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Page 1
A C. elegans model for neurodegeneration in Cockayne syndrome.
Lopes AFC, Bozek K, Herholz M, Trifunovic A, Rieckher M, Schumacher B. Lopes AFC, et al. Among authors: bozek k. Nucleic Acids Res. 2020 Nov 4;48(19):10973-10985. doi: 10.1093/nar/gkaa795. Nucleic Acids Res. 2020. PMID: 33021672 Free PMC article.
Deep learning-based segmentation and quantification of podocyte foot process morphology suggests differential patterns of foot process effacement across kidney pathologies.
Unnersjö-Jess D, Butt L, Höhne M, Sergei G, Fatehi A, Witasp A, Wernerson A, Patrakka J, Hoyer PF, Blom H, Schermer B, Bozek K, Benzing T. Unnersjö-Jess D, et al. Among authors: bozek k. Kidney Int. 2023 Jun;103(6):1120-1130. doi: 10.1016/j.kint.2023.03.013. Epub 2023 Mar 27. Kidney Int. 2023. PMID: 36990215 Free article.
CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma.
Stahl D, Gödel P, Balke-Want H, Gholamipoorfard R, Segbers P, Tetenborg L, Koker M, Dörr J, Gregor L, Bachurski D, Rose F, Simon AG, Good Z, Jakob J, Häupl B, Nill M, Flümann R, Riet T, Lange D, Blakemore SJ, Baurmann H, Voltin CA, Potter N, Schlözer L, Freihammer M, Wagener-Ryczek S, Iuga AI, Heger JM, Ludwig H, Schleifenbaum JK, Propp J, Bröckelmann PJ, Jachimowicz RD, Knittel G, Borchmann S, Merkelbach-Bruse S, Pallasch C, Peifer M, Rybniker J, Quaas A, Nitz M, Brägelmann J, Müller W, Persigehl T, Bozek K, Theobald SJ, Büttner R, Oellerich T, Hallek M, Kobold S, Chmielewski M, Reinhardt HC, Mackall C, Abedpour N, Borchmann P, Ullrich RT. Stahl D, et al. Among authors: bozek k. Cancer Cell. 2025 Aug 11;43(8):1476-1494.e10. doi: 10.1016/j.ccell.2025.05.013. Epub 2025 Jun 12. Cancer Cell. 2025. PMID: 40513575 Free article.
Histo-Miner: Deep learning based tissue features extraction pipeline from H&E whole slide images of cutaneous squamous cell carcinoma.
Sancéré L, Lorenz C, Helbig D, Persa OD, Dengler S, Kreuter A, Laimer M, Lang R, Fröhlich A, Landsberg J, Brägelmann J, Bozek K. Sancéré L, et al. Among authors: bozek k. PLoS Comput Biol. 2026 Jan 21;22(1):e1013907. doi: 10.1371/journal.pcbi.1013907. eCollection 2026 Jan. PLoS Comput Biol. 2026. PMID: 41564120 Free PMC article.
Deep Learning Histology for Prediction of Lymph Node Metastases and Tumor Regression after Neoadjuvant FLOT Therapy of Gastroesophageal Adenocarcinoma.
Jung JO, Pisula JI, Beyerlein X, Lukomski L, Knipper K, Abu Hejleh AP, Fuchs HF, Tolkach Y, Chon SH, Nienhüser H, Büchler MW, Bruns CJ, Quaas A, Bozek K, Popp F, Schmidt T. Jung JO, et al. Among authors: bozek k. Cancers (Basel). 2024 Jul 3;16(13):2445. doi: 10.3390/cancers16132445. Cancers (Basel). 2024. PMID: 39001507 Free PMC article.
Clinical Validation of Digital PCR-based ctDNA detection for risk stratification in residual triple negative breast cancer: TRICIA trial results.
Roseshter T, Klemantovich A, Lafleur J, Lan C, Cavallone L, Bozek K, Guay J, Elebute O, Jenna S, Ouellette R, McNamara S, Boileau JF, Pelmus M, Brackstone M, Pezo R, Ng T, Aguilar-Mahecha A, Basik M. Roseshter T, et al. Among authors: bozek k. Clin Cancer Res. 2026 Feb 9. doi: 10.1158/1078-0432.CCR-25-2234. Online ahead of print. Clin Cancer Res. 2026. PMID: 41662447
Deep Imputation for Skeleton data (DISK) for behavioral science.
Rose F, Michaluk M, Blindauer T, Ignatowska-Jankowska BM, O'Shaughnessy L, Stephens GJ, Pereira TD, Uusisaari MY, Bozek K. Rose F, et al. Among authors: bozek k. Nat Methods. 2026 Jan;23(1):236-247. doi: 10.1038/s41592-025-02893-y. Epub 2025 Dec 4. Nat Methods. 2026. PMID: 41345771 Free PMC article.
GrandQC: A comprehensive solution to quality control problem in digital pathology.
Weng Z, Seper A, Pryalukhin A, Mairinger F, Wickenhauser C, Bauer M, Glamann L, Bläker H, Lingscheidt T, Hulla W, Jonigk D, Schallenberg S, Bychkov A, Fukuoka J, Braun M, Schömig-Markiefka B, Klein S, Thiel A, Bozek K, Netto GJ, Quaas A, Büttner R, Tolkach Y. Weng Z, et al. Among authors: bozek k. Nat Commun. 2024 Dec 16;15(1):10685. doi: 10.1038/s41467-024-54769-y. Nat Commun. 2024. PMID: 39681557 Free PMC article.
A novel mouse model recapitulating the MMR-defective SCLC subtype uncovers an actionable sensitivity to immune checkpoint blockade.
Ibruli O, Rose F, Beleggia F, Schmitt A, Cartolano M, Fernandez LT, Saggau J, Bonasera D, Kiljan M, Gozum G, Lichius L, Cai J, Niu LN, Caiaffa MI, Herter JM, Walczak H, Liccardi G, Grüll H, Büttner R, Bosco G, George J, Thomas RK, Bozek K, Reinhardt HC, Herter-Sprie GS. Ibruli O, et al. Among authors: bozek k. J Cancer Res Clin Oncol. 2024 Nov 14;150(11):496. doi: 10.1007/s00432-024-05942-9. J Cancer Res Clin Oncol. 2024. PMID: 39542886 Free PMC article.
Enhancing Prostate Cancer Diagnosis: Artificial Intelligence-Driven Virtual Biopsy for Optimal Magnetic Resonance Imaging-Targeted Biopsy Approach and Gleason Grading Strategy.
Harder C, Pryalukhin A, Quaas A, Eich ML, Tretiakova M, Klein S, Seper A, Heidenreich A, Netto GJ, Hulla W, Büttner R, Bozek K, Tolkach Y. Harder C, et al. Among authors: bozek k. Mod Pathol. 2024 Oct;37(10):100564. doi: 10.1016/j.modpat.2024.100564. Epub 2024 Jul 17. Mod Pathol. 2024. PMID: 39029903 Free article.
In vivo characterization of a podocyte-expressed short podocin isoform.
Butt L, Unnersjö-Jess D, Reilly D, Hahnfeldt R, Rinschen MM, Bozek K, Schermer B, Benzing T, Höhne M. Butt L, et al. Among authors: bozek k. BMC Nephrol. 2023 Dec 19;24(1):378. doi: 10.1186/s12882-023-03420-x. BMC Nephrol. 2023. PMID: 38114895 Free PMC article.
LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1.
Vom Stein AF, Rebollido-Rios R, Lukas A, Koch M, von Lom A, Reinartz S, Bachurski D, Rose F, Bozek K, Abdallah AT, Kohlhas V, Saggau J, Zölzer R, Zhao Y, Bruns C, Bröckelmann PJ, Lohneis P, Büttner R, Häupl B, Oellerich T, Nguyen PH, Hallek M. Vom Stein AF, et al. Among authors: bozek k. Nat Commun. 2023 Mar 10;14(1):1330. doi: 10.1038/s41467-023-36824-2. Nat Commun. 2023. PMID: 36899005 Free PMC article.
Predicting the HER2 status in oesophageal cancer from tissue microarrays using convolutional neural networks.
Pisula JI, Datta RR, Valdez LB, Avemarg JR, Jung JO, Plum P, Löser H, Lohneis P, Meuschke M, Dos Santos DP, Gebauer F, Quaas A, Walch A, Bruns CJ, Lawonn K, Popp FC, Bozek K. Pisula JI, et al. Among authors: bozek k. Br J Cancer. 2023 Mar;128(7):1369-1376. doi: 10.1038/s41416-023-02143-y. Epub 2023 Jan 30. Br J Cancer. 2023. PMID: 36717673 Free PMC article.
Interleukin-4 receptor signaling modulates neuronal network activity.
Hanuscheck N, Thalman C, Domingues M, Schmaul S, Muthuraman M, Hetsch F, Ecker M, Endle H, Oshaghi M, Martino G, Kuhlmann T, Bozek K, van Beers T, Bittner S, von Engelhardt J, Vogt J, Vogelaar CF, Zipp F. Hanuscheck N, et al. Among authors: bozek k. J Exp Med. 2022 Jun 6;219(6):e20211887. doi: 10.1084/jem.20211887. Epub 2022 May 19. J Exp Med. 2022. PMID: 35587822 Free PMC article.
Flow-mediated olfactory communication in honeybee swarms.
Nguyen DMT, Iuzzolino ML, Mankel A, Bozek K, Stephens GJ, Peleg O. Nguyen DMT, et al. Among authors: bozek k. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2011916118. doi: 10.1073/pnas.2011916118. Proc Natl Acad Sci U S A. 2021. PMID: 33758099 Free PMC article.
Markerless tracking of an entire honey bee colony.
Bozek K, Hebert L, Portugal Y, Mikheyev AS, Stephens GJ. Bozek K, et al. Nat Commun. 2021 Mar 19;12(1):1733. doi: 10.1038/s41467-021-21769-1. Nat Commun. 2021. PMID: 33741938 Free PMC article.
Publisher Correction: Lipidome determinants of maximal lifespan in mammals.
Bozek K, Khrameeva EE, Reznick J, Omerbašić D, Bennett NC, Lewin GR, Azpurua J, Gorbunova V, Seluanov A, Regnard P, Wanert F, Marchal J, Pifferi F, Aujard F, Liu Z, Shi P, Pääbo S, Schroeder F, Willmitzer L, Giavalisco P, Khaitovich P. Bozek K, et al. Sci Rep. 2019 May 1;9(1):6972. doi: 10.1038/s41598-019-43122-9. Sci Rep. 2019. PMID: 31043659 Free PMC article.
Lipidome Evolution in Mammalian Tissues.
Khrameeva E, Kurochkin I, Bozek K, Giavalisco P, Khaitovich P. Khrameeva E, et al. Among authors: bozek k. Mol Biol Evol. 2018 Aug 1;35(8):1947-1957. doi: 10.1093/molbev/msy097. Mol Biol Evol. 2018. PMID: 29762743 Free PMC article.
Lipidome determinants of maximal lifespan in mammals.
Bozek K, Khrameeva EE, Reznick J, Omerbašić D, Bennett NC, Lewin GR, Azpurua J, Gorbunova V, Seluanov A, Regnard P, Wanert F, Marchal J, Pifferi F, Aujard F, Liu Z, Shi P, Pääbo S, Schroeder F, Willmitzer L, Giavalisco P, Khaitovich P. Bozek K, et al. Sci Rep. 2017 Jan 31;7(1):5. doi: 10.1038/s41598-017-00037-7. Sci Rep. 2017. PMID: 28127055 Free PMC article.
Liquid Crystalline Esters of Dibenzophenazines.
Bozek KJA, Ho KI, Saint-Martin T, Argyropoulos P, Williams VE. Bozek KJA, et al. Materials (Basel). 2015 Jan 14;8(1):270-284. doi: 10.3390/ma8010270. Materials (Basel). 2015. PMID: 28787937 Free PMC article.
Folded discotic dimers.
Bozek KJ, Williams VE. Bozek KJ, et al. Soft Matter. 2014 Aug 21;10(31):5749-54. doi: 10.1039/c4sm01116c. Epub 2014 Jun 30. Soft Matter. 2014. PMID: 24979352
Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness.
Bozek K, Wei Y, Yan Z, Liu X, Xiong J, Sugimoto M, Tomita M, Pääbo S, Pieszek R, Sherwood CC, Hof PR, Ely JJ, Steinhauser D, Willmitzer L, Bangsbo J, Hansson O, Call J, Giavalisco P, Khaitovich P. Bozek K, et al. PLoS Biol. 2014 May 27;12(5):e1001871. doi: 10.1371/journal.pbio.1001871. eCollection 2014 May. PLoS Biol. 2014. PMID: 24866127 Free PMC article.
Circadian transcription in liver.
Bozek K, Rosahl AL, Gaub S, Lorenzen S, Herzel H. Bozek K, et al. Biosystems. 2010 Oct;102(1):61-9. doi: 10.1016/j.biosystems.2010.07.010. Epub 2010 Jul 22. Biosystems. 2010. PMID: 20655353
Regulation of clock-controlled genes in mammals.
Bozek K, Relógio A, Kielbasa SM, Heine M, Dame C, Kramer A, Herzel H. Bozek K, et al. PLoS One. 2009;4(3):e4882. doi: 10.1371/journal.pone.0004882. Epub 2009 Mar 16. PLoS One. 2009. PMID: 19287494 Free PMC article.