Cachofeiro+V - Search Results

1

The mechanisms underlying the cardiac effects of modified citrus pectin in obese rats with myocardial ischemia: Role of galectin-3.

Jiménez-González S, Delgado-Valero B, Romero-Miranda A, Islas F, Luaces M, Ramchandani B, Cuesta-Corral M, Montoro-Garrido A, Nieto ML, Martínez-Martínez E, Cachofeiro V. Jiménez-González S, et al. Clin Investig Arterioscler. 2024 Dec 4:S0214-9168(24)00114-1. doi: 10.1016/j.arteri.2024.10.007. Online ahead of print. Clin Investig Arterioscler. 2024. PMID: 39638645 Free article. English, Spanish.

2

The detrimental role of galectin-3 and endoplasmic reticulum stress in the cardiac consequences of myocardial ischemia in the context of obesity.

Jiménez-González S, Delgado-Valero B, Islas F, Romero-Miranda A, Luaces M, Ramchandani B, Cuesta-Corral M, Montoro-Garrido A, Martínez-Martínez E, Cachofeiro V. Jiménez-González S, et al. FASEB J. 2024 Jul 31;38(14):e23818. doi: 10.1096/fj.202400747R. FASEB J. 2024. PMID: 38989572

3

Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors.

Rodrigues-Diez R, Ballesteros-Martinez C, Moreno-Carriles RM, Nistal F, Díaz Del Campo LS, Cachofeiro V, Dalli J, García-Redondo AB, Redondo JM, Salaices M, Briones AM. Rodrigues-Diez R, et al. Biomed Pharmacother. 2024 May;174:116564. doi: 10.1016/j.biopha.2024.116564. Epub 2024 Apr 11. Biomed Pharmacother. 2024. PMID: 38608525 Free article.

4

Methodology for the induction of myocardial infarction and cardiac function evaluation.

Islas F, Ramchandani B, Cuesta-Corral M, Montoro-Garrido A, Romero-Miranda A, Luaces M, Martínez-Martínez E, Cachofeiro V. Islas F, et al. Methods Cell Biol. 2024;185:151-164. doi: 10.1016/bs.mcb.2024.02.009. Epub 2024 Mar 7. Methods Cell Biol. 2024. PMID: 38556446

5

Importance of cardiac imaging assessment of epicardial adipose tissue after a first episode of myocardial infarction.

Islas F, Gutiérrez E, Cachofeiro V, Martínez-Martínez E, Marín G, Olmos C, Carrión I, Gil S, Mahía P, Cobos MÁ, de Agustín A, Luaces M. Islas F, et al. Front Cardiovasc Med. 2022 Nov 14;9:995367. doi: 10.3389/fcvm.2022.995367. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36451918 Free PMC article.

6

Mitochondrial Oxidative Stress Induces Cardiac Fibrosis in Obese Rats through Modulation of Transthyretin.

Martínez-Martínez E, Fernández-Irigoyen J, Santamaría E, Nieto ML, Bravo-San Pedro JM, Cachofeiro V. Martínez-Martínez E, et al. Int J Mol Sci. 2022 Jul 22;23(15):8080. doi: 10.3390/ijms23158080. Int J Mol Sci. 2022. PMID: 35897655 Free PMC article.

7

Mitochondrial Oxidative Stress Promotes Cardiac Remodeling in Myocardial Infarction through the Activation of Endoplasmic Reticulum Stress.

Souza-Neto FV, Islas F, Jiménez-González S, Luaces M, Ramchandani B, Romero-Miranda A, Delgado-Valero B, Roldan-Molina E, Saiz-Pardo M, Cerón-Nieto MÁ, Ortega-Medina L, Martínez-Martínez E, Cachofeiro V. Souza-Neto FV, et al. Antioxidants (Basel). 2022 Jun 23;11(7):1232. doi: 10.3390/antiox11071232. Antioxidants (Basel). 2022. PMID: 35883722 Free PMC article.

8

Angiotensin II Promotes Skeletal Muscle Angiogenesis Induced by Volume-Dependent Aerobic Exercise Training: Effects on miRNAs-27a/b and Oxidant-Antioxidant Balance.

Rodrigues LF, Pelozin BRA, da Silva Junior ND, Soci UPR, do Carmo EC, da Mota GFA, Cachofeiro V, Lahera V, Oliveira EM, Fernandes T. Rodrigues LF, et al. Antioxidants (Basel). 2022 Mar 28;11(4):651. doi: 10.3390/antiox11040651. Antioxidants (Basel). 2022. PMID: 35453336 Free PMC article.

9

Oxidative Stress in Obesity.

Martínez-Martínez E, Cachofeiro V. Martínez-Martínez E, et al. Antioxidants (Basel). 2022 Mar 26;11(4):639. doi: 10.3390/antiox11040639. Antioxidants (Basel). 2022. PMID: 35453323 Free PMC article.

10

Microsomal prostaglandin E synthase-1 is involved in the metabolic and cardiovascular alterations associated with obesity.

Ballesteros-Martínez C, Rodrigues-Díez R, Beltrán LM, Moreno-Carriles R, Martínez-Martínez E, González-Amor M, Martínez-González J, Rodríguez C, Cachofeiro V, Salaices M, Briones AM. Ballesteros-Martínez C, et al. Br J Pharmacol. 2022 Jun;179(11):2733-2753. doi: 10.1111/bph.15776. Epub 2022 Feb 5. Br J Pharmacol. 2022. PMID: 34877656 Free article.

11

Serum interleukin-6 levels predict kidney disease progression in diabetic nephropathy.

Sanchez-Alamo B, Shabaka A, Cachofeiro V, Cases-Corona C, Fernandez-Juarez G; PRONEDI study investigators. Sanchez-Alamo B, et al. Clin Nephrol. 2022 Jan;97(1):1-9. doi: 10.5414/CN110223. Clin Nephrol. 2022. PMID: 34753557 Clinical Trial.

12

The Interplay of Mitochondrial Oxidative Stress and Endoplasmic Reticulum Stress in Cardiovascular Fibrosis in Obese Rats.

Souza-Neto FV, Jiménez-González S, Delgado-Valero B, Jurado-López R, Genty M, Romero-Miranda A, Rodríguez C, Nieto ML, Martínez-Martínez E, Cachofeiro V. Souza-Neto FV, et al. Antioxidants (Basel). 2021 Aug 11;10(8):1274. doi: 10.3390/antiox10081274. Antioxidants (Basel). 2021. PMID: 34439522 Free PMC article.

13

Fibrosis, the Bad Actor in Cardiorenal Syndromes: Mechanisms Involved.

Delgado-Valero B, Cachofeiro V, Martínez-Martínez E. Delgado-Valero B, et al. Cells. 2021 Jul 19;10(7):1824. doi: 10.3390/cells10071824. Cells. 2021. PMID: 34359993 Free PMC article. Review.

14

Oxidative Stress and Vascular Damage in the Context of Obesity: The Hidden Guest.

Martínez-Martínez E, Souza-Neto FV, Jiménez-González S, Cachofeiro V. Martínez-Martínez E, et al. Antioxidants (Basel). 2021 Mar 8;10(3):406. doi: 10.3390/antiox10030406. Antioxidants (Basel). 2021. PMID: 33800427 Free PMC article. Review.

15

Role of endoplasmic reticulum stress in renal damage after myocardial infarction.

Delgado-Valero B, de la Fuente-Chávez L, Romero-Miranda A, Visitación Bartolomé M, Ramchandani B, Islas F, Luaces M, Cachofeiro V, Martínez-Martínez E. Delgado-Valero B, et al. Clin Sci (Lond). 2021 Jan 15;135(1):143-159. doi: 10.1042/CS20201137. Clin Sci (Lond). 2021. PMID: 33355632

16

Oleanolic acid ameliorates intestinal alterations associated with EAE.

Gutierrez B, Gallardo I, Ruiz L, Alvarez Y, Cachofeiro V, Margolles A, Hernandez M, Nieto ML. Gutierrez B, et al. J Neuroinflammation. 2020 Nov 27;17(1):363. doi: 10.1186/s12974-020-02042-6. J Neuroinflammation. 2020. PMID: 33246492 Free PMC article.

17

Identification of a Plasma Microrna Signature as Biomarker of Subaneurysmal Aortic Dilation in Patients with High Cardiovascular Risk.

Torres-Do Rego A, Barrientos M, Ortega-Hernández A, Modrego J, Gómez-Gordo R, Álvarez-Sala LA, Cachofeiro V, Gómez-Garre D. Torres-Do Rego A, et al. J Clin Med. 2020 Aug 28;9(9):2783. doi: 10.3390/jcm9092783. J Clin Med. 2020. PMID: 32872191 Free PMC article.

18

The Interaction between Mitochondrial Oxidative Stress and Gut Microbiota in the Cardiometabolic Consequences in Diet-Induced Obese Rats.

Ortega-Hernández A, Martínez-Martínez E, Gómez-Gordo R, López-Andrés N, Fernández-Celis A, Gutiérrrez-Miranda B, Nieto ML, Alarcón T, Alba C, Gómez-Garre D, Cachofeiro V. Ortega-Hernández A, et al. Antioxidants (Basel). 2020 Jul 21;9(7):640. doi: 10.3390/antiox9070640. Antioxidants (Basel). 2020. PMID: 32708095 Free PMC article.

19

A Role for MMP-10 (Matrix Metalloproteinase-10) in Calcific Aortic Valve Stenosis.

Matilla L, Roncal C, Ibarrola J, Arrieta V, García-Peña A, Fernández-Celis A, Navarro A, Álvarez V, Gainza A, Orbe J, Cachofeiro V, Zalba G, Sádaba R, Rodríguez JA, López-Andrés N. Matilla L, et al. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1370-1382. doi: 10.1161/ATVBAHA.120.314143. Epub 2020 Mar 19. Arterioscler Thromb Vasc Biol. 2020. PMID: 32188274 Free article.

20

The Crosstalk between Cardiac Lipotoxicity and Mitochondrial Oxidative Stress in the Cardiac Alterations in Diet-Induced Obesity in Rats.

Jiménez-González S, Marín-Royo G, Jurado-López R, Bartolomé MV, Romero-Miranda A, Luaces M, Islas F, Nieto ML, Martínez-Martínez E, Cachofeiro V. Jiménez-González S, et al. Cells. 2020 Feb 17;9(2):451. doi: 10.3390/cells9020451. Cells. 2020. PMID: 32079154 Free PMC article.

21

Secreted Phospholipase A₂-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation-Fibrosis Link.

Martin R, Gutierrez B, Cordova C, Roman AS, Alvarez Y, Hernandez M, Cachofeiro V, Nieto ML. Martin R, et al. Cells. 2020 Feb 8;9(2):396. doi: 10.3390/cells9020396. Cells. 2020. PMID: 32046347 Free PMC article.

22

Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges.

Martínez-González J, Varona S, Cañes L, Galán M, Briones AM, Cachofeiro V, Rodríguez C. Martínez-González J, et al. Biomolecules. 2019 Oct 14;9(10):610. doi: 10.3390/biom9100610. Biomolecules. 2019. PMID: 31615160 Free PMC article. Review.

23

The role of mitochondrial oxidative stress in the metabolic alterations in diet-induced obesity in rats.

Marín-Royo G, Rodríguez C, Le Pape A, Jurado-López R, Luaces M, Antequera A, Martínez-González J, Souza-Neto FV, Nieto ML, Martínez-Martínez E, Cachofeiro V. Marín-Royo G, et al. FASEB J. 2019 Nov;33(11):12060-12072. doi: 10.1096/fj.201900347RR. Epub 2019 Aug 1. FASEB J. 2019. PMID: 31370681 Free PMC article.

24

The Impact of Cardiac Lipotoxicity on Cardiac Function and Mirnas Signature in Obese and Non-Obese Rats with Myocardial Infarction.

Marín-Royo G, Ortega-Hernández A, Martínez-Martínez E, Jurado-López R, Luaces M, Islas F, Gómez-Garre D, Delgado-Valero B, Lagunas E, Ramchandani B, García-Bouza M, Nieto ML, Cachofeiro V. Marín-Royo G, et al. Sci Rep. 2019 Jan 24;9(1):444. doi: 10.1038/s41598-018-36914-y. Sci Rep. 2019. PMID: 30679580 Free PMC article.

25

mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress.

Avendaño MS, García-Redondo AB, Zalba G, González-Amor M, Aguado A, Martínez-Revelles S, Beltrán LM, Camacho M, Cachofeiro V, Alonso MJ, Salaices M, Briones AM. Avendaño MS, et al. Hypertension. 2018 Aug;72(2):492-502. doi: 10.1161/HYPERTENSIONAHA.118.10833. Epub 2018 Jun 11. Hypertension. 2018. PMID: 29891646 Free article.

26

Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12.

Ibarrola J, Sadaba R, Martinez-Martinez E, Garcia-Peña A, Arrieta V, Alvarez V, Fernández-Celis A, Gainza A, Cachofeiro V, Santamaria E, Fernandez-Irigoyen J, Jaisser F, Lopez-Andres N. Ibarrola J, et al. Sci Rep. 2018 May 1;8(1):6801. doi: 10.1038/s41598-018-25068-6. Sci Rep. 2018. PMID: 29717226 Free PMC article.

27

Galectin-3 down-regulates antioxidant peroxiredoxin-4 in human cardiac fibroblasts: a new pathway to induce cardiac damage.

Ibarrola J, Arrieta V, Sádaba R, Martinez-Martinez E, Garcia-Peña A, Alvarez V, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Cachofeiro V, Zalba G, Fay R, Rossignol P, López-Andrés N. Ibarrola J, et al. Clin Sci (Lond). 2018 Jul 18;132(13):1471-1485. doi: 10.1042/CS20171389. Print 2018 Jul 18. Clin Sci (Lond). 2018. PMID: 29674526

28

A role for fumarate hydratase in mediating oxidative effects of galectin-3 in human cardiac fibroblasts.

Ibarrola J, Sádaba R, Garcia-Peña A, Arrieta V, Martinez-Martinez E, Alvarez V, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Cachofeiro V, Fay R, Rossignol P, López-Andrés N. Ibarrola J, et al. Int J Cardiol. 2018 May 1;258:217-223. doi: 10.1016/j.ijcard.2017.12.103. Int J Cardiol. 2018. PMID: 29544935

29

Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity.

Marín-Royo G, Gallardo I, Martínez-Martínez E, Gutiérrez B, Jurado-López R, López-Andrés N, Gutiérrez-Tenorio J, Rial E, Bartolomé MAV, Nieto ML, Cachofeiro V. Marín-Royo G, et al. Dis Model Mech. 2018 Feb 5;11(2):dmm032086. doi: 10.1242/dmm.032086. Dis Model Mech. 2018. PMID: 29361517 Free PMC article.

30

The role of oxidative stress in the crosstalk between leptin and mineralocorticoid receptor in the cardiac fibrosis associated with obesity.

Gutiérrez-Tenorio J, Marín-Royo G, Martínez-Martínez E, Martín R, Miana M, López-Andrés N, Jurado-López R, Gallardo I, Luaces M, San Román JA, González-Amor M, Salaices M, Nieto ML, Cachofeiro V. Gutiérrez-Tenorio J, et al. Sci Rep. 2017 Dec 1;7(1):16802. doi: 10.1038/s41598-017-17103-9. Sci Rep. 2017. PMID: 29196758 Free PMC article.

31

The impact of obesity in the cardiac lipidome and its consequences in the cardiac damage observed in obese rats.

Marín-Royo G, Martínez-Martínez E, Gutiérrez B, Jurado-López R, Gallardo I, Montero O, Bartolomé MV, San Román JA, Salaices M, Nieto ML, Cachofeiro V. Marín-Royo G, et al. Clin Investig Arterioscler. 2018 Jan-Feb;30(1):10-20. doi: 10.1016/j.arteri.2017.07.004. Epub 2017 Aug 30. Clin Investig Arterioscler. 2018. PMID: 28869040 Free article. English, Spanish.

32

Galectin-3 pharmacological inhibition attenuates early renal damage in spontaneously hypertensive rats.

Martínez-Martínez E, Ibarrola J, Fernández-Celis A, Calvier L, Leroy C, Cachofeiro V, Rossignol P, López-Andrés N. Martínez-Martínez E, et al. J Hypertens. 2018 Feb;36(2):368-376. doi: 10.1097/HJH.0000000000001545. J Hypertens. 2018. PMID: 28858976

33

A role for galectin-3 in the development of early molecular alterations in short-term aortic stenosis.

Arrieta V, Martinez-Martinez E, Ibarrola J, Alvarez V, Sádaba R, Garcia-Peña A, Fernández-Celis A, Cachofeiro V, Rossignol P, López-Andrés N. Arrieta V, et al. Clin Sci (Lond). 2017 May 1;131(10):935-949. doi: 10.1042/CS20170145. Epub 2017 Mar 30. Clin Sci (Lond). 2017. PMID: 28360193

34

Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels.

Lucas E, Vila-Bedmar R, Arcones AC, Cruces-Sande M, Cachofeiro V, Mayor F Jr, Murga C. Lucas E, et al. Cardiovasc Diabetol. 2016 Nov 10;15(1):155. doi: 10.1186/s12933-016-0474-6. Cardiovasc Diabetol. 2016. PMID: 27832814 Free PMC article.

35

Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage.

Martinez-Martinez E, Ibarrola J, Calvier L, Fernandez-Celis A, Leroy C, Cachofeiro V, Rossignol P, Lopez-Andres N. Martinez-Martinez E, et al. PLoS One. 2016 Nov 9;11(11):e0166272. doi: 10.1371/journal.pone.0166272. eCollection 2016. PLoS One. 2016. PMID: 27829066 Free PMC article.

36

Role for Galectin-3 in Calcific Aortic Valve Stenosis.

Sádaba JR, Martínez-Martínez E, Arrieta V, Álvarez V, Fernández-Celis A, Ibarrola J, Melero A, Rossignol P, Cachofeiro V, López-Andrés N. Sádaba JR, et al. J Am Heart Assoc. 2016 Nov 4;5(11):e004360. doi: 10.1161/JAHA.116.004360. J Am Heart Assoc. 2016. PMID: 27815266 Free PMC article.

37

High levels of circulating TNFR1 increase the risk of all-cause mortality and progression of renal disease in type 2 diabetic nephropathy.

Fernández-Juárez G, Villacorta Perez J, Luño Fernández JL, Martinez-Martinez E, Cachofeiro V, Barrio Lucia V, Tato Ribera AM, Mendez Abreu A, Cordon A, Oliva Dominguez JA, Praga Terente M. Fernández-Juárez G, et al. Nephrology (Carlton). 2017 May;22(5):354-360. doi: 10.1111/nep.12781. Nephrology (Carlton). 2017. PMID: 27003829 Clinical Trial.

38

Galectin-3 inhibition prevents adipose tissue remodelling in obesity.

Martínez-Martínez E, Calvier L, Rossignol P, Rousseau E, Fernández-Celis A, Jurado-López R, Laville M, Cachofeiro V, López-Andrés N. Martínez-Martínez E, et al. Int J Obes (Lond). 2016 Jun;40(6):1034-8. doi: 10.1038/ijo.2016.19. Epub 2016 Feb 8. Int J Obes (Lond). 2016. PMID: 26853916

39

The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.

Martínez-Martínez E, Rodríguez C, Galán M, Miana M, Jurado-López R, Bartolomé MV, Luaces M, Islas F, Martínez-González J, López-Andrés N, Cachofeiro V. Martínez-Martínez E, et al. J Mol Cell Cardiol. 2016 Mar;92:96-104. doi: 10.1016/j.yjmcc.2016.01.012. Epub 2016 Jan 15. J Mol Cell Cardiol. 2016. PMID: 26780438

40

Galectin-3 Participates in Cardiovascular Remodeling Associated With Obesity.

Martínez-Martínez E, López-Ándres N, Jurado-López R, Rousseau E, Bartolomé MV, Fernández-Celis A, Rossignol P, Islas F, Antequera A, Prieto S, Luaces M, Cachofeiro V. Martínez-Martínez E, et al. Hypertension. 2015 Nov;66(5):961-9. doi: 10.1161/HYPERTENSIONAHA.115.06032. Epub 2015 Sep 8. Hypertension. 2015. PMID: 26351031

41

Red wine intake but not other alcoholic beverages increases total antioxidant capacity and improves pro-inflammatory profile after an oral fat diet in healthy volunteers.

Torres A, Cachofeiro V, Millán J, Lahera V, Nieto ML, Martín R, Bello E, Alvarez-Sala LA. Torres A, et al. Rev Clin Esp (Barc). 2015 Dec;215(9):486-94. doi: 10.1016/j.rce.2015.07.002. Epub 2015 Aug 18. Rev Clin Esp (Barc). 2015. PMID: 26297333 English, Spanish.

42

Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertension.

Martínez-Martínez E, Calvier L, Fernández-Celis A, Rousseau E, Jurado-López R, Rossoni LV, Jaisser F, Zannad F, Rossignol P, Cachofeiro V, López-Andrés N. Martínez-Martínez E, et al. Hypertension. 2015 Oct;66(4):767-75. doi: 10.1161/HYPERTENSIONAHA.115.05876. Epub 2015 Aug 3. Hypertension. 2015. PMID: 26238446

43

The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats.

Miana M, Galán M, Martínez-Martínez E, Varona S, Jurado-López R, Bausa-Miranda B, Antequera A, Luaces M, Martínez-González J, Rodríguez C, Cachofeiro V. Miana M, et al. Dis Model Mech. 2015 Jun;8(6):543-51. doi: 10.1242/dmm.020107. Epub 2015 Apr 7. Dis Model Mech. 2015. PMID: 26035864 Free PMC article.

44

Interleukin-33/ST2 system attenuates aldosterone-induced adipogenesis and inflammation.

Martínez-Martínez E, Cachofeiro V, Rousseau E, Álvarez V, Calvier L, Fernández-Celis A, Leroy C, Miana M, Jurado-López R, Briones AM, Jaisser F, Zannad F, Rossignol P, López-Andrés N. Martínez-Martínez E, et al. Mol Cell Endocrinol. 2015 Aug 15;411:20-7. doi: 10.1016/j.mce.2015.04.007. Epub 2015 Apr 17. Mol Cell Endocrinol. 2015. PMID: 25896545

45

Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension.

Hernanz R, Martínez-Revelles S, Palacios R, Martín A, Cachofeiro V, Aguado A, García-Redondo L, Barrús MT, de Batista PR, Briones AM, Salaices M, Alonso MJ. Hernanz R, et al. Br J Pharmacol. 2015 Jun;172(12):3159-76. doi: 10.1111/bph.13117. Epub 2015 Apr 10. Br J Pharmacol. 2015. PMID: 25712370 Free PMC article.

46

The impact of galectin-3 inhibition on aldosterone-induced cardiac and renal injuries.

Calvier L, Martinez-Martinez E, Miana M, Cachofeiro V, Rousseau E, Sádaba JR, Zannad F, Rossignol P, López-Andrés N. Calvier L, et al. JACC Heart Fail. 2015 Jan;3(1):59-67. doi: 10.1016/j.jchf.2014.08.002. Epub 2014 Nov 11. JACC Heart Fail. 2015. PMID: 25458174 Free article.

47

The endocrine and cardiovascular systems: a close liaison.

Cachofeiro V, Lahera V. Cachofeiro V, et al. Horm Mol Biol Clin Investig. 2014 Apr;18(1):1-2. doi: 10.1515/hmbci-2014-0018. Horm Mol Biol Clin Investig. 2014. PMID: 25390001 No abstract available.

48

Leptin, a mediator of cardiac damage associated with obesity.

Martínez-Martínez E, Jurado-López R, Cervantes-Escalera P, Cachofeiro V, Miana M. Martínez-Martínez E, et al. Horm Mol Biol Clin Investig. 2014 Apr;18(1):3-14. doi: 10.1515/hmbci-2013-0060. Horm Mol Biol Clin Investig. 2014. PMID: 25389996 Free article. Review.

49

Antagonistic effect of TNF-alpha and insulin on uncoupling protein 2 (UCP-2) expression and vascular damage.

Gómez-Hernández A, Perdomo L, de las Heras N, Beneit N, Escribano O, Otero YF, Guillén C, Díaz-Castroverde S, Gozalbo-López B, Cachofeiro V, Lahera V, Benito M. Gómez-Hernández A, et al. Cardiovasc Diabetol. 2014 Jul 31;13:108. doi: 10.1186/s12933-014-0108-9. Cardiovasc Diabetol. 2014. PMID: 25077985 Free PMC article.

50

Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the human disease.

Martín R, Cordova C, San Román JA, Gutierrez B, Cachofeiro V, Nieto ML. Martín R, et al. J Mol Cell Cardiol. 2014 Jul;72:250-62. doi: 10.1016/j.yjmcc.2014.04.002. Epub 2014 Apr 13. J Mol Cell Cardiol. 2014. PMID: 24732212

51

Leptin induces cardiac fibrosis through galectin-3, mTOR and oxidative stress: potential role in obesity.

Martínez-Martínez E, Jurado-López R, Valero-Muñoz M, Bartolomé MV, Ballesteros S, Luaces M, Briones AM, López-Andrés N, Miana M, Cachofeiro V. Martínez-Martínez E, et al. J Hypertens. 2014 May;32(5):1104-14; discussion 1114. doi: 10.1097/HJH.0000000000000149. J Hypertens. 2014. PMID: 24695395

52

[Rosuvastatin improves insulin sensitivity in overweight rats induced by high fat diet. Role of SIRT1 in adipose tissue].

Valero-Muñoz M, Martín-Fernández B, Ballesteros S, Cachofeiro V, Lahera V, de Las Heras N. Valero-Muñoz M, et al. Clin Investig Arterioscler. 2014 Jul-Aug;26(4):161-7. doi: 10.1016/j.arteri.2013.12.005. Epub 2014 Mar 4. Clin Investig Arterioscler. 2014. PMID: 24612843 Spanish.

53

The potential role of leptin in the vascular remodeling associated with obesity.

Martínez-Martínez E, Miana M, Jurado-López R, Bartolomé MV, Souza Neto FV, Salaices M, López-Andrés N, Cachofeiro V. Martínez-Martínez E, et al. Int J Obes (Lond). 2014 Dec;38(12):1565-72. doi: 10.1038/ijo.2014.37. Epub 2014 Mar 3. Int J Obes (Lond). 2014. PMID: 24583853

54

A role for soluble ST2 in vascular remodeling associated with obesity in rats.

Martínez-Martínez E, Miana M, Jurado-López R, Rousseau E, Rossignol P, Zannad F, Cachofeiro V, López-Andrés N. Martínez-Martínez E, et al. PLoS One. 2013 Nov 12;8(11):e79176. doi: 10.1371/journal.pone.0079176. eCollection 2013. PLoS One. 2013. PMID: 24265755 Free PMC article.

55

25 (OH) vitamin D levels and renal disease progression in patients with type 2 diabetic nephropathy and blockade of the renin-angiotensin system.

Fernández-Juárez G, Luño J, Barrio V, de Vinuesa SG, Praga M, Goicoechea M, Lahera V, Casas L, Oliva J; PRONEDI Study Group. Fernández-Juárez G, et al. Clin J Am Soc Nephrol. 2013 Nov;8(11):1870-6. doi: 10.2215/CJN.00910113. Epub 2013 Oct 17. Clin J Am Soc Nephrol. 2013. PMID: 24135218 Free PMC article. Clinical Trial.

56

Left and right ventricle late remodeling following myocardial infarction in rats.

Stefanon I, Valero-Muñoz M, Fernandes AA, Ribeiro RF Jr, Rodríguez C, Miana M, Martínez-González J, Spalenza JS, Lahera V, Vassallo PF, Cachofeiro V. Stefanon I, et al. PLoS One. 2013 May 31;8(5):e64986. doi: 10.1371/journal.pone.0064986. Print 2013. PLoS One. 2013. PMID: 23741440 Free PMC article.

57

Factors involved in rosuvastatin induction of insulin sensitization in rats fed a high fat diet.

de las Heras N, Valero-Muñoz M, Ballesteros S, Gómez-Hernández A, Martín-Fernández B, Blanco-Rivero J, Cachofeiro V, Benito M, Balfagón G, Lahera V. de las Heras N, et al. Nutr Metab Cardiovasc Dis. 2013 Nov;23(11):1107-14. doi: 10.1016/j.numecd.2012.11.009. Epub 2013 Feb 20. Nutr Metab Cardiovasc Dis. 2013. PMID: 23434394

58

Mercury induces proliferation and reduces cell size in vascular smooth muscle cells through MAPK, oxidative stress and cyclooxygenase-2 pathways.

Aguado A, Galán M, Zhenyukh O, Wiggers GA, Roque FR, Redondo S, Peçanha F, Martín A, Fortuño A, Cachofeiro V, Tejerina T, Salaices M, Briones AM. Aguado A, et al. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):188-200. doi: 10.1016/j.taap.2013.01.030. Epub 2013 Feb 13. Toxicol Appl Pharmacol. 2013. PMID: 23415682

59

Relevance of vascular peroxisome proliferator-activated receptor γ coactivator-1α to molecular alterations in atherosclerosis.

Valero-Muñoz M, Martín-Fernández B, Ballesteros S, Martínez-Martínez E, Blanco-Rivero J, Balfagón G, Cachofeiro V, Lahera V, de las Heras N. Valero-Muñoz M, et al. Exp Physiol. 2013 May;98(5):999-1008. doi: 10.1113/expphysiol.2012.070557. Epub 2013 Jan 18. Exp Physiol. 2013. PMID: 23335007 Free article.

60

The impact of bariatric surgery on renal and cardiac functions in morbidly obese patients.

Luaces M, Martínez-Martínez E, Medina M, Miana M, González N, Fernández-Pérez C, Cachofeiro V. Luaces M, et al. Nephrol Dial Transplant. 2012 Dec;27 Suppl 4:iv53-7. doi: 10.1093/ndt/gfs529. Nephrol Dial Transplant. 2012. PMID: 23258812

61

Galectin-3 mediates aldosterone-induced vascular fibrosis.

Calvier L, Miana M, Reboul P, Cachofeiro V, Martinez-Martinez E, de Boer RA, Poirier F, Lacolley P, Zannad F, Rossignol P, López-Andrés N. Calvier L, et al. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):67-75. doi: 10.1161/ATVBAHA.112.300569. Epub 2012 Nov 1. Arterioscler Thromb Vasc Biol. 2013. PMID: 23117656

62

Aerobic exercise reduces oxidative stress and improves vascular changes of small mesenteric and coronary arteries in hypertension.

Roque FR, Briones AM, García-Redondo AB, Galán M, Martínez-Revelles S, Avendaño MS, Cachofeiro V, Fernandes T, Vassallo DV, Oliveira EM, Salaices M. Roque FR, et al. Br J Pharmacol. 2013 Feb;168(3):686-703. doi: 10.1111/j.1476-5381.2012.02224.x. Br J Pharmacol. 2013. PMID: 22994554 Free PMC article.

63

Ezetimibe inhibits PMA-induced monocyte/macrophage differentiation by altering microRNA expression: a novel anti-atherosclerotic mechanism.

Muñoz-Pacheco P, Ortega-Hernández A, Miana M, Cachofeiro V, Fernández-Cruz A, Gómez-Garre D. Muñoz-Pacheco P, et al. Pharmacol Res. 2012 Dec;66(6):536-43. doi: 10.1016/j.phrs.2012.09.005. Epub 2012 Sep 15. Pharmacol Res. 2012. PMID: 22989505

64

Effect of dual blockade of the renin-angiotensin system on the progression of type 2 diabetic nephropathy: a randomized trial.

Fernandez Juarez G, Luño J, Barrio V, de Vinuesa SG, Praga M, Goicoechea M, Cachofeiro V, Nieto J, Fernández Vega F, Tato A, Gutierrez E; PRONEDI Study Group. Fernandez Juarez G, et al. Am J Kidney Dis. 2013 Feb;61(2):211-8. doi: 10.1053/j.ajkd.2012.07.011. Epub 2012 Aug 29. Am J Kidney Dis. 2013. PMID: 22939518 Clinical Trial.

65

DIOL triterpenes block profibrotic effects of angiotensin II and protect from cardiac hypertrophy.

Martín R, Miana M, Jurado-López R, Martínez-Martínez E, Gómez-Hurtado N, Delgado C, Bartolomé MV, San Román JA, Cordova C, Lahera V, Nieto ML, Cachofeiro V. Martín R, et al. PLoS One. 2012;7(7):e41545. doi: 10.1371/journal.pone.0041545. Epub 2012 Jul 23. PLoS One. 2012. PMID: 22844495 Free PMC article.

66

Cardiotrophin-1 induces sarcoplasmic reticulum Ca(2+) leak and arrhythmogenesis in adult rat ventricular myocytes.

Ruiz-Hurtado G, Gómez-Hurtado N, Fernández-Velasco M, Calderón E, Smani T, Ordoñez A, Cachofeiro V, Boscá L, Díez J, Gómez AM, Delgado C. Ruiz-Hurtado G, et al. Cardiovasc Res. 2012 Oct 1;96(1):81-9. doi: 10.1093/cvr/cvs234. Epub 2012 Jul 11. Cardiovasc Res. 2012. PMID: 22787135

67

A wound-like inflammatory aortic response in chronic portal hypertensive rats.

de Las Heras N, Aller MA, Martín-Fernández B, Miana M, Ballesteros S, Regadera J, Cachofeiro V, Arias J, Lahera V. de Las Heras N, et al. Mol Immunol. 2012 Jun;51(2):177-87. doi: 10.1016/j.molimm.2012.03.016. Epub 2012 Mar 29. Mol Immunol. 2012. PMID: 22463791

68

Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1.

Martín-Fernández B, de las Heras N, Miana M, Ballesteros S, Valero-Muñoz M, Vassallo D, Davel AP, Rossoni LV, Cachofeiro V, Lahera V. Martín-Fernández B, et al. Exp Physiol. 2012 Jun;97(6):710-8. doi: 10.1113/expphysiol.2011.063230. Epub 2012 Feb 10. Exp Physiol. 2012. PMID: 22327331 Free article.

69

Brown fat lipoatrophy and increased visceral adiposity through a concerted adipocytokines overexpression induces vascular insulin resistance and dysfunction.

Gómez-Hernández A, Otero YF, de las Heras N, Escribano O, Cachofeiro V, Lahera V, Benito M. Gómez-Hernández A, et al. Endocrinology. 2012 Mar;153(3):1242-55. doi: 10.1210/en.2011-1765. Epub 2012 Jan 17. Endocrinology. 2012. PMID: 22253415

70

The effects of adiponectin and leptin on human endothelial cell proliferation: a live-cell study.

Alvarez G, Visitación Bartolomé M, Miana M, Jurado-López R, Martín R, Zuluaga P, Martinez-Martinez E, Nieto ML, Alvarez-Sala LA, Millán J, Lahera V, Cachofeiro V. Alvarez G, et al. J Vasc Res. 2012;49(2):111-22. doi: 10.1159/000332332. Epub 2012 Jan 13. J Vasc Res. 2012. PMID: 22249107

71

Cardiac benefits of exercise training in aging spontaneously hypertensive rats.

Rossoni LV, Oliveira RA, Caffaro RR, Miana M, Sanz-Rosa D, Koike MK, Do Amaral SL, Michelini LC, Lahera V, Cachofeiro V. Rossoni LV, et al. J Hypertens. 2011 Dec;29(12):2349-58. doi: 10.1097/HJH.0b013e32834d2532. J Hypertens. 2011. PMID: 22045123

72

Anatomical and functional alterations of the heart in morbid obesity. Changes after bariatric surgery.

Luaces M, Cachofeiro V, García-Muñoz-Najar A, Medina M, González N, Cancer E, Rodríguez-Robles A, Cánovas G, Antequera-Pérez A. Luaces M, et al. Rev Esp Cardiol (Engl Ed). 2012 Jan;65(1):14-21. doi: 10.1016/j.recesp.2011.06.018. Epub 2011 Oct 19. Rev Esp Cardiol (Engl Ed). 2012. PMID: 22015018 English, Spanish.

73

Interplay of hypertension, inflammation, and angiotensin II.

Lahera V, Cachofeiro V, de Las Heras N. Lahera V, et al. Am J Hypertens. 2011 Oct;24(10):1059. doi: 10.1038/ajh.2011.142. Am J Hypertens. 2011. PMID: 21927010 No abstract available.

74

A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone.

López-Andrés N, Martin-Fernandez B, Rossignol P, Zannad F, Lahera V, Fortuno MA, Cachofeiro V, Díez J. López-Andrés N, et al. Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2372-82. doi: 10.1152/ajpheart.00283.2011. Epub 2011 Sep 16. Am J Physiol Heart Circ Physiol. 2011. PMID: 21926338 Free article.

75

Exposure to low mercury concentration in vivo impairs myocardial contractile function.

Furieri LB, Fioresi M, Junior RF, Bartolomé MV, Fernandes AA, Cachofeiro V, Lahera V, Salaices M, Stefanon I, Vassallo DV. Furieri LB, et al. Toxicol Appl Pharmacol. 2011 Sep 1;255(2):193-9. doi: 10.1016/j.taap.2011.06.015. Epub 2011 Jun 24. Toxicol Appl Pharmacol. 2011. PMID: 21723307 Free article.

76

Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells.

Guadall A, Orriols M, Alcudia JF, Cachofeiro V, Martinez-Gonzalez J, Rodriguez C. Guadall A, et al. Front Biosci (Elite Ed). 2011 Jun 1;3(3):955-67. doi: 10.2741/e301. Front Biosci (Elite Ed). 2011. PMID: 21622104 Free article.

77

Effect of eplerenone on hypertension-associated renal damage in rats: potential role of peroxisome proliferator activated receptor gamma (PPAR-γ).

Miana M, de Las Heras N, Rodriguez C, Sanz-Rosa D, Martin-Fernandez B, Mezzano S, Lahera V, Martinez-Gonzalez J, Cachofeiro V. Miana M, et al. J Physiol Pharmacol. 2011 Feb;62(1):87-94. J Physiol Pharmacol. 2011. PMID: 21451213 Free article.

78

Endothelial dysfunction of rat coronary arteries after exposure to low concentrations of mercury is dependent on reactive oxygen species.

Furieri LB, Galán M, Avendaño MS, García-Redondo AB, Aguado A, Martínez S, Cachofeiro V, Bartolomé MV, Alonso MJ, Vassallo DV, Salaices M. Furieri LB, et al. Br J Pharmacol. 2011 Apr;162(8):1819-31. doi: 10.1111/j.1476-5381.2011.01203.x. Br J Pharmacol. 2011. PMID: 21232032 Free PMC article.

79

Aldosterone and the cardiovascular system: a dangerous association.

Cachofeiro V, López-Andrés N, Miana M, Martín-Fernández B, de Las Heras N, Martínez E, Lahera V, Fortuño MA. Cachofeiro V, et al. Horm Mol Biol Clin Investig. 2010 Dec 1;4(2):539-48. doi: 10.1515/HMBCI.2010.057. Horm Mol Biol Clin Investig. 2010. PMID: 25961230

80

Structural, functional, and molecular alterations produced by aldosterone plus salt in rat heart: association with enhanced serum and glucocorticoid-regulated kinase-1 expression.

Martín-Fernández B, de las Heras N, Miana M, Ballesteros S, Delgado C, Song S, Hintze T, Cachofeiro V, Lahera V. Martín-Fernández B, et al. J Cardiovasc Pharmacol. 2011 Jan;57(1):114-21. doi: 10.1097/FJC.0b013e31820088ca. J Cardiovasc Pharmacol. 2011. PMID: 20980916

81

Rosuvastatin restored adrenergic and nitrergic function in mesenteric arteries from obese rats.

Blanco-Rivero J, de las Heras N, Martín-Fernández B, Cachofeiro V, Lahera V, Balfagón G. Blanco-Rivero J, et al. Br J Pharmacol. 2011 Jan;162(1):271-85. doi: 10.1111/j.1476-5381.2010.01030.x. Br J Pharmacol. 2011. PMID: 20840472 Free PMC article.

82

Mechanisms underlying the activation of L-type calcium channels by urocortin in rat ventricular myocytes.

Smani T, Calderón-Sanchez E, Gómez-Hurtado N, Fernández-Velasco M, Cachofeiro V, Lahera V, Ordoñez A, Delgado C. Smani T, et al. Cardiovasc Res. 2010 Aug 1;87(3):459-66. doi: 10.1093/cvr/cvq063. Epub 2010 Feb 26. Cardiovasc Res. 2010. PMID: 20189952 Free article.

83

A proteomic approach to determine changes in proteins involved in the myocardial metabolism in left ventricles of spontaneously hypertensive rats.

Zamorano-León JJ, Modrego J, Mateos-Cáceres PJ, Macaya C, Martín-Fernández B, Miana M, de las Heras N, Cachofeiro V, Lahera V, López-Farré AJ. Zamorano-León JJ, et al. Cell Physiol Biochem. 2010;25(2-3):347-58. doi: 10.1159/000276567. Epub 2010 Jan 12. Cell Physiol Biochem. 2010. PMID: 20110695

84

The protective effect of irbesartan in rats fed a high fat diet is associated with modification of leptin-adiponectin imbalance.

de las Heras N, Martín-Fernández B, Miana M, Ballesteros S, Oubiña MP, López-Farré AJ, Cachofeiro V, Lahera V. de las Heras N, et al. J Hypertens Suppl. 2009 Aug;27(6):S37-41. doi: 10.1097/01.hjh.0000358836.64052.43. J Hypertens Suppl. 2009. PMID: 19633450

85

Inflammation but not endothelial dysfunction is associated with the severity of coronary artery disease in dyslipidemic subjects.

Rueda-Clausen CF, López-Jaramillo P, Luengas C, del Pilar Oubiña M, Cachofeiro V, Lahera V. Rueda-Clausen CF, et al. Mediators Inflamm. 2009;2009:469169. doi: 10.1155/2009/469169. Epub 2009 Jun 23. Mediators Inflamm. 2009. PMID: 19584917 Free PMC article.

86

Response to 'Treatment with statins may be considered in ESRD patients for primary prevention of cardiovascular disease'.

Cachofeiro V, Lahera V, Goicochea M, de Vinuesa SG, Luño J. Cachofeiro V, et al. Kidney Int. 2009 Jun;75(12):1355. doi: 10.1038/ki.2009.111. Kidney Int. 2009. PMID: 19483752 No abstract available.

87

Urocortin induces positive inotropic effect in rat heart.

Calderón-Sanchez E, Delgado C, Ruiz-Hurtado G, Domínguez-Rodríguez A, Cachofeiro V, Rodríguez-Moyano M, Gomez AM, Ordóñez A, Smani T. Calderón-Sanchez E, et al. Cardiovasc Res. 2009 Sep 1;83(4):717-25. doi: 10.1093/cvr/cvp161. Epub 2009 May 21. Cardiovasc Res. 2009. PMID: 19460778 Free article.

88

Cardiac L-type calcium current is increased in a model of hyperaldosteronism in the rat.

Martin-Fernandez B, Miana M, De Las Heras N, Ruiz-Hurtado G, Fernandez-Velasco M, Bas M, Ballesteros S, Lahera V, Cachofeiro V, Delgado C. Martin-Fernandez B, et al. Exp Physiol. 2009 Jun;94(6):675-83. doi: 10.1113/expphysiol.2009.047688. Epub 2009 Apr 24. Exp Physiol. 2009. PMID: 19395659 Free article.

89

Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease.

Cachofeiro V, Goicochea M, de Vinuesa SG, Oubiña P, Lahera V, Luño J. Cachofeiro V, et al. Kidney Int Suppl. 2008 Dec;(111):S4-9. doi: 10.1038/ki.2008.516. Kidney Int Suppl. 2008. PMID: 19034325 Free article. Review.

90

Fenofibrate and pioglitazone do not ameliorate the altered vascular reactivity in aorta of isoproterenol-treated rats.

Fukuda LE, Davel AP, Verissimo-Filho S, Lopes LR, Cachofeiro V, Lahera V, Rossoni LV. Fukuda LE, et al. J Cardiovasc Pharmacol. 2008 Nov;52(5):413-21. doi: 10.1097/FJC.0b013e31818a8927. J Cardiovasc Pharmacol. 2008. PMID: 19033820

91

The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors.

Rueda-Clausen CF, Lahera V, Calderón J, Bolivar IC, Castillo VR, Gutiérrez M, Carreño M, Oubiña Mdel P, Cachofeiro V, López-Jaramillo P. Rueda-Clausen CF, et al. Int J Cardiol. 2010 Feb 18;139(1):32-41. doi: 10.1016/j.ijcard.2008.09.005. Epub 2008 Oct 14. Int J Cardiol. 2010. PMID: 18922591

92

Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries.

Wiggers GA, Peçanha FM, Briones AM, Pérez-Girón JV, Miguel M, Vassallo DV, Cachofeiro V, Alonso MJ, Salaices M. Wiggers GA, et al. Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H1033-H1043. doi: 10.1152/ajpheart.00430.2008. Epub 2008 Jul 3. Am J Physiol Heart Circ Physiol. 2008. PMID: 18599595 Free article.

93

Specific amelioration of cerebral endothelial dysfunction in hypertensive patients treated with atorvastatin.

Lahera V, Cachofeiro V. Lahera V, et al. Am J Hypertens. 2008 Jun;21(6):604. doi: 10.1038/ajh.2008.163. Am J Hypertens. 2008. PMID: 18500327 No abstract available.

94

Effects of isoproterenol treatment for 7 days on inflammatory mediators in the rat aorta.

Davel AP, Fukuda LE, De Sá LL, Munhoz CD, Scavone C, Sanz-Rosa D, Cachofeiro V, Lahera V, Rossoni LV. Davel AP, et al. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H211-9. doi: 10.1152/ajpheart.00581.2007. Epub 2008 May 16. Am J Physiol Heart Circ Physiol. 2008. PMID: 18487443 Free article.

95

Aldosterone and the vascular system.

Cachofeiro V, Miana M, de Las Heras N, Martín-Fernández B, Ballesteros S, Fernández-Tresguerres J, Lahera V. Cachofeiro V, et al. J Steroid Biochem Mol Biol. 2008 Apr;109(3-5):331-5. doi: 10.1016/j.jsbmb.2008.03.005. Epub 2008 Mar 6. J Steroid Biochem Mol Biol. 2008. PMID: 18400490 Review.

96

Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-label, parallel-group study.

Alvarez-Sala LA, Cachofeiro V, Masana L, Suarez C, Pinilla B, Plana N, Trias F, Moreno MA, Gambus G, Lahera V, Pintó X. Alvarez-Sala LA, et al. Clin Ther. 2008 Jan;30(1):84-97. doi: 10.1016/j.linthera.2008.01.013. Clin Ther. 2008. PMID: 18343245 Clinical Trial.

97

Role of connective tissue growth factor in vascular and renal damage associated with hypertension in rats. Interactions with angiotensin II.

de las Heras N, Ruiz-Ortega M, Rupérez M, Sanz-Rosa D, Miana M, Aragoncillo P, Mezzano S, Lahera V, Egido J, Cachofeiro V. de las Heras N, et al. J Renin Angiotensin Aldosterone Syst. 2006 Dec;7(4):192-200. doi: 10.3317/jraas.2006.037. J Renin Angiotensin Aldosterone Syst. 2006. PMID: 17318787 Free article.

98

Interactions between aldosterone and connective tissue growth factor in vascular and renal damage in spontaneously hypertensive rats.

de las Heras N, Ruiz-Ortega M, Miana M, Rupérez M, Sanz-Rosa D, Aragoncillo P, Mezzano S, Cachofeiro V, Egido J, Lahera V. de las Heras N, et al. J Hypertens. 2007 Mar;25(3):629-38. doi: 10.1097/HJH.0b013e3280112ce5. J Hypertens. 2007. PMID: 17278980

99

Endothelial dysfunction, oxidative stress and inflammation in atherosclerosis: beneficial effects of statins.

Lahera V, Goicoechea M, de Vinuesa SG, Miana M, de las Heras N, Cachofeiro V, Luño J. Lahera V, et al. Curr Med Chem. 2007;14(2):243-8. doi: 10.2174/092986707779313381. Curr Med Chem. 2007. PMID: 17266583 Review.

100

Effects of atorvastatin on inflammatory and fibrinolytic parameters in patients with chronic kidney disease.

Goicoechea M, de Vinuesa SG, Lahera V, Cachofeiro V, Gómez-Campderá F, Vega A, Abad S, Luño J. Goicoechea M, et al. J Am Soc Nephrol. 2006 Dec;17(12 Suppl 3):S231-5. doi: 10.1681/ASN.2006080938. J Am Soc Nephrol. 2006. PMID: 17130267 Clinical Trial.

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