):358-370. doi: 10.1182/blood-2016-06-719237. Epub 2016 Nov 4. Blood. 2017. PMID: 27815262 Free PMC article.
Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm.
Kong G, You X, Wen Z, Chang YI, Qian S, Ranheim EA, Letson C, Zhang X, Zhou Y, Liu Y, Rajagopalan A, Zhang J, Stieglitz E, Loh M, Hofmann I, Yang D, Zhong X, Padron E, Zhou L, Pear WS, Zhang J. Kong G, et al. Among authors: zhou y, zhou l. Leukemia. 2019 Mar;33(3):671-685. doi: 10.1038/s41375-018-0248-0. Epub 2018 Sep 11. Leukemia. 2019. PMID: 30206308 Free PMC article.
Unique dependence on Sos1 in Kras G12D -induced leukemogenesis.
You X, Kong G, Ranheim EA, Yang D, Zhou Y, Zhang J. You X, et al. Among authors: zhou y. Blood. 2018 Dec 13;132(24):2575-2579. doi: 10.1182/blood-2018-09-874107. Epub 2018 Oct 30. Blood. 2018. PMID: 30377195 Free PMC article.
Gata2 -77 enhancer regulates adult hematopoietic stem cell survival.
You X, Chang YI, Kong G, Ranheim EA, Zhou Y, Johnson KD, Mehta C, Bresnick EH, Zhang J. You X, et al. Among authors: zhou y. Leukemia. 2021 Mar;35(3):901-905. doi: 10.1038/s41375-020-0942-6. Epub 2020 Jun 27. Leukemia. 2021. PMID: 32594099 Free PMC article. No abstract available.
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